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Tractography is a unique method for mapping white matter connections in the brain, but tractography algorithms suffer from an inherent trade-off between sensitivity and specificity that limits accuracy. Incorporating prior knowledge of…

Computational Engineering, Finance, and Science · Computer Science 2025-11-10 Elinor Thompson , Tiantian He , Anna Schroder , Ahmed Abdulaal , Alec Sargood , Sonja Soskic , Henry F. J. Tregidgo , Daniel C. Alexander

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

Localization of anatomical landmarks is essential for clinical diagnosis, treatment planning, and research. In this paper, we propose a novel deep network, named feature aggregation and refinement network (FARNet), for the automatic…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Yueyuan Ao , Hong Wu

Traumatic brain injury (TBI) disrupts thalamocortical connectivity, contributing to cognitive impairment and post-traumatic epilepsy (PTE). This study presents a novel tractography-based framework that leverages diffusion maps to capture…

Quantitative Methods · Quantitative Biology 2025-10-21 Akul Sharma , Anand A. Joshi , Richard M. Leahy

The brain white matter consists of a set of tracts that connect distinct regions of the brain. Segmentation of these tracts is often needed for clinical and research studies. Diffusion-weighted MRI offers unique contrast to delineate these…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Hamza Kebiri , Ali Gholipour , Meritxell Bach Cuadra , Davood Karimi

Accurately identifying white matter tracts in medical images is essential for various applications, including surgery planning and tract-specific analysis. Supervised machine learning models have reached state-of-the-art solving this task…

Image and Video Processing · Electrical Eng. & Systems 2023-08-04 Robin Peretzke , Klaus Maier-Hein , Jonas Bohn , Yannick Kirchhoff , Saikat Roy , Sabrina Oberli-Palma , Daniela Becker , Pavlina Lenga , Peter Neher

White matter fiber clustering is an important strategy for white matter parcellation, which enables quantitative analysis of brain connections in health and disease. In combination with expert neuroanatomical labeling, data-driven white…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Yuqian Chen , Chaoyi Zhang , Tengfei Xue , Yang Song , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

Diffusion MRI tractography enables in vivo reconstruction of white matter (WM) pathways. Two key tasks in tractography analysis include: 1) tractogram registration that aligns streamlines across individuals, and 2) streamline clustering…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Yijie Li , Xi Zhu , Junyi Wang , Ye Wu , Lauren J. O'Donnell , Fan Zhang

One of the main issues of the current tractography methods is their high false-positive rate. Tractogram filtering is an option to remove false-positive streamlines from tractography data in a post-processing step. In this paper, we train a…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Daniel Jörgens , Pierre-Marc Jodoin , Maxime Descoteaux , Rodrigo Moreno

We present a novel deep learning framework that uses dynamic functional connectivity to simultaneously localize the language and motor areas of the eloquent cortex in brain tumor patients. Our method leverages convolutional layers to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-18 Naresh Nandakumar , Niharika Shimona D'souza , Komal Manzoor , Jay J. Pillai , Sachin K. Gujar , Haris I. Sair , Archana Venkataraman

Trajectory prediction aims to estimate an entity's future path using its current position and historical movement data, benefiting fields like autonomous navigation, robotics, and human movement analytics. Deep learning approaches have…

Machine Learning · Computer Science 2025-04-08 Amirhossein Nadiri , Jing Li , Ali Faraji , Ghadeer Abuoda , Manos Papagelis

We propose a new method, Patch-CNN, for diffusion tensor (DT) estimation from only six-direction diffusion weighted images (DWI). Deep learning-based methods have been recently proposed for dMRI parameter estimation, using either voxel-wise…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Tobias Goodwin-Allcock , Ting Gong , Robert Gray , Parashkev Nachev , Hui Zhang

Tractography algorithms are used extensively to delineate white matter structures, by operating on the voxel-wise information generated through the application of diffusion tensor imaging (DTI) or other models to diffusion weighted (DW)…

Quantitative Methods · Quantitative Biology 2024-03-05 Richard G. Carson , Alexander Leemans

Target identification for tractography studies requires solid anatomical knowledge validated by an extensive literature review across species for each seed structure to be studied. Manual literature review to identify targets for a given…

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections at macro scale. Over the last two decades, the study of brain connectivity using…

Quantitative Methods · Quantitative Biology 2021-04-26 Fan Zhang , Alessandro Daducci , Yong He , Simona Schiavi , Caio Seguin , Robert Smith , Chun-Hung Yeh , Tengda Zhao , Lauren J. O'Donnell

Diffusion MRI tractography parcellation classifies streamlines into anatomical fiber tracts to enable quantification and visualization for clinical and scientific applications. Current tractography parcellation methods rely heavily on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-19 Tengfei Xue , Yuqian Chen , Chaoyi Zhang , Alexandra J. Golby , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

Understanding Greenland's subglacial topography is critical for projecting the future mass loss of the ice sheet and its contribution to global sea-level rise. However, the complex and sparse nature of observational data, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Bayu Adhi Tama , Mansa Krishna , Homayra Alam , Mostafa Cham , Omar Faruque , Gong Cheng , Jianwu Wang , Mathieu Morlighem , Vandana Janeja

The retinogeniculate pathway (RGVP) is responsible for carrying visual information from the retina to the lateral geniculate nucleus. Identification and visualization of the RGVP are important in studying the anatomy of the visual system…

Understanding dynamic 3D environment is crucial for robotic agents and many other applications. We propose a novel neural network architecture called $MeteorNet$ for learning representations for dynamic 3D point cloud sequences. Different…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Xingyu Liu , Mengyuan Yan , Jeannette Bohg

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial strategy for white matter (WM) parcellation. Current methods primarily use the geometric information of fibers (i.e., the spatial trajectories) to group similar fibers…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Jin Wang , Bocheng Guo , Yijie Li , Junyi Wang , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang