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Robins (1998) introduced marginal structural models (MSMs), a general class of counterfactual models for the joint effects of time-varying treatment regimes in complex longitudinal studies subject to time-varying confounding. He established…

Methodology · Statistics 2018-09-17 Eric J Tchetgen Tchetgen , Haben Michael , Yifan Cui

The current literature regarding generation of complex, realistic synthetic tabular data, particularly for randomized controlled trials (RCTs), often ignores missing data. However, missing data are common in RCT data and often are not…

Other Statistics · Statistics 2025-12-02 Niki Z. Petrakos , Erica E. M. Moodie , Nicolas Savy

We consider identification and estimation with an outcome missing not at random (MNAR). We study an identification strategy based on a so-called shadow variable. A shadow variable is assumed to be correlated with the outcome, but…

Methodology · Statistics 2019-09-10 Wang Miao , Lan Liu , Eric Tchetgen Tchetgen , Zhi Geng

Data imputation is a cornerstone technique for handling missing values in real-world datasets, which are often plagued by missingness. Despite recent progress, prior studies on Large Language Models-based imputation remain limited by…

Machine Learning · Computer Science 2026-03-25 Arthur Dantas Mangussi , Ricardo Cardoso Pereira , Ana Carolina Lorena , Pedro Henriques Abreu

When a missing-data mechanism is NMAR or non-ignorable, missingness is itself vital information and it must be taken into the likelihood, which, however, needs to introduce additional parameters to be estimated. The incompleteness of the…

Methodology · Statistics 2014-05-15 Kosuke Morikawa , Yutaka Kano

Constant (naive) imputation is still widely used in practice as this is a first easy-to-use technique to deal with missing data. Yet, this simple method could be expected to induce a large bias for prediction purposes, as the imputed input…

Statistics Theory · Mathematics 2024-02-07 Alexis Ayme , Claire Boyer , Aymeric Dieuleveut , Erwan Scornet

We introduce multiple hidden Markov models (MHMMs) where an observed multivariate categorical time series depends on an unobservable multivariate Mar- kov chain. MHMMs provide an elegant framework for specifying various independence…

Methodology · Statistics 2013-09-17 Roberto Colombi , Sabrina Giordano

Missing data is common in applied data science, particularly for tabular data sets found in healthcare, social sciences, and natural sciences. Most supervised learning methods only work on complete data, thus requiring preprocessing such as…

Machine Learning · Computer Science 2023-10-25 Mike Van Ness , Tomas M. Bosschieter , Roberto Halpin-Gregorio , Madeleine Udell

Handling missing data is a major challenge in model-based clustering, especially when the data exhibit skewness and heavy tails. We address this by extending the finite mixture of scale mixtures of multivariate skew-normal (FMSMSN) family…

Methodology · Statistics 2025-07-29 Jason Pillay , Cristina Tortora , Antonio Punzo , Andriette Bekker

Missing data may be disastrous for the identifiability of causal and statistical estimands. In graphical missing data models, colluders are dependence structures that have a special importance for identification considerations. It has been…

Methodology · Statistics 2024-07-04 Santtu Tikka , Juha Karvanen

Structural-equations models (SEMs) are perhaps the most commonly used framework for modeling causality. However, as we show, naively extending this framework to infinitely many variables, which is necessary, for example, to model dynamical…

Artificial Intelligence · Computer Science 2021-12-20 Spencer Peters , Joseph Y. Halpern

Deep Learning (DL) methods have dramatically increased in popularity in recent years, with significant growth in their application to supervised learning problems in the biomedical sciences. However, the greater prevalence and complexity of…

Machine Learning · Statistics 2023-10-30 David K Lim , Naim U Rashid , Junier B Oliva , Joseph G Ibrahim

Structural causal models (SCMs) are a powerful tool for understanding the complex causal relationships that underlie many real-world systems. As these systems grow in size, the number of variables and complexity of interactions between them…

Artificial Intelligence · Computer Science 2023-10-13 Moritz Willig , Matej Zečević , Devendra Singh Dhami , Kristian Kersting

Multivariate spatio-temporal data arise more and more frequently in a wide range of applications; however, there are relatively few general statistical methods that can readily use that incorporate spatial, temporal and variable…

Methodology · Statistics 2017-11-15 Elynn Yi Chen , Qiwei Yao , Rong Chen

We offer a natural and extensible measure-theoretic treatment of missingness at random. Within the standard missing data framework, we give a novel characterisation of the observed data as a stopping-set sigma algebra. We demonstrate that…

Methodology · Statistics 2018-01-23 Daniel Farewell , Rhian Daniel , Shaun Seaman

Longitudinal data are characterized by the dependence between observations coming from the same individual. In a regression perspective, such a dependence can be usefully ascribed to unobserved features (covariates) specific to each…

Methodology · Statistics 2015-09-07 Maria Francesca Marino , Marco Alfó

An approach to amputation, the process of introducing missing values to a complete dataset, is presented. It allows to construct missingness indicators in a flexible and principled way via copulas and Bernoulli margins and to incorporate…

Applications · Statistics 2025-07-28 Marius Hofert , James Jackson , Niels Hagenbuch

Existing methods for differentiable structure learning in discrete data typically assume that the data are generated from specific structural equation models. However, these assumptions may not align with the true data-generating process,…

Machine Learning · Computer Science 2025-10-28 Chang Deng , Bryon Aragam

Causal structure learning with data from multiple contexts carries both opportunities and challenges. Opportunities arise from considering shared and context-specific causal graphs enabling to generalize and transfer causal knowledge across…

Machine Learning · Computer Science 2024-10-29 Martin Rabel , Wiebke Günther , Jakob Runge , Andreas Gerhardus

We present a framework for generating multiple imputations for continuous data when the missing data mechanism is unknown. Imputations are generated from more than one imputation model in order to incorporate uncertainty regarding the…

Applications · Statistics 2013-01-14 Juned Siddique , Ofer Harel , Catherine M. Crespi