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Multi-instance learning is a type of weakly supervised learning. It deals with tasks where the data is a set of bags and each bag is a set of instances. Only the bag labels are observed whereas the labels for the instances are unknown. An…

Machine Learning · Computer Science 2021-05-05 Weijia Zhang

Unsupervised feature learning has made great strides with contrastive learning based on instance discrimination and invariant mapping, as benchmarked on curated class-balanced datasets. However, natural data could be highly correlated and…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Xudong Wang , Ziwei Liu , Stella X. Yu

Histopathology image analysis can be considered as a Multiple instance learning (MIL) problem, where the whole slide histopathology image (WSI) is regarded as a bag of instances (i.e, patches) and the task is to predict a single class label…

Computer Vision and Pattern Recognition · Computer Science 2019-06-28 Meng Li , Lin Wu , Arnold Wiliem , Kun Zhao , Teng Zhang , Brian C. Lovell

In Multiple Instance Learning (MIL), models are trained using bags of instances, where only a single label is provided for each bag. A bag label is often only determined by a handful of key instances within a bag, making it difficult to…

Machine Learning · Computer Science 2022-03-16 Joseph Early , Christine Evers , Sarvapali Ramchurn

Weakly supervised instance segmentation (WSIS) using only image-level labels is a challenging task due to the difficulty of aligning coarse annotations with the finer task. However, with the advancement of deep neural networks (DNNs), WSIS…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Zecheng Li , Zening Zeng , Yuqi Liang , Jin-Gang Yu

Object category localization is a challenging problem in computer vision. Standard supervised training requires bounding box annotations of object instances. This time-consuming annotation process is sidestepped in weakly supervised…

Computer Vision and Pattern Recognition · Computer Science 2016-05-30 Ramazan Gokberk Cinbis , Jakob Verbeek , Cordelia Schmid

This paper presents the first attempt to learn semantic boundary detection using image-level class labels as supervision. Our method starts by estimating coarse areas of object classes through attentions drawn by an image classification…

Computer Vision and Pattern Recognition · Computer Science 2022-12-16 Namyup Kim , Sehyun Hwang , Suha Kwak

Contrastive learning is a well-established paradigm in representation learning. The standard framework of contrastive learning minimizes the distance between "similar" instances and maximizes the distance between dissimilar ones in the…

Machine Learning · Computer Science 2025-02-06 Naghmeh Ghanooni , Barbod Pajoum , Harshit Rawal , Sophie Fellenz , Vo Nguyen Le Duy , Marius Kloft

Recent advancements in computational pathology and artificial intelligence have significantly improved whole slide image (WSI) classification. However, the gigapixel resolution of WSIs and the scarcity of manual annotations present…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Mingxi Ouyang , Yuqiu Fu , Renao Yan , ShanShan Shi , Xitong Ling , Lianghui Zhu , Yonghong He , Tian Guan

Weakly supervised object detection (WSOD) is a challenging task when provided with image category supervision but required to simultaneously learn object locations and object detectors. Many WSOD approaches adopt multiple instance learning…

Computer Vision and Pattern Recognition · Computer Science 2019-04-12 Fang Wan , Chang Liu , Wei Ke , Xiangyang Ji , Jianbin Jiao , Qixiang Ye

In whole slide images (WSIs) analysis, attention-based multi-instance learning (MIL) models are susceptible to spurious correlations and degrade under domain shift. These methods may assign high attention weights to non-tumor regions, such…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Xin Liu , Weijia Zhang , Wei Tang , Thuc Duy Le , Jiuyong Li , Lin Liu , Min-Ling Zhang

Multiple Instance Learning (MIL) has garnered widespread attention in the field of Whole Slide Image (WSI) classification as it replaces pixel-level manual annotation with diagnostic reports as labels, significantly reducing labor costs.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Tianhang Nan , Hao Quan , Yong Ding , Xingyu Li , Kai Yang , Xiaoyu Cui

Multimodal image-tabular learning is gaining attention, yet it faces challenges due to limited labeled data. While earlier work has applied self-supervised learning (SSL) to unlabeled data, its task-agnostic nature often results in learning…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Siyi Du , Xinzhe Luo , Declan P. O'Regan , Chen Qin

In-line with the success of deep learning on traditional recognition problem, several end-to-end deep models for zero-shot recognition have been proposed in the literature. These models are successful to predict a single unseen label given…

Computer Vision and Pattern Recognition · Computer Science 2018-03-19 Shafin Rahman , Salman Khan

Contrastive Language-Image Pretraining (CLIP) achieves strong generalization in vision-language tasks by aligning images and texts in a shared embedding space. However, recent findings show that CLIP-like models still underutilize…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Weiheng Zhao , Zilong Huang , Jiashi Feng , Xinggang Wang

Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu

While multiple instance learning (MIL) has shown to be a promising approach for histopathological whole slide image (WSI) analysis, its reliance on permutation invariance significantly limits its capacity to effectively uncover semantic…

Image and Video Processing · Electrical Eng. & Systems 2025-07-14 Xiwen Chen , Peijie Qiu , Wenhui Zhu , Hao Wang , Huayu Li , Xuanzhao Dong , Xiaotong Sun , Xiaobing Yu , Yalin Wang , Abolfazl Razi , Aristeidis Sotiras

Multi-instance learning (MIL) has a wide range of applications due to its distinctive characteristics. Although many state-of-the-art algorithms have achieved decent performances, a plurality of existing methods solve the problem only in…

Machine Learning · Statistics 2015-12-04 Hanqiang Song , Zhuotun Zhu , Xinggang Wang

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Unsupervised person re-identification (ReID) aims at learning discriminative identity features without annotations. Recently, self-supervised contrastive learning has gained increasing attention for its effectiveness in unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2021-08-19 Hao Chen , Benoit Lagadec , Francois Bremond