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The sensitivity (i.e. dynamic response) of complex networked systems has not been well understood, making difficult to predict whether new macroscopic dynamic behavior will emerge even if we know exactly how individual nodes behave and how…

Systems and Control · Computer Science 2016-10-18 Marco Tulio Angulo , Gabor Lippner , Yang-Yu Liu , Albert-László Barabási

Thermostatically controlled loads (TCLs) have the potential to be a valuable resource for the Balancing Authority (BA) of the future. Examples of TCLs include household appliances such as air conditioners, water heaters, and refrigerators.…

Systems and Control · Electrical Eng. & Systems 2020-09-29 Austin R. Coffman , Ana Bušić , Prabir Barooah

Learning from data has led to paradigm shifts in a multitude of disciplines, including web, text, and image search, speech recognition, as well as bioinformatics. Can machine learning enable similar breakthroughs in understanding quantum…

The past two decades have seen a revolution in statistical physics, generalizing it to apply to systems of arbitrary size, evolving while arbitrarily far from equilibrium. Many of these new results are based on analyzing the dynamics of the…

Statistical Mechanics · Physics 2022-08-08 David H. Wolpert

A thermodynamic model of a plasma boundary layer, characterized by enhanced temperature contrasts is proposed. The theory is constructed to determine the inner boundary temperature $T_1$ for a specified outer (colder) boundary temperature…

Plasma Physics · Physics 2026-03-31 Swadesh M. Mahajan , David R. Hatch , Zensho Yoshida , Mike Kotschenreuther

Physics-informed neural networks (PINNs) offer a unified framework for solving both forward and inverse problems of differential equations, yet their performance and physical consistency strongly depend on how governing laws are…

Machine Learning · Computer Science 2026-03-31 Guojie Li , Liu Hong

When applied to binary solutions, thermal gradients lead to the generation of concentration-gradients and thus to inhomogeneous systems. While being known for more than 150 years, the molecular origins for this phenomenon are still debated,…

Soft Condensed Matter · Physics 2023-12-21 Mario Araujo-Rocha , Alejandro Diaz-Marquez , Guillaume Stirnemann

A consistent description of simultaneous heat and particle transport, including cross effects, and the associated entropy balance is given in the framework of a deterministic dynamical system. This is achieved by a multibaker map where,…

chao-dyn · Physics 2009-10-31 Laszlo Matyas , Tamas Tel , Jurgen Vollmer

Diffusion models excel at creating visually impressive images but often struggle to generate images with a specified topology. The Betti number, which represents the number of structures in an image, is a fundamental measure in topology.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Saumya Gupta , Dimitris Samaras , Chao Chen

Understanding molecular state evolution is central to many disciplines, including molecular dynamics, precision measurement, and molecule-based quantum technology. Details of the evolution are obscured when observing a statistical ensemble…

Atomic Physics · Physics 2024-08-05 Yu Liu , Julian Schmidt , Zhimin Liu , David R. Leibrandt , Dietrich Leibfried , Chin-wen Chou

The thermodynamics of a quantum system of layers containing perpendicularly oriented dipolar molecules is studied within an oscillator approximation for both bosonic and fermionic species. The system is assumed to be built from chains with…

Quantum Gases · Physics 2013-04-19 J. R. Armstrong , N. T. Zinner , D. V. Fedorov , A. S. Jensen

We prove that the transport of any differentiable scalar observable in $d$-dimensional non-equilibrium systems is bounded from above by the total entropy production scaled by the amount the observation "stretches" microscopic coordinates.…

Statistical Mechanics · Physics 2024-10-10 Cai Dieball , Aljaž Godec

We show how to construct non-equilibrium thermodynamics for systems too small to be considered thermodynamically in a traditional sense. Through the use of a non-equilibrium ensemble of many replicas of the system which can be viewed as a…

Statistical Mechanics · Physics 2007-05-23 J. M. Rubi , D. Bedeaux , S. Kjelstrup

Data collection is often difficult in critical fields such as medicine, physics, and chemistry. As a result, classification methods usually perform poorly with these small datasets, leading to weak predictive performance. Increasing the…

Machine Learning · Computer Science 2024-11-07 Andrei Margeloiu , Xiangjian Jiang , Nikola Simidjievski , Mateja Jamnik

The network of biochemical reactions inside living organisms is characterized by an overwhelming complexity which stems from the sheer number of reactions and from the complicated topology of biochemical cycles. However the high speed of…

Biological Physics · Physics 2009-10-30 Edoardo Milotti , Alessio Del Fabbro , Roberto Chignola

We investigate the role of the thermodynamic (TD) force, as an essential and sufficient technical ingredient for an efficient and accurate adaptive resolution algorithm. Such a force applied in the coupling region of an adaptive resolution…

Computational Physics · Physics 2018-07-16 Christian Krekeler , Animesh Agarwal , Christoph Junghans , Matej Praprotnik , Luigi Delle Site

We propose a fully autonomous, thermodynamically consistent set of chemical reactions that implements a spiking neuron. This chemical neuron is able to learn input patterns in a Hebbian fashion. The system is scalable to arbitrarily many…

Neural and Evolutionary Computing · Computer Science 2020-09-29 Jakub Fil , Dominique Chu

Chemical and biological networks can describe a wide variety of processes, from gene regulatory networks to biochemical oscillations. Modeled by chemical master equations, these processes are inherently stochastic, as fluctuations dominate…

Statistical Mechanics · Physics 2025-12-23 Schuyler B. Nicholson , Luis Pedro García-Pintos

We investigate the stability properties of two different classes of metabolic cycles using a combination of analytical and computational methods. Using principles from structural kinetic modeling (SKM), we show that the stability of…

Molecular Networks · Quantitative Biology 2010-07-29 Ed Reznik , Daniel Segrè

Predicting the impact of single-point amino acid mutations on protein stability is essential for understanding disease mechanisms and advancing drug development. Protein stability, quantified by changes in Gibbs free energy ($\Delta\Delta…

Machine Learning · Computer Science 2025-01-31 Karishma Thakrar , Jiangqin Ma , Max Diamond , Akash Patel