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Natural products, as metabolites from microorganisms, animals, or plants, exhibit diverse biological activities, making them crucial for drug discovery. Nowadays, existing deep learning methods for natural products research primarily rely…

Quantitative Methods · Quantitative Biology 2026-05-11 Yuheng Ding , Bo Qiang , Shaoning Li , Yiran Zhou , Jie Yu , Qi Li , Cheng Shi , Liangren Zhang , Yusong Wang , Nanning Zheng , Zhenming Liu

Machine Learning (ML) and Deep Learning (DL) based framework have evolved rapidly and generated considerable interests for predicting the properties of materials. In this work, we utilize ML-DL framework to predict the electrochemical…

Machine learning is a powerful approach for fitting microstructural models to diffusion MRI data. Early machine learning microstructure imaging implementations trained regressors to estimate model parameters in a supervised way, using…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Jason P. Lim , Stefano B. Blumberg , Neil Narayan , Sean C. Epstein , Daniel C. Alexander , Marco Palombo , Paddy J. Slator

The impressive performance of deep learning architectures is associated with a massive increase in model complexity. Millions of parameters need to be tuned, with training and inference time scaling accordingly, together with energy…

Machine Learning · Computer Science 2023-11-10 Paolo Didier Alfano , Vito Paolo Pastore , Lorenzo Rosasco , Francesca Odone

Complex data mining has wide application value in many fields, especially in the feature extraction and classification tasks of unlabeled data. This paper proposes an algorithm based on self-supervised learning and verifies its…

Machine Learning · Computer Science 2025-04-08 Yingbin Liang , Lu Dai , Shuo Shi , Minghao Dai , Junliang Du , Haige Wang

Self-supervised learning (SSL) methods such as masked language modeling have shown massive performance gains by pretraining transformer models for a variety of natural language processing tasks. The follow-up research adapted similar…

Computer Vision and Pattern Recognition · Computer Science 2022-05-12 Gokul Karthik Kumar , Sahal Shaji Mullappilly , Abhishek Singh Gehlot

Self-supervised learning, which is strikingly referred to as the dark matter of intelligence, is gaining more attention in biomedical applications of deep learning. In this work, we introduce a novel self-supervision objective for the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Royden Wagner , Carlos Fernandez Lopez , Christoph Stiller

Machine learning models are exceptionally effective in capturing complex non-linear relationships of high-dimensional datasets and making accurate predictions. However, their intrinsic ``black-box'' nature makes it difficult to interpret…

Plasma Physics · Physics 2024-07-29 Tadas Pyragius , Cary Colgan , Hazel Lowe , Filip Janky , Matteo Fontana , Yichen Cai , Graham Naylor

Simulating reactive dissolution of solid minerals in porous media has many subsurface applications, including carbon capture and storage (CCS), geothermal systems and oil & gas recovery. As traditional direct numerical simulators are…

Machine Learning · Computer Science 2025-12-16 Marcos Cirne , Hannah Menke , Alhasan Abdellatif , Julien Maes , Florian Doster , Ahmed H. Elsheikh

Understanding and predicting microstructure evolution is fundamental to materials science, as it governs the resulting properties and performance of materials. Traditional simulation methods, such as phase-field models, offer high-fidelity…

Machine Learning · Computer Science 2026-02-24 Michael Trimboli , Mohammed Alsubaie , Sirani M. Perera , Ke-Gang Wang , Xianqi Li

Quadrature by Expansion (QBX) is a quadrature method for approximating the value of the singular integrals encountered in the evaluation of layer potentials. It exploits the smoothness of the layer potential by forming locally-valid…

Numerical Analysis · Mathematics 2020-03-06 Matt Wala , Andreas Klöckner

Deep learning methods usually require a large amount of training data and lack interpretability. In this paper, we propose a novel knowledge distillation and model interpretation framework for medical image classification that jointly…

Computer Vision and Pattern Recognition · Computer Science 2022-01-13 Thanh Nguyen-Duc , He Zhao , Jianfei Cai , Dinh Phung

Score distillation sampling~(SDS) has been widely adopted to overcome the absence of unseen views in reconstructing 3D objects from a \textbf{single} image. It leverages pre-trained 2D diffusion models as teacher to guide the reconstruction…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Xuanyu Yi , Zike Wu , Qingshan Xu , Pan Zhou , Joo-Hwee Lim , Hanwang Zhang

Self-supervised learning methods have witnessed a recent surge of interest after proving successful in multiple application fields. In this work, we leverage these techniques, and we propose 3D versions for five different self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Aiham Taleb , Winfried Loetzsch , Noel Danz , Julius Severin , Thomas Gaertner , Benjamin Bergner , Christoph Lippert

Modern laboratory techniques like ultrafast laser excitation and shock compression can bring matter into highly nonequilibrium states with complex structural transformation, metallization and dissociation dynamics. To understand and model…

Computational Physics · Physics 2022-05-24 Qiyu Zeng , Bo Chen , Xiaoxiang Yu , Shen Zhang , Dongdong Kang , Han Wang , Jiayu Dai

Automated characterization of galactic substructure is an essential step in understanding the transformative physical processes driving galaxy evolution. In this study, we investigate the application of deep learning (DL) frameworks to…

Large Language Models (LLMs) have achieved remarkable success, underpinning diverse AI applications. However, they often suffer from performance degradation due to factors such as catastrophic forgetting during Supervised Fine-Tuning (SFT),…

Machine Learning · Computer Science 2026-04-20 Chi Liu , Xin Chen , Xu Zhou , Fangbo Tu , Srinivasan Manoharan

Deep neural networks have demonstrated promising performance on image recognition tasks. However, they may heavily rely on confounding factors, using irrelevant artifacts or bias within the dataset as the cue to improve performance. When a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Siyuan Yan , Zhen Yu , Xuelin Zhang , Dwarikanath Mahapatra , Shekhar S. Chandra , Monika Janda , Peter Soyer , Zongyuan Ge

Determining the stability of chemical compounds is essential for advancing material discovery. In this study, we introduce a novel deep neural network model designed to predict a crystal's formation energy, which identifies its stability…

Materials Science · Physics 2026-04-21 V. Torlao , E. A. Fajardo

The expansiveness of compositional phase space is too vast to fully search using current theoretical tools for many emergent problems in condensed matter physics. The reliance on a deep chemical understanding is one method to identify local…

Superconductivity · Physics 2023-01-26 Lazar Novakovic , Ashkan Salamat , Keith V. Lawler