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Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

In-context learning (ICL), teaching a large language model (LLM) to perform a task with few-shot demonstrations rather than adjusting the model parameters, has emerged as a strong paradigm for using LLMs. While early studies primarily used…

Computation and Language · Computer Science 2023-05-24 Man Luo , Xin Xu , Zhuyun Dai , Panupong Pasupat , Mehran Kazemi , Chitta Baral , Vaiva Imbrasaite , Vincent Y Zhao

Large Language Models (LLMs) exhibit In-Context Learning (ICL), which enables the model to perform new tasks conditioning only on the examples provided in the context without updating the model's weights. While ICL offers fast adaptation…

Large Language Models (LLMs) have demonstrated exceptional performance in biochemical tasks, especially the molecule caption translation task, which aims to bridge the gap between molecules and natural language texts. However, previous…

Computation and Language · Computer Science 2025-04-08 Jiatong Li , Wei Liu , Zhihao Ding , Wenqi Fan , Yuqiang Li , Qing Li

Objectives: We aim to dynamically retrieve informative demonstrations, enhancing in-context learning in multimodal large language models (MLLMs) for disease classification. Methods: We propose a Retrieval-Augmented In-Context Learning…

Artificial Intelligence · Computer Science 2025-05-06 Zaifu Zhan , Shuang Zhou , Xiaoshan Zhou , Yongkang Xiao , Jun Wang , Jiawen Deng , He Zhu , Yu Hou , Rui Zhang

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

Computation and Language · Computer Science 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

Taking advantage of the widespread use of ontologies to organise and harmonize knowledge across several distinct domains, this paper proposes a novel approach to improve an embedding-Large Language Model (embedding-LLM) of interest by…

Computation and Language · Computer Science 2024-06-03 Francesco Ronzano , Jay Nanavati

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

With the increasing capabilities of large language models (LLMs), in-context learning (ICL) has emerged as a new paradigm for natural language processing (NLP), where LLMs make predictions based on contexts augmented with a few examples. It…

Computation and Language · Computer Science 2024-10-08 Qingxiu Dong , Lei Li , Damai Dai , Ce Zheng , Jingyuan Ma , Rui Li , Heming Xia , Jingjing Xu , Zhiyong Wu , Tianyu Liu , Baobao Chang , Xu Sun , Lei Li , Zhifang Sui

Generative Large Language Models (LLMs) are capable of being in-context learners. However, the underlying mechanism of in-context learning (ICL) is still a major research question, and experimental research results about how models exploit…

Computation and Language · Computer Science 2025-02-11 Aliakbar Nafar , Kristen Brent Venable , Parisa Kordjamshidi

Pre-trained language models (PLMs) have proven to be effective for document re-ranking task. However, they lack the ability to fully interpret the semantics of biomedical and health-care queries and often rely on simplistic patterns for…

Computation and Language · Computer Science 2023-05-09 Deepak Gupta , Dina Demner-Fushman

In-context learning (ICL) has proven to be a significant capability with the advancement of Large Language models (LLMs). By instructing LLMs using few-shot demonstrative examples, ICL enables them to perform a wide range of tasks without…

Computation and Language · Computer Science 2024-08-21 Quanyu Long , Jianda Chen , Wenya Wang , Sinno Jialin Pan

Large Language Models (LLMs) have demonstrated the ability to solve complex tasks through In-Context Learning (ICL), where models learn from a few input-output pairs without explicit fine-tuning. In this paper, we explore the capacity of…

Machine Learning · Computer Science 2024-11-26 Paimon Goulart , Evangelos E. Papalexakis

Large language models (LLMs) exhibit remarkable flexibility: they can adapt to novel tasks from in-context examples without any parameter updates, a capability known as in-context learning (ICL). Prior work on synthetic tasks has shown that…

Computation and Language · Computer Science 2026-05-29 Hua-Dong Xiong , Li Ji-An , Robert C. Wilson , Kwonjoon Lee , Xue-Xin Wei

Large language models (LLMs) have enabled a wide variety of real-world applications in various domains. However, creating a high-performing application with high accuracy remains challenging, particularly for subjective tasks like emotion…

Computation and Language · Computer Science 2025-07-01 Mengqi Wang , Tiantian Feng , Shrikanth Narayanan

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Clinical trial matching is a key process in health delivery and discovery. In practice, it is plagued by overwhelming unstructured data and unscalable manual processing. In this paper, we conduct a systematic study on scaling clinical trial…

The advancement of large language models (LLMs) has opened new frontiers in natural language processing, particularly in specialized domains like healthcare. In this paper, we propose the Incremental Curriculum-Based Fine-Tuning (ICFT)…

Computation and Language · Computer Science 2025-02-04 Robert Long , Eric Gonzalez , Harrison Fuller

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma
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