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The difference-in-differences (DiD) design is a quasi-experimental method for estimating treatment effects. In staggered DiD with multiple treatment groups and periods, estimation based on the two-way fixed effects model yields negative…

Methodology · Statistics 2026-03-05 Yuhao Deng , Le Kang

Indirect comparisons of treatment-specific outcomes across separate studies often inform decision-making in the absence of head-to-head randomized comparisons. Differences in baseline characteristics between study populations may introduce…

Applications · Statistics 2020-04-09 David Cheng , Rajeev Ayyagari , James Signorovitch

Stochastic approximation (SA) is a key method used in statistical learning. Recently, its non-asymptotic convergence analysis has been considered in many papers. However, most of the prior analyses are made under restrictive assumptions…

Machine Learning · Statistics 2019-06-18 Belhal Karimi , Blazej Miasojedow , Eric Moulines , Hoi-To Wai

Coarsened exact matching (CEM) is often promoted as a superior alternative to propensity score matching (PSM) for addressing imbalance, model dependence, bias, and efficiency. However, this recommendation remains uncertain. First, CEM is…

Methodology · Statistics 2026-02-03 Fei Wan

Simulation studies are commonly used to evaluate the performance of newly developed meta-analysis methods. For methodology that is developed for an aggregated data meta-analysis, researchers often resort to simulation of the aggregated data…

Applications · Statistics 2022-01-19 Edwin R. van den Heuvel , Osama Almalik , Zhuozhao Zhan

Unmeasured confounding is a key threat to reliable causal inference based on observational studies. Motivated from two powerful natural experiment devices, the instrumental variables and difference-in-differences, we propose a new method…

Methodology · Statistics 2021-11-09 Ting Ye , Ashkan Ertefaie , James Flory , Sean Hennessy , Dylan S. Small

Difference-in-Differences (DiD) and Synthetic Control (SC) are widely used methods for causal inference in panel data, each with distinct strengths and limitations. We propose a novel method for short-panel causal inference that integrates…

Econometrics · Economics 2025-09-26 Yixiao Sun , Haitian Xie , Yuhang Zhang

Reliable treatment effect estimation from observational data depends on the availability of all confounding information. While much work has targeted treatment effect estimation from observational data, there is relatively little work in…

Machine Learning · Statistics 2020-11-18 Shirly Wang , Seung Eun Yi , Shalmali Joshi , Marzyeh Ghassemi

For settings with a binary treatment and a binary outcome, instrumental variables can be used to construct bounds on a causal treatment effect. With continuous outcomes, meaningful bounds are more difficult to obtain because the domain of…

Methodology · Statistics 2013-03-26 Tao Liu , Joseph W. Hogan

A major challenge in estimating treatment effects in observational studies is the reliance on untestable conditions such as the assumption of no unmeasured confounding. In this work, we propose an algorithm that can falsify the assumption…

Methodology · Statistics 2025-06-03 Rickard K. A. Karlsson , Jesse H. Krijthe

Reinforcement learning control algorithms face significant challenges due to out-of-distribution and inefficient exploration problems. While model-based reinforcement learning enhances the agent's reasoning and planning capabilities by…

Machine Learning · Computer Science 2025-03-19 Sunbowen Lee , Yicheng Gong , Chao Deng

The use of machine learning systems to support decision making in healthcare raises questions as to what extent these systems may introduce or exacerbate disparities in care for historically underrepresented and mistreated groups, due to…

Machine Learning · Computer Science 2019-07-16 Stephen Pfohl , Tony Duan , Daisy Yi Ding , Nigam H. Shah

Artificial intelligence (AI)-driven decision support systems can improve diagnostic accuracy and efficiency in computational pathology. However, collaboration between human experts and AI may introduce cognitive biases such as automation…

Human-Computer Interaction · Computer Science 2026-03-16 Emely Rosbach , Jonas Ammeling , Jonathan Ganz , Christof Albert Bertram , Thomas Conrad , Andreas Riener , Marc Aubreville

Sequential Social Dilemmas (SSDs) provide a key framework for studying how cooperation emerges when individual incentives conflict with collective welfare. In Multi-Agent Reinforcement Learning, these problems are often addressed by…

Machine Learning · Computer Science 2026-02-18 Alper Demir , Hüseyin Aydın , Kale-ab Abebe Tessera , David Abel , Stefano V. Albrecht

Studies of the effects of medical interventions increasingly take place in distributed research settings using data from multiple clinical data sources including electronic health records and administrative claims. In such settings, privacy…

Methodology · Statistics 2021-01-06 Martijn J. Schuemie , Yong Chen , David Madigan , Marc A. Suchard

A highly accurate but overconfident model is ill-suited for deployment in critical applications such as healthcare and autonomous driving. The classification outcome should reflect a high uncertainty on ambiguous in-distribution samples…

Machine Learning · Computer Science 2022-10-25 Sumedha Singla , Nihal Murali , Forough Arabshahi , Sofia Triantafyllou , Kayhan Batmanghelich

Threshold policies are decision rules that assign treatments based on whether an observable characteristic exceeds a certain threshold. They are widespread across multiple domains, including welfare programs, taxation, and clinical…

Econometrics · Economics 2025-04-08 Federico Crippa

We propose the use of Agent Based Models (ABMs) inside a reinforcement learning framework in order to better understand the relationship between automated decision making tools, fairness-inspired statistical constraints, and the social…

Computers and Society · Computer Science 2019-03-25 Efrén Cruz Cortés , Debashis Ghosh

Learning generalizeable policies from visual input in the presence of visual distractions is a challenging problem in reinforcement learning. Recently, there has been renewed interest in bisimulation metrics as a tool to address this issue;…

Machine Learning · Computer Science 2022-01-31 Martin Bertran , Walter Talbott , Nitish Srivastava , Joshua Susskind

Stepped-wedge cluster randomised trials (SW-CRTs) increasingly evaluate complex interventions, yet methodological guidance for analysing composite endpoints using generalized pairwise comparisons (GPC)remains limited. This work investigates…