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There has been a wide interest to extend univariate and multivariate nonparametric procedures to clustered and hierarchical data. Traditionally, parametric mixed models have been used to account for the correlation structures among the…

Statistics Theory · Mathematics 2018-03-02 Jaakko Nevalainen , Denis Larocque , Hannu Oja , Ilkka Pörsti

We develop nested variational inference (NVI), a family of methods that learn proposals for nested importance samplers by minimizing an forward or reverse KL divergence at each level of nesting. NVI is applicable to many commonly-used…

Machine Learning · Statistics 2021-06-22 Heiko Zimmermann , Hao Wu , Babak Esmaeili , Jan-Willem van de Meent

Motivated by the problem of accurately predicting gap times between successive blood donations, we present here a general class of Bayesian nonparametric models for clustering. These models allow for prediction of new recurrences,…

Methodology · Statistics 2022-10-18 Raffaele Argiento , Riccardo Corradin , Alessandra Guglielmi , Ettore Lanzarone

Functional Magnetic Resonance Imaging~(fMRI) is widely used to study activation in the human brain. In most cases, data are commonly used to construct activation maps corresponding to a given paradigm. Results can be very variable, hence…

Applications · Statistics 2022-05-04 Ranjan Maitra

A novel non-parametric estimator of the correlation between grouped measurements of a quantity is proposed in the presence of noise. This work is primarily motivated by functional brain network construction from fMRI data, where brain…

Methodology · Statistics 2023-02-16 Hanâ Lbath , Alexander Petersen , Wendy Meiring , Sophie Achard

Stochastic planning can be reduced to probabilistic inference in large discrete graphical models, but hardness of inference requires approximation schemes to be used. In this paper we argue that such applications can be disentangled along…

Artificial Intelligence · Computer Science 2022-09-05 Zhennan Wu , Roni Khardon

Contrastive learning have been widely used as pretext tasks for self-supervised pre-trained molecular representation learning models in AI-aided drug design and discovery. However, exiting methods that generate molecular views by…

Biomolecules · Quantitative Biology 2023-03-14 Ziqiao Zhang , Ailin Xie , Jihong Guan , Shuigeng Zhou

Bayesian nonparametric methods are a popular choice for analysing survival data due to their ability to flexibly model the distribution of survival times. These methods typically employ a nonparametric prior on the survival function that is…

Methodology · Statistics 2022-02-22 Edwin Fong , Brieuc Lehmann

Diffusion magnetic resonance imaging (MRI) has revealed important insights into white matter microstructure, but its application to gray matter remains comparatively less explored. Here, we investigate whether global patterns of gray-matter…

Quantitative Methods · Quantitative Biology 2026-04-13 Lucas Z. Brito , Ryan P. Cabeen , David H. Laidlaw

Functional principal component analysis has been shown to be invaluable for revealing variation modes of longitudinal outcomes, which serves as important building blocks for forecasting and model building. Decades of research have advanced…

Methodology · Statistics 2024-10-07 Peijun Sang , Dehan Kong , Shu Yang

Mendelian randomization (MR) is widely used to uncover causal relationships in the presence of unmeasured confounders. However, most existing MR methods presuppose linear causality, risking bias when the true relationships are nonlinear,…

Methodology · Statistics 2025-08-05 Xinpei Wang , Tao Huang , Jinzhu Jia

We develop a general analytical and numerical framework for estimating intra- and extra-neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion, in each imaging voxel. By employing a set of rotational…

Biological Physics · Physics 2018-04-10 Dmitry S. Novikov , Jelle Veraart , Ileana O. Jelescu , Els Fieremans

High-resolution functional imaging is providing increasingly rich measurements of brain activity in animals and humans. A major challenge is to leverage such data to gain insight into the brain's computational mechanisms. The first step is…

Neurons and Cognition · Quantitative Biology 2016-08-09 Nikolaus Kriegeskorte , Jörn Diedrichsen

The proliferation of computing devices has brought about an opportunity to deploy machine learning models on new problem domains using previously inaccessible data. Traditional algorithms for training such models often require data to be…

Recent technology and equipment advancements provide with us opportunities to better analyze Alzheimer's disease (AD), where we could collect and employ the data from different image and genetic modalities that may potentially enhance the…

Machine Learning · Computer Science 2023-03-09 Kai Liu , Yarui Cao

Magnetic resonance imaging (MRI) is a non-invasive medical imaging technique offering high-resolution 3D images and valuable insights into human tissue conditions. Even at present, the refinement of denoising methods for MRI remains a…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Shiao Li

Percentile-based approaches have been proposed as a non-parametric alternative to parametric central-tendency statistics to normalize observed citation counts. Percentiles are based on an ordered set of citation counts in a reference set,…

Digital Libraries · Computer Science 2013-09-18 Lutz Bornmann , Loet Leydesdorff , Jian Wang

Feature extraction is a method of capturing visual content of an image. The feature extraction is the process to represent raw image in its reduced form to facilitate decision making such as pattern classification. We have tried to address…

Computer Vision and Pattern Recognition · Computer Science 2012-08-13 V. P. Gladis Pushpa Rathi , S. Palani

Functional MRI (fMRI) has become the most common method for investigating the human brain. However, fMRI data present some complications for statistical analysis and modeling. One recently developed approach to these data focuses on…

Applications · Statistics 2015-03-19 Vincent Q. Vu , Pradeep Ravikumar , Thomas Naselaris , Kendrick N. Kay , Jack L. Gallant , Bin Yu

For linear regression models with cross-section or panel data, it is natural to assume that the disturbances are clustered in two dimensions. However, the finite-sample properties of two-way cluster-robust tests and confidence intervals are…

Econometrics · Economics 2026-03-13 James G. MacKinnon , Morten Ørregaard Nielsen , Matthew D. Webb