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This paper applies a hidden Markov model to the problem of Attention Deficit Hyperactivity Disorder (ADHD) diagnosis from resting-state functional Magnetic Resonance Image (fMRI) scans of subjects. The proposed model considers the temporal…

Quantitative Methods · Quantitative Biology 2015-06-22 Bhaskar Sen , Zheng Shi , Gregory Burlet

Epileptic biomarkers play a crucial role in identifying the origin of seizures, an essential aspect of pre-surgical planning for epilepsy treatment. These biomarkers can vary significantly over time. By studying these temporal fluctuations,…

Signal Processing · Electrical Eng. & Systems 2025-11-11 Mehdi Zekriyapanah Gashti , Mostafa Mohammadpour , Hassan Eshkiki , Vahid Ghanbarizadeh

Human cognitive performance is critical to productivity, learning, and accident avoidance. Cognitive performance varies throughout each day and is in part driven by intrinsic, near 24-hour circadian rhythms. Prior research on the impact of…

Human-Computer Interaction · Computer Science 2017-02-28 Tim Althoff , Eric Horvitz , Ryen W. White , Jamie Zeitzer

Detecting monotonic changes in heart rate (HR) is crucial for early identification of cardiac conditions and health management. This is particularly important for dementia patients, where HR trends can signal stress or agitation. Developing…

It has recently been observed that the occurrence of sudden cardiac death has a close statistical relationship with the time of day, viz., ventricular fibrillation is most likely to occur between 12 am-6 am, with 6 pm-12 am being the next…

Tissues and Organs · Quantitative Biology 2016-09-30 Pavithraa Seenivasan , Shakti N. Menon , S. Sridhar , Sitabhra Sinha

Resting-state functional MRI (rs-fMRI) is a rich imaging modality that captures spontaneous brain activity patterns, revealing clues about the connectomic organization of the human brain. While many rs-fMRI studies have focused on static…

Machine Learning · Computer Science 2019-08-20 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert R. Sabuncu

Use of accelerometers is now widespread within animal biotelemetry as they provide a means of measuring an animal's activity in a meaningful and quantitative way where direct observation is not possible. In sequential acceleration data…

Circadian clocks play a pivotal role in orchestrating numerous physiological and developmental events. Waveform shapes of the oscillations of protein abundances can be informative about the underlying biochemical processes of circadian…

Subcellular Processes · Quantitative Biology 2018-11-27 Hang-Hyun Jo , Yeon Jeong Kim , Jae Kyoung Kim , Mathias Foo , David E. Somers , Pan-Jun Kim

We present a Bayesian approach to estimate the parameters of mathematical models of cardiac electrophysiology with quantified uncertainty. Such models capture the dynamics of the electrical signal that coordinates the muscle cell…

Numerical Analysis · Mathematics 2026-04-02 Maarten Volkaerts , Marie Cloet , Hans Dierckx , Piet Claus , Giovanni Samaey

Hidden Markov models (HMMs) and their extensions have proven to be powerful tools for classification of observations that stem from systems with temporal dependence as they take into account that observations close in time are likely…

Applications · Statistics 2021-11-22 Sofia Ruiz-Suarez , Vianey Leos-Barajas , Juan Manuel Morales

We introduce a class of causal hidden quantum Markov models (cHQMMs) that reverse the usual order of hidden updates and emissions compared to conventional HQMMs. Using a simple qubit model with a rotating hidden state and sharp…

Mathematical Physics · Physics 2026-04-08 Abdessatar Souissi , Abdessatar Barhoumi

Large-scale electrophysiological recordings now allow simultaneous monitoring of thousands of neurons across multiple brain regions, revealing structured variability in neural population activity. Understanding how these collective patterns…

Neurons and Cognition · Quantitative Biology 2026-03-12 Nicolas Béreux , Giovanni Catania , Aurélien Decelle , Francesca Mignacco , Alfonso de Jesús Navas Gómez , Beatriz Seoane

Human Activity Recognition (HAR) is a crucial technology for many applications such as smart homes, surveillance, human assistance and health care. This technology utilises pattern recognition and can contribute to the development of…

Human-Computer Interaction · Computer Science 2022-06-10 Farhad Nazari , Darius Nahavandi , Navid Mohajer , Abbas Khosravi

The growth in Remote Patient Monitoring (RPM) services using wearable and non-wearable Internet of Medical Things (IoMT) promises to improve the quality of diagnosis and facilitate timely treatment for a gamut of medical conditions. At the…

Machine Learning · Computer Science 2021-06-23 Deepti Gupta , Maanak Gupta , Smriti Bhatt , Ali Saman Tosun

Daylight plays a major role in the wake/sleep cycle in humans. Indeed, the wake/sleep system stems from biological systems that follow a circadian rhythm determined by the light/dark alternation. The oscillations can be modeled by the…

Biological Physics · Physics 2022-01-13 F. L. Tsafack Tayong , R. Yamapi , G. Filatrella

Heart rate variability (HRV) is a practical and noninvasive measure of autonomic nervous system activity, which plays an essential role in cardiovascular health. However, using HRV to assess physiology status is challenging. Even in…

Signal Processing · Electrical Eng. & Systems 2022-03-24 Jiacheng Zhu , Gregory Darnell , Agni Kumar , Ding Zhao , Bo Li , Xuanlong Nguyen , Shirley You Ren

Behavior trees are rapidly attracting interest in robotics and human task-related motion tracking. However no algorithms currently exist to track or identify parameters of BTs under noisy observations. We report a new relationship between…

Robotics · Computer Science 2019-07-24 Blake Hannaford

Functional brain networks exhibit dynamics on the sub-second temporal scale and are often assumed to embody the physiological substrate of cognitive processes. Here we analyse the temporal and spatial dynamics of these states, as measured…

Neurons and Cognition · Quantitative Biology 2016-06-09 Tammo Rukat , Adam Baker , Andrew Quinn , Mark Woolrich

Cardiovascular-Kidney-Metabolic (CKM) syndrome represents a growing public health crisis, yet the subclinical heterogeneity of its component systems remains underexplored. Early detection of physiological deviation is critical for…

Cardiovascular diseases are best diagnosed using multiple modalities that assess both the heart's electrical and mechanical functions. While effective, imaging techniques like echocardiography and nuclear imaging are costly and not widely…

Medical Physics · Physics 2024-10-28 Sajjad Karimi , Shirin Karimi , Amit J. Shah , Gari D. Clifford , Reza Sameni
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