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Instruction tuning is a pivotal technique for aligning large language models (LLMs) with human intentions, safety constraints, and domain-specific requirements. This survey provides a comprehensive overview of the full pipeline,…

Computation and Language · Computer Science 2025-11-20 Xudong Han , Junjie Yang , Tianyang Wang , Ziqian Bi , Xinyuan Song , Junfeng Hao , Junhao Song

Instruction tuning is crucial for enabling Large Language Models (LLMs) to solve real-world tasks. Prior work has shown the effectiveness of instruction-tuning data synthesized solely from LLMs, raising a fundamental question: Do we still…

Prompting Large Language Models (LLMs), or providing context on the expected model of operation, is an effective way to steer the outputs of such models to satisfy human desiderata after they have been trained. But in rapidly evolving…

Machine Learning · Computer Science 2025-08-08 Younwoo Choi , Muhammad Adil Asif , Ziwen Han , John Willes , Rahul G. Krishnan

Instruction-tuning is a widely adopted finetuning method that enables large language models (LLMs) to generate output that more closely resembles human responses. However, no studies have shown that instruction-tuning actually teaches LLMs…

Computation and Language · Computer Science 2024-08-12 Khai Loong Aw , Syrielle Montariol , Badr AlKhamissi , Martin Schrimpf , Antoine Bosselut

Large language models (LLMs) hold the promise of solving diverse tasks when provided with appropriate natural language prompts. However, prompting often leads models to make predictions with lower accuracy compared to finetuning a model…

Computation and Language · Computer Science 2024-08-13 Chenyang Zhao , Xueying Jia , Vijay Viswanathan , Tongshuang Wu , Graham Neubig

Recent trends in Large Vision Language Models (LVLMs) research have been increasingly focusing on advancing beyond general image understanding towards more nuanced, object-level referential comprehension. In this paper, we present and delve…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Tongtian Yue , Jie Cheng , Longteng Guo , Xingyuan Dai , Zijia Zhao , Xingjian He , Gang Xiong , Yisheng Lv , Jing Liu

To acquire instruction-following capabilities, large language models (LLMs) undergo instruction tuning, where they are trained on instruction-response pairs using next-token prediction (NTP). Efforts to improve instruction tuning often…

Computation and Language · Computer Science 2026-04-21 Yuxin Xiao , Shujian Zhang , Wenxuan Zhou , Marzyeh Ghassemi , Sanqiang Zhao

Large language models (LLMs), despite their breakthroughs on many challenging benchmark tasks, lean to generate verbose responses and lack the controllability of output complexity, which is usually preferred by human users in practice. In…

Computation and Language · Computer Science 2024-06-25 Dang Nguyen , Jiuhai Chen , Tianyi Zhou

Due to limited supervised training data, large language models (LLMs) are typically pre-trained via a self-supervised "predict the next word" objective on a vast amount of unstructured text data. To make the resulting model useful to users,…

Computation and Language · Computer Science 2026-01-30 Ajay Patel , Colin Raffel , Chris Callison-Burch

Large Language Models (LLMs) for public use require continuous pre-training to remain up-to-date with the latest data. The models also need to be fine-tuned with specific instructions to maintain their ability to follow instructions…

Computation and Language · Computer Science 2024-10-15 Ishan Jindal , Chandana Badrinath , Pranjal Bharti , Lakkidi Vinay , Sachin Dev Sharma

Large Language Models (LLMs) have demonstrated significant potential in transforming clinical applications. In this study, we investigate the efficacy of four techniques in adapting LLMs for clinical use-cases: continuous pretraining,…

Existing domain-specific Large Language Models (LLMs) are typically developed by fine-tuning general-purposed LLMs with large-scale domain-specific corpora. However, training on large-scale corpora often fails to effectively organize domain…

Computation and Language · Computer Science 2025-02-11 Zhiqiang Liu , Chengtao Gan , Junjie Wang , Yichi Zhang , Zhongpu Bo , Mengshu Sun , Huajun Chen , Wen Zhang

Open-sourced large language models (LLMs) have demonstrated remarkable efficacy in various tasks with instruction tuning. However, these models can sometimes struggle with tasks that require more specialized knowledge such as translation.…

Computation and Language · Computer Science 2024-01-23 Jiali Zeng , Fandong Meng , Yongjing Yin , Jie Zhou

Large Language Models (LLMs) have shown promising results on machine translation for high resource language pairs and domains. However, in specialised domains (e.g. medical) LLMs have shown lower performance compared to standard neural…

Computation and Language · Computer Science 2025-07-31 Miguel Rios

Scientific literature understanding is crucial for extracting targeted information and garnering insights, thereby significantly advancing scientific discovery. Despite the remarkable success of Large Language Models (LLMs), they face…

Machine Learning · Computer Science 2025-04-21 Sihang Li , Jin Huang , Jiaxi Zhuang , Yaorui Shi , Xiaochen Cai , Mingjun Xu , Xiang Wang , Linfeng Zhang , Guolin Ke , Hengxing Cai

Writing radiology reports from medical images requires a high level of domain expertise. It is time-consuming even for trained radiologists and can be error-prone for inexperienced radiologists. It would be appealing to automate this task…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Yuzhe Lu , Sungmin Hong , Yash Shah , Panpan Xu

The recent advancement of large language models (LLMs) has been achieved through a combo of instruction tuning and human alignment. However, building manually crafted instruction datasets and performing human alignment become the bottleneck…

Computation and Language · Computer Science 2023-10-05 Tao Feng , Zifeng Wang , Jimeng Sun

When using supervised fine-tuning (SFT) to adapt large language models (LLMs) to specific domains, a significant challenge arises: should we use the entire SFT dataset for fine-tuning? Common practice often involves fine-tuning directly on…

Computation and Language · Computer Science 2025-05-26 Xiang Liu , Zhaoxiang Liu , Peng Wang , Kohou Wang , Huan Hu , Kai Wang , Shiguo Lian

Large vision language models (LVLMs) have demonstrated impressive performance across a wide range of tasks. These capabilities largely stem from visual instruction tuning, which fine-tunes models on datasets consisting of curated…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Myeongkyun Kang , Soopil Kim , Xiaoxiao Li , Sang Hyun Park

Following the initial flourishing of large language models (LLMs), there has been a surge in proposed large vision-language models (LVLMs) that integrate LLMs with vision capabilities. However, it has been observed that LVLMs, after tuning…

Computation and Language · Computer Science 2025-12-30 Daiki Shiono , Shumpei Miyawaki , Ryota Tanaka , Jun Suzuki
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