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Calculating the molecular ground-state energy is a central challenge in computational chemistry. Conventional methods such as the Complete Active Space Configuration Interaction scale exponentially with molecular size, limiting their…

Quantum Physics · Physics 2025-12-15 Stefano Bruni , Enrico Prati

This article consists of a short introduction to the quantum approximation optimisation algorithm (QAOA). The mathematical structure of the QAOA, as well as its basic properties, are described. The implementation of the QAOA on MaxCut…

Quantum Physics · Physics 2021-03-25 Behzad Mansouri

One of the most common problem-solving heuristics is by analogy. For a given problem, a solver can be viewed as a strategic walk on its fitness landscape. Thus if a solver works for one problem instance, we expect it will also be effective…

Machine Learning · Computer Science 2023-12-06 Mingyu Huang , Ke Li

The classical homotopy optimization approach has the potential to deal with highly nonlinear landscape, such as the energy landscape of QAOA problems. Following this motivation, we introduce Hamiltonian-Oriented Homotopy QAOA (HOHo-QAOA),…

Quantum Physics · Physics 2023-01-31 Akash Kundu , Ludmila Botelho , Adam Glos

In black-box combinatorial optimization, objective evaluations are often expensive, so high quality solutions must be found under a limited budget. Factorization machine with quantum annealing (FMQA) builds a quadratic surrogate model from…

Machine Learning · Computer Science 2026-02-11 Tetsuro Abe , Masashi Yamashita , Shu Tanaka

Calculating the energy spectrum of a quantum system is an important task, for example to analyse reaction rates in drug discovery and catalysis. There has been significant progress in developing algorithms to calculate the ground state…

Quantum Physics · Physics 2019-06-12 Suguru Endo , Tyson Jones , Sam McArdle , Xiao Yuan , Simon Benjamin

Variational methods play an important role in the study of quantum many-body problems, both in the flavor of classical variational principles based on tensor networks as well as of quantum variational principles in near-term quantum…

Quantum Physics · Physics 2026-02-18 J. Eisert

Combinatorial optimization problems can be mapped onto Ising models, and their ground state is generally difficult to find. A lot of heuristics for these problems have been proposed, and one promising approach is to use continuous…

Statistical Mechanics · Physics 2022-11-03 Shintaro Sato

This work explores the global optimization problem of finding lowest-energy configurations (ground states) in disordered continuous spins models from statistical physics, with a particular focus on the random field XY model. Due to an…

Optimization and Control · Mathematics 2026-05-07 Ramgopal Agrawal , Lorenzo Ciarpaglini , Enzo Marinari , Marco Sciandrone , Diego Scuppa , Elisa Trasatti

Recent hardware advances in quantum and quantum-inspired annealers promise substantial speedup for solving NP-hard combinatorial optimization problems compared to general-purpose computers. These special-purpose hardware are built for…

Quantum Physics · Physics 2020-01-06 Avradip Mandal , Arnab Roy , Sarvagya Upadhyay , Hayato Ushijima-Mwesigwa

Local search is widely used to solve combinatorial optimisation problems and to model biological evolution, but the performance of local search algorithms on different kinds of fitness landscapes is poorly understood. Here we consider how…

Data Structures and Algorithms · Computer Science 2020-11-13 Artem Kaznatcheev , David A. Cohen , Peter G. Jeavons

Binary optimisation tasks are ubiquitous in areas ranging from logistics to cryptography. The exponential complexity of such problems means that the performance of traditional computational methods decreases rapidly with increasing problem…

Quantum annealers are an alternative approach to quantum computing which make use of the adiabatic theorem to efficiently find the ground state of a physically realizable Hamiltonian. Such devices are currently commercially available and…

Quantum Physics · Physics 2021-02-24 Justin Copenhaver , Adam Wasserman , Birgit Wehefritz-Kaufmann

Estimating the ground-state energy of Hamiltonians is a fundamental task for which it is believed that quantum computers can be helpful. Several approaches have been proposed toward this goal, including algorithms based on quantum phase…

Quantum Physics · Physics 2025-11-26 Dhrumil Patel , Daniel Koch , Saahil Patel , Mark M. Wilde

Quantum computers and simulators may offer significant advantages over their classical counterparts, providing insights into quantum many-body systems and possibly improving performance for solving exponentially hard problems, such as…

The optimization of Variational Quantum Eigensolver is severely challenged by finite-shot sampling noise, which distorts the cost landscape, creates false variational minima, and induces statistical bias called winner's curse. We…

Quantum Physics · Physics 2025-11-12 Vojtěch Novák , Silvie Illésová , Tomáš Bezděk , Ivan Zelinka , Martin Beseda

We use matrix product techniques to investigate the performance of two algorithms for obtaining the ground state of a quantum many-body Hamiltonian $H = H_A + H_B$ in infinite systems. The first algorithm is a generalization of the quantum…

Strongly Correlated Electrons · Physics 2022-11-30 Ruoshui Wang , Timothy H. Hsieh , Guifre Vidal

Anticipating the low energy arrangements of atoms in space is an indispensable scientific task. Modern stochastic approaches to searching for these configurations depend on the optimisation of structures to nearby local minima in the energy…

Materials Science · Physics 2019-02-07 Chris J. Pickard

We suggest an iterative quantum protocol, allowing to solve optimization problems with a glassy energy landscape. It is based on a periodic cycling around the tricritical point of the many-body localization transition. This ensures that…

Quantum Physics · Physics 2022-09-21 Hanteng Wang , Hsiu-Chung Yeh , Alex Kamenev

One of the main limitations of variational quantum algorithms is the classical optimization of the highly dimensional non-convex variational parameter landscape. To simplify this optimization, we can reduce the search space using problem…

Quantum Physics · Physics 2025-08-28 Isak Lyngfelt , Laura García-Álvarez
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