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Accurately measuring the evolution of Multiple Sclerosis (MS) with magnetic resonance imaging (MRI) critically informs understanding of disease progression and helps to direct therapeutic strategy. Deep learning models have shown promise…

Segmentation of white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we explore segmentation solutions based on convolutional…

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Deploying deep learning (DL) models in medical applications relies on predictive performance and other critical factors, such as conveying trustworthy predictive uncertainty. Uncertainty estimation (UE) methods provide potential solutions…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Kudaibergen Abutalip , Numan Saeed , Ikboljon Sobirov , Vincent Andrearczyk , Adrien Depeursinge , Mohammad Yaqub

We consider a model-agnostic solution to the problem of Multi-Domain Learning (MDL) for multi-modal applications. Many existing MDL techniques are model-dependent solutions which explicitly require nontrivial architectural changes to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-01 Anthony Sicilia , Xingchen Zhao , Davneet Minhas , Erin O'Connor , Howard Aizenstein , William Klunk , Dana Tudorascu , Seong Jae Hwang

Diffusion-Weighted Magnetic Resonance Imaging (DWI) is widely used for early cerebral infarct detection caused by ischemic stroke. Manual segmentation is done by a radiologist as a common clinical process, nonetheless, challenges of…

Computer Vision and Pattern Recognition · Computer Science 2018-03-29 Noranart Vesdapunt , Nongluk Covavisaruch

Super-resolution is widely used in medical imaging to enhance low-quality data, reducing scan time and improving abnormality detection. Conventional super-resolution approaches typically rely on paired datasets of downsampled and original…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Xiaoyi Wen , Fei Jiang

Purpose: Deep learning methods have shown promising results in the segmentation, and detection of diseases in medical images. However, most methods are trained and tested on data from a single source, modality, organ, or disease type,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Nchongmaje Ndipenocha , Alina Mirona , Kezhi Wanga , Yongmin Li

Deep learning-based image manipulation localization (IML) methods have achieved remarkable performance in recent years, but typically rely on large-scale pixel-level annotated datasets. To address the challenge of acquiring high-quality…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Songlin Li , Guofeng Yu , Zhiqing Guo , Yunfeng Diao , Dan Ma , Gaobo Yang

We present a method combining affinity prediction with region agglomeration, which improves significantly upon the state of the art of neuron segmentation from electron microscopy (EM) in accuracy and scalability. Our method consists of a…

Computer Vision and Pattern Recognition · Computer Science 2020-07-29 Jan Funke , Fabian David Tschopp , William Grisaitis , Arlo Sheridan , Chandan Singh , Stephan Saalfeld , Srinivas C. Turaga

Objectives Parametric tissue mapping enables quantitative cardiac tissue characterization but is limited by inter-observer variability during manual delineation. Traditional approaches relying on average relaxation values and single cutoffs…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Andreea Bianca Popescu , Andreas Seitz , Heiko Mahrholdt , Jens Wetzl , Athira Jacob , Lucian Mihai Itu , Constantin Suciu , Teodora Chitiboi

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Xianrui Li , Yufei Cui , Jun Li , Antoni B. Chan

Image registration is a widely-used technique in analysing large scale datasets that are captured through various imaging modalities and techniques in biomedical imaging such as MRI, X-Rays, etc. These datasets are typically collected from…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Hassan Mahmood , Asim Iqbal , Syed Mohammed Shamsul Islam

In actual industrial production, the assessment of the steel plate welding effect is an important task, and the segmentation of the weld section is the basis of the assessment. This paper proposes an industrial weld segmentation network…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Qi Wang , Jingwu Mei

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

Automating Multiple Sclerosis (MS) lesion segmentation would be of great benefit in initial diagnosis as well as monitoring disease progression. Deep learning based segmentation models perform well in many domains, but the state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Liviu Badea , Maria Popa

The purpose was to assess the clinical value of a novel DropOut model for detecting and segmenting brain metastases, in which a neural network is trained on four distinct MRI sequences using an input dropout layer, thus simulating the…

Recent advances in deep learning algorithms have led to significant benefits for solving many medical image analysis problems. Training deep learning models commonly requires large datasets with expert-labeled annotations. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Stephanie Wichuk , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Detecting out-of-distribution (OOD) samples is crucial for trustworthy AI in real-world applications. Leveraging recent advances in representation learning and latent embeddings, Various scoring algorithms estimate distributions beyond the…

Machine Learning · Computer Science 2024-09-20 Jeng-Lin Li , Ming-Ching Chang , Wei-Chao Chen
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