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We investigate the dynamics of polymer translocation through a nanopore under an externally applied field using the 2D fluctuating bond model with single-segment Monte Carlo moves. We concentrate on the influence of the field strength $E$,…

Soft Condensed Matter · Physics 2011-08-26 Kaifu Luo , Ilkka Huopaniemi , Tapio Ala-Nissila , See-Chen Ying

In this work we study the noise induced effects on the dynamics of short polymers crossing a potential barrier, in the presence of a metastable state. An improved version of the Rouse model for a flexible polymer has been adopted to mimic…

Statistical Mechanics · Physics 2009-11-13 N. Pizzolato , A. Fiasconaro , B. Spagnolo

Using Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a circular nanocontainer through a nanopore under a driving force $F$. We observe that the translocation probability initially increases and then…

Soft Condensed Matter · Physics 2012-12-06 Kehong Zhang , Kaifu Luo

The transport of biomolecules across a cell membrane is an important phenomena that plays a pivotal role in the functioning of biological cells. In this paper, we investigate such processes by modeling the translocation of polymers through…

Soft Condensed Matter · Physics 2022-11-01 Andri Sharma

This paper studies the features of a homopolymer translocating through a flexible pore. The channel is modeled as a monolayer tube composed by monomers with two elastic parameters: spring-like two body interaction and bending three body…

Soft Condensed Matter · Physics 2022-11-01 A. Fiasconaro , G. Diez-Senorans , F. Falo

We perform two-dimensional Langevin dynamics simulations of electric-field driven polymer translocation through an attractive nanopore. We investigate the effect of the location of the attractive region using different pore patterns. This…

Soft Condensed Matter · Physics 2015-06-15 F Piguet , D P Foster

Single file translocation of a homopolymer through an active channel under the presence of a driving force is studied using Langevin dynamics simulation. It is shown that a channel with sticky walls and oscillating width could lead to…

Soft Condensed Matter · Physics 2013-02-01 Jack A. Cohen , Abhishek Chaudhuri , Ramin Golestanian

We present a numerical study of forced polymer translocation by using two separate pore models. Both of them have been extensively used in previous forced translocation studies. We show that variations in the pore model affect the forced…

Biological Physics · Physics 2015-05-19 V. V. Lehtola , K. Kaski , R. P. Linna

We investigate the influence of polymer-pore interactions on the translocation dynamics using Langevin dynamics simulations. An attractive interaction can greatly improve translocation probability. At the same time, it also increases…

Soft Condensed Matter · Physics 2007-10-01 Kaifu Luo , Tapio Ala-Nissila , See-chen Ying , Aniket Bhattacharya

We discuss multiscale simulations of long biopolymer translocation through wide nanopores that can accommodate multiple polymer strands. The simulations provide clear evidence of folding quantization, namely, the translocation proceeds…

Biological Physics · Physics 2009-11-13 Simone Melchionna , Massimo Bernaschi , Maria Fyta , Efthimios Kaxiras , Sauro Succi

We discuss the temporal distribution of dynamic processes in driven polymer transport inherent to flexible chains due to stochastic tension propagation. The stochasticity originates from the disordered initial configuration of an…

Soft Condensed Matter · Physics 2015-06-03 Takuya Saito , Takahiro Sakaue

We investigate the voltage-driven translocation of an inhomogeneously charged polymer through a nanopore by utilizing discrete and continuous stochastic models. As a simplified illustration of the effect of charge distribution on…

Soft Condensed Matter · Physics 2009-11-13 Aruna Mohan , Anatoly B. Kolomeisky , Matteo Pasquali

We investigate the driven polymer translocation through a nanometer-scale pore in the presence and absence of hydrodynamics both in good and bad solvent. We present our results on tension propagating along the polymer segment on the…

Biological Physics · Physics 2016-09-21 Jaakko E. Moisio , Joonas Piili , Riku P. Linna

Polymer translocation in crowded environments is a ubiquitous phenomenon in biological systems. We studied polymer translocation through a pore in free, one-sided (asymmetric), and two-sided (symmetric) crowded environments. Extensive…

Soft Condensed Matter · Physics 2024-03-01 Vrinda Garg , Rejoy Mathew , Riyan Ibrahim , Kulveer Singh , Surya K. Ghosh

Numerical results on the translocation of long biopolymers through mid-sized and wide pores are presented. The simulations are based on a novel methodology which couples molecular motion to a mesoscopic fluid solvent. Thousands of events of…

Biological Physics · Physics 2015-05-13 Maria Fyta , Simone Melchionna , Massimo Bernaschi , Efthimios Kaxiras , Sauro Succi

We review recent progress on the theory of dynamics of polymer translocation through a nanopore based on the iso-flux tension propagation (IFTP) theory. We investigate both pore-driven translocation of flexible and a semi-flexible polymers,…

Soft Condensed Matter · Physics 2018-10-16 Jalal Sarabadani , Tapio Ala-Nissila

We investigate the dynamics of pore-driven polymer translocation by theoretical analysis and molecular dynamics (MD) simulations. Using the tension propagation theory within the constant flux approximation we derive an explicit equation of…

Soft Condensed Matter · Physics 2015-06-23 Jalal Sarabadani , Timo Ikonen , Tapio Ala-Nissila

Polymer translocation is a promising strategy for the next-generation DNA sequencing technologies. The use of biological and synthetic nano-pores, however, still suffers from serious drawbacks. In particular, the width of the membrane layer…

Soft Condensed Matter · Physics 2017-11-30 Timothee Menais , Stefano Mossa , Arnaud Buhot

We present event distributions for the polymer translocation obtained by extensive Langevin dynamics simulations. Such distributions have not been reported previously and they provide new understanding of the stochastic characteristics of…

Soft Condensed Matter · Physics 2012-04-13 R. P. Linna , K. Kaski

We consider the translocation dynamics of a polymer chain forced through a nanopore by an external force on its head monomer on the trans side. For a proper theoretical treatment we generalize the iso-flux tension propagation (IFTP) theory…

Soft Condensed Matter · Physics 2018-02-14 Jalal Sarabadani , Bappa Ghosh , Srabanti Chaudhury , Tapio Ala-Nissila