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We show that simple stochastic models of genome evolution lead to power law asymptotics of protein domain family size distribution. These models, called Birth, Death and Innovation Models (BDIM), represent a special class of balanced…

Genomics · Quantitative Biology 2007-05-23 Georgy P. Karev , Yuri I. Wolf , Eugene V. Koonin

Latent variable models for text, when trained successfully, accurately model the data distribution and capture global semantic and syntactic features of sentences. The prominent approach to train such models is variational autoencoders…

Machine Learning · Computer Science 2021-06-09 Bo Pang , Erik Nijkamp , Tian Han , Ying Nian Wu

Demographic models built from genetic data play important roles in illuminating prehistorical events and serving as null models in genome scans for selection. We introduce an inference method based on the joint frequency spectrum of genetic…

Populations and Evolution · Quantitative Biology 2010-05-10 Ryan N. Gutenkunst , Ryan D. Hernandez , Scott H. Williamson , Carlos D. Bustamante

We provide a complete description of possible covariance matrices consistent with a Gaussian latent tree model for any tree. We then present techniques for utilising these constraints to assess whether observed data is compatible with that…

Methodology · Statistics 2016-04-13 Nathaniel Shiers , Piotr Zwiernik , John A. D. Aston , Jim Q. Smith

We study the spatio-temporal prediction problem, which has attracted the attention of many researchers due to its critical real-life applications. In particular, we introduce a novel approach to this problem. Our approach is based on the…

Machine Learning · Statistics 2020-07-07 Oguzhan Karaahmetoglu , Suleyman Serdar Kozat

Understanding temporal dynamics in medical imaging is crucial for applications such as disease progression modeling, treatment planning and anatomical development tracking. However, most deep learning methods either consider only single…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Nico Albert Disch , Yannick Kirchhoff , Robin Peretzke , Maximilian Rokuss , Saikat Roy , Constantin Ulrich , David Zimmerer , Klaus Maier-Hein

There have been many studies to examine whether one trait is correlated with another trait across a group of present-day species (for example, do species with larger brains tend to have longer gestation times. Since the introduction of the…

Populations and Evolution · Quantitative Biology 2023-09-07 Albert Ch. Soewongsono , Barbara R. Holland , Malgorzata M. O'Reilly

For a class of processes modeling the evolution of a spatially structured population with migration and a logistic local regulation of the reproduction dynamics, we show convergence to an upper invariant measure from a suitable class of…

Probability · Mathematics 2011-01-04 M. Hutzenthaler , A. Wakolbinger

Persistent homology is a cornerstone of topological data analysis, offering a multiscale summary of topology with robustness to nuisance transformations, such as rotations and small deformations. Persistent homology has seen broad use…

Methodology · Statistics 2025-11-19 Zitian Wu , Arkaprava Roy , Leo L. Duan

Characterizing the relationship between neural population activity and behavioral data is a central goal of neuroscience. While latent variable models (LVMs) are successful in describing high-dimensional time-series data, they are typically…

Machine Learning · Computer Science 2026-02-12 Rabia Gondur , Usama Bin Sikandar , Evan Schaffer , Mikio Christian Aoi , Stephen L Keeley

We survey recent developments about random real trees, whose prototype is the Continuum Random Tree (CRT) introduced by Aldous in 1991. We briefly explain the formalism of real trees, which yields a neat presentation of the theory and in…

Probability · Mathematics 2007-05-23 J. F. Le Gall

The goal of these lectures is to review some mathematical aspects of random tree models used in evolutionary biology to model gene trees or species trees. We start with stochastic models of tree shapes (finite trees without edge lengths),…

Probability · Mathematics 2017-08-30 Amaury Lambert

We propose a spatio-temporal data-fusion framework for point data and gridded data with variables observed on different spatial supports. A latent Gaussian field with a Mat\'ern-SPDE prior provides a continuous space representation, while…

Methodology · Statistics 2025-11-19 Weiyue Zheng , Andrew Elliott , Claire Miller , Marian Scott

Non-spherical particles transported by an anisotropic turbulent flow preferentially align with the mean shear and intermittently tumble when the local strain fluctuates. Such an intricate behaviour is here studied for inertialess,…

Soft Condensed Matter · Physics 2022-12-27 Lorenzo Campana , Mireille Bossy , Jeremie Bec

Prediction is a classic challenge in spatial statistics and the inclusion of spatial covariates can greatly improve predictive performance when incorporated into a model with latent spatial effects. It is desirable to develop flexible…

Methodology · Statistics 2025-02-24 Alex Ziyu Jiang , Jon Wakefield

1.) Spatio-temporal datasets that are difficult to analyze are common in ecological surveys. There are software packages available to analyze these datasets, but many of them require advanced coding skills. There is a growing need for easy…

Methodology · Statistics 2021-10-07 Ethan Lawler , Chris Field , Joanna Mills Flemming

Consider a one-dimensional stepping stone model with colonies of size $M$ and per-generation migration probability $\nu$, or a voter model on $\mathbb{Z}$ in which interactions occur over a distance of order $K$. Sample one individual at…

Probability · Mathematics 2008-01-28 Richard Durrett , Mateo Restrepo

In many biological systems, motile agents exhibit random motion with short-term directional persistence, together with crowding effects arising from spatial exclusion. We formulate and study a class of lattice-based models for multiple…

Biological Physics · Physics 2019-11-06 Stephen Zhang , Aaron Chong , Barry D. Hughes

The paper was suggested by a brief note of the second author about the application of the Hubbert curve to predict decay of resource exploitation. A further suggestion came from the interpretation of the Hubbert curve in terms of a specific…

Populations and Evolution · Quantitative Biology 2022-09-07 Enrico Canuto , Daniele Mazza

Long Short-Term Memory (LSTM) has achieved state-of-the-art performances on a wide range of tasks. Its outstanding performance is guaranteed by the long-term memory ability which matches the sequential data perfectly and the gating…

Neural and Evolutionary Computing · Computer Science 2019-01-29 Shiwei Liu , Decebal Constantin Mocanu , Mykola Pechenizkiy