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Morphological attributes from histopathological images and molecular profiles from genomic data are important information to drive diagnosis, prognosis, and therapy of cancers. By integrating these heterogeneous but complementary data, many…

Machine Learning · Computer Science 2022-02-28 Kaiwen Tan , Weixian Huang , Xiaofeng Liu , Jinlong Hu , Shoubin Dong

A recent popular approach to out-of-distribution (OOD) detection is based on a self-supervised learning technique referred to as contrastive learning. There are two main variants of contrastive learning, namely instance and class…

Machine Learning · Computer Science 2022-11-08 Nawid Keshtmand , Raul Santos-Rodriguez , Jonathan Lawry

Multimodal learning aims to imitate human beings to acquire complementary information from multiple modalities for various downstream tasks. However, traditional aggregation-based multimodal fusion methods ignore the inter-modality…

Computer Vision and Pattern Recognition · Computer Science 2023-05-17 Heqing Zou , Meng Shen , Chen Chen , Yuchen Hu , Deepu Rajan , Eng Siong Chng

Multi-task learning has recently emerged as a promising solution for a comprehensive understanding of complex scenes. In addition to being memory-efficient, multi-task models, when appropriately designed, can facilitate the exchange of…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Ivan Lopes , Tuan-Hung Vu , Raoul de Charette

Whole Slide Images (WSIs) are critical for various clinical applications, including histopathological analysis. However, current deep learning approaches in this field predominantly focus on individual tumor types, limiting model…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Sharon Peled , Yosef E. Maruvka , Moti Freiman

Low-dose CT (LDCT) images are often accompanied by significant noise, which negatively impacts image quality and subsequent diagnostic accuracy. To address the challenges of multi-scale feature fusion and diverse noise distribution patterns…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Zhiting Zheng , Shuqi Wu , Wen Ding

Several prior studies have suggested that word frequency biases can cause the Bert model to learn indistinguishable sentence embeddings. Contrastive learning schemes such as SimCSE and ConSERT have already been adopted successfully in…

Computation and Language · Computer Science 2023-09-15 Pu Miao , Zeyao Du , Junlin Zhang

Contrastive learning has proven instrumental in learning unbiased representations of data, especially in complex environments characterized by high-cardinality and high-dimensional sensitive information. However, existing approaches within…

Machine Learning · Computer Science 2024-11-25 Stefan K. Nielsen , Tan M. Nguyen

Multimodal learning, integrating histology images and genomics, promises to enhance precision oncology with comprehensive views at microscopic and molecular levels. However, existing methods may not sufficiently model the shared or…

Computer Vision and Pattern Recognition · Computer Science 2024-06-12 Huahui Yi , Xiaofei Wang , Kang Li , Chao Li

Missing data is a recurrent and challenging problem, especially when using machine learning algorithms for real-world applications. For this reason, missing data imputation has become an active research area, in which recent deep learning…

Machine Learning · Computer Science 2021-07-01 Simon Tihon , Muhammad Usama Javaid , Damien Fourure , Nicolas Posocco , Thomas Peel

Language-supervised vision models have recently attracted great attention in computer vision. A common approach to build such models is to use contrastive learning on paired data across the two modalities, as exemplified by Contrastive…

Machine Learning · Computer Science 2023-03-16 Ryumei Nakada , Halil Ibrahim Gulluk , Zhun Deng , Wenlong Ji , James Zou , Linjun Zhang

Esophageal cancer is among the most common types of cancer worldwide. It is traditionally treated using open esophagectomy, but in recent years, robot-assisted minimally invasive esophagectomy (RAMIE) has emerged as a promising alternative.…

For anomaly detection (AD), early approaches often train separate models for individual classes, yielding high performance but posing challenges in scalability and resource management. Recent efforts have shifted toward training a single…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Lei Fan , Junjie Huang , Donglin Di , Anyang Su , Tianyou Song , Maurice Pagnucco , Yang Song

Multiview clustering (MVC) segregates data samples into meaningful clusters by synthesizing information across multiple views. Moreover, deep learning-based methods have demonstrated their strong feature learning capabilities in MVC…

Machine Learning · Computer Science 2024-03-22 Hao Yang , Hua Mao , Wai Lok Woo , Jie Chen , Xi Peng

The computational burden and inherent redundancy of large-scale datasets challenge the training of contemporary machine learning models. Data pruning offers a solution by selecting smaller, informative subsets, yet existing methods…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Feiyang Kang , Nadine Chang , Maying Shen , Marc T. Law , Rafid Mahmood , Ruoxi Jia , Jose M. Alvarez

High-throughput screening technology has facilitated the generation of large-scale drug responses across hundreds of cancer cell lines. However, there exists significant discrepancy between in vitro cell lines and actual tumors in vivo in…

Machine Learning · Computer Science 2023-11-17 Jia Zhai , Hui Liu

Early detection through imaging and accurate diagnosis is crucial in mitigating the high mortality rate associated with breast cancer. However, locating tumors from low-resolution and high-noise medical images is extremely challenging.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Feiyan Feng , Tianyu Liu , Hong Wang , Jun Zhao , Wei Li , Yanshen Sun

Learning representations that transfer well to diverse downstream tasks remains a central challenge in representation learning. Existing paradigms -- contrastive learning, self-supervised masking, and denoising auto-encoders -- balance this…

Machine Learning · Computer Science 2025-09-29 Micha Livne

Dimension reduction is an essential tool for analyzing high dimensional data. Most existing methods, including principal component analysis (PCA), as well as their extensions, provide principal components that are often linear combinations…

Methodology · Statistics 2025-08-18 Eric Zhang , Michael Love , Didong Li

Contrastive Learning (CL), a leading paradigm in Self-Supervised Learning (SSL), typically relies on pairs of data views generated through augmentation. While multiple augmentations per instance (more than two) improve generalization in…

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