Related papers: Evaluating AI systems under uncertain ground truth…
Although deep learning (DL) models have shown great success in many medical image analysis tasks, deployment of the resulting models into real clinical contexts requires: (1) that they exhibit robustness and fairness across different…
Medicine is rife with high-stakes uncertainty. Doctors routinely make clinical judgments and decisions that juggle many fundamental unknowns, like predictions about what might be causing a patients' symptoms or decisions about what…
Background: Evaluating AI-generated treatment plans is a key challenge as AI expands beyond diagnostics, especially with new reasoning models. This study compares plans from human experts and two AI models (a generalist and a reasoner),…
Artificial intelligence in medicine is built to serve the average patient. By minimizing error across large datasets, most systems deliver strong aggregate accuracy yet falter at the margins: patients with rare variants, multimorbidity, or…
Deep learning has played a major role in the interpretation of dermoscopic images for detecting skin defects and abnormalities. However, current deep learning solutions for dermatological lesion analysis are typically limited in providing…
The ethical integration of Artificial Intelligence (AI) in healthcare necessitates addressing fairness-a concept that is highly context-specific across medical fields. Extensive studies have been conducted to expand the technical components…
While artificial intelligence (AI) holds promise for supporting healthcare providers and improving the accuracy of medical diagnoses, a lack of transparency in the composition of datasets exposes AI models to the possibility of…
Machine learning (ML) systems for medical imaging have demonstrated remarkable diagnostic capabilities, but their susceptibility to biases poses significant risks, since biases may negatively impact generalization performance. In this…
The AI act is the European Union-wide regulation of AI systems. It includes specific provisions for general-purpose AI models which however need to be further interpreted in terms of technical standards and state-of-art studies to ensure…
Adversarial attacks pose a severe risk to AI systems used in healthcare, capable of misleading models into dangerous misclassifications that can delay treatments or cause misdiagnoses. These attacks, often imperceptible to human perception,…
In recent years the development of artificial intelligence (AI) systems for automated medical image analysis has gained enormous momentum. At the same time, a large body of work has shown that AI systems can systematically and unfairly…
The full acceptance of Deep Learning (DL) models in the clinical field is rather low with respect to the quantity of high-performing solutions reported in the literature. Particularly, end users are reluctant to rely on the rough…
Medical AI algorithms can often experience degraded performance when evaluated on previously unseen sites. Addressing cross-site performance disparities is key to ensuring that AI is equitable and effective when deployed on diverse patient…
Before deploying an AI system to replace an existing process, it must be compared with the incumbent to ensure improvement without added risk. Traditional evaluation relies on ground truth for both systems, but this is often unavailable due…
The growing integration of large language models across professional domains transforms how experts make critical decisions in healthcare, education, and law. While significant research effort focuses on getting these systems to communicate…
Uncertainty is a fundamental challenge in medical practice, but current medical AI systems fail to explicitly quantify or communicate uncertainty in a way that aligns with clinical reasoning. Existing XAI works focus on interpreting model…
A well-known limitation of AI systems is presumptuousness: the tendency of AI systems to provide confident answers when information may be lacking. This challenge is particularly acute in legal applications, where a core task for attorneys,…
A clinical artificial intelligence (AI) system is often validated on a held-out set of data which it has not been exposed to before (e.g., data from a different hospital with a distinct electronic health record system). This evaluation…
Performance comparisons are fundamental in medical imaging Artificial Intelligence (AI) research, often driving claims of superiority based on relative improvements in common performance metrics. However, such claims frequently rely solely…
When deploying machine learning models in high-stakes real-world environments such as health care, it is crucial to accurately assess the uncertainty concerning a model's prediction on abnormal inputs. However, there is a scarcity of…