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Universal Machine Learning Interatomic Potentials (uMLIPs), pre-trained on massively diverse datasets encompassing inorganic materials and organic molecules across the entire periodic table, serve as foundational models for quantum-accurate…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-20 Yuanchang Zhou , Hongyu Wang , Yiming Du , Yan Wang , Mingzhen Li , Siyu Hu , Xiangyu Zhang , Weijian Liu , Chen Wang , Zhuoqiang Guo , Long Wang , Jingde Bu , Yutong Lu , Guangming Tan , Weile Jia

Machine learning interatomic potentials (MLIPs) have transformed materials discovery by leveraging graph neural networks (GNNs) to predict material properties with near density functional theory (DFT) accuracy. While large-scale pretrained…

Materials Science · Physics 2026-05-29 Rushikesh Pawar , Harshit Rawat , Ayush Kumar , Phani Motamarri

Pretrained universal machine-learning interatomic potentials (MLIPs) have revolutionized computational materials science by enabling rapid atomistic simulations as efficient alternatives to ab initio methods. Fine-tuning pretrained MLIPs…

Materials Science · Physics 2025-06-19 Jisu Kim , Jiho Lee , Sangmin Oh , Yutack Park , Seungwoo Hwang , Seungwu Han , Sungwoo Kang , Youngho Kang

Interatomic potential models based on machine learning (ML) are rapidly developing as tools for materials simulations. However, because of their flexibility, they require large fitting databases that are normally created with substantial…

Materials Science · Physics 2019-11-19 Noam Bernstein , Gábor Csányi , Volker L. Deringer

Model-Agnostic Meta-Learning (MAML) and its variants are popular few-shot classification methods. They train an initializer across a variety of sampled learning tasks (also known as episodes) such that the initialized model can adapt…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Yangbin Chen , Yun Ma , Tom Ko , Jianping Wang , Qing Li

Discovering atom-level phenomena requires molecular dynamics (MD) simulations with ab initio accuracy. Machine learning interatomic potentials (MLIPs) enable stable, high-accuracy MD simulations, and their models exhibit scaling-law trends…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-20 Hongyu Wang , Weijian Liu , Hongtao Xu , Yan Wang , Mingzhen Li , Weile Jia , Guangming Tan

Machine-learning potentials (MLPs) for atomistic simulations are a promising alternative to conventional classical potentials. Current approaches rely on descriptors of the local atomic environment with dimensions that increase…

Materials Science · Physics 2017-12-05 Nongnuch Artrith , Alexander Urban , Gerbrand Ceder

Computational quantum chemistry plays a critical role in drug discovery, chemical synthesis, and materials science. While first-principles methods, such as density functional theory (DFT), provide high accuracy in modeling electronic…

Despite the rapid and significant advancements in deep learning for Quantitative Structure-Activity Relationship (QSAR) models, the challenge of learning robust molecular representations that effectively generalize in real-world scenarios…

Machine Learning · Computer Science 2024-05-28 Jose Arjona-Medina , Ramil Nugmanov

Machine learning potentials have emerged as a means to enhance the accuracy of biomolecular simulations. However, their application is constrained by the significant computational cost arising from the vast number of parameters compared to…

Combining the efficiency of semi-empirical potentials with the accuracy of quantum mechanical methods, machine-learning interatomic potentials (MLIPs) have significantly advanced atomistic modeling in computational materials science and…

Materials Science · Physics 2025-05-20 Jiantao Wang , Peitao Liu , Heyu Zhu , Mingfeng Liu , Hui Ma , Yun Chen , Yan Sun , Xing-Qiu Chen

Machine learning interatomic potentials (MLIPs) require generating computationally expensive, large-scale training datasets to accurately simulate materials and molecules. Incorporating electronic structure information using multitask…

Chemical Physics · Physics 2026-05-26 Ihor Neporozhnii , Sjoerd Hoogland , Oleksandr Voznyy

Machine-learning interatomic potentials (MLIPs) such as neuroevolution potentials (NEP) combine quantum-mechanical accuracy with computational efficiency significantly accelerate atomistic dynamic simulations. Trained by derivative-free…

Disordered Systems and Neural Networks · Physics 2026-04-14 Hongfu Huang , Junhao Peng , Kaiqi Li , Jian Zhou , Zhimei Sun

Automated analyses of the outcome of a simulation have been an important part of atomistic modeling since the early days, addressing the need of linking the behavior of individual atoms and the collective properties that are usually the…

Chemical Physics · Physics 2019-05-22 Michele Ceriotti

A central capability of intelligent systems is the ability to continuously build upon previous experiences to speed up and enhance learning of new tasks. Two distinct research paradigms have studied this question. Meta-learning views this…

Machine Learning · Computer Science 2019-07-05 Chelsea Finn , Aravind Rajeswaran , Sham Kakade , Sergey Levine

We assess the accuracy of six universal machine-learned interatomic potentials (MLIPs) for predicting the temperature and pressure response of materials by molecular dynamics simulations. Accuracy is evaluated across 13 diverse materials…

Materials Science · Physics 2025-12-01 Konstantin Stracke , Connor W. Edwards , Jack D. Evans

Recent years have witnessed an abundance of new publications and approaches on meta-learning. This community-wide enthusiasm has sparked great insights but has also created a plethora of seemingly different frameworks, which can be hard to…

Machine Learning · Computer Science 2020-02-04 Wei-Lun Chao , Han-Jia Ye , De-Chuan Zhan , Mark Campbell , Kilian Q. Weinberger

Machine learning (ML) has become widely used in the development of interatomic potentials for molecular dynamics simulations. However, most ML potentials are still much slower than classical interatomic potentials and are usually trained…

Materials Science · Physics 2024-08-29 Aslak Fellman , Jesper Byggmästar , Fredric Granberg , Kai Nordlund , Flyura Djurabekova

Typically, loss functions, regularization mechanisms and other important aspects of training parametric models are chosen heuristically from a limited set of options. In this paper, we take the first step towards automating this process,…

The development of resilient and lightweight Aluminum alloys is central to advancing structural materials for energy-efficient engineering applications. To address this challenge, in this study, we explore the elastic properties of Al-Mg-Zr…