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Vascular diseases pose a significant threat to human health, with X-ray angiography established as the gold standard for diagnosis, allowing for detailed observation of blood vessels. However, angiographic X-rays expose personnel and…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Zhifeng Wang , Renjiao Yi , Xin Wen , Chenyang Zhu , Kai Xu , Kunlun He

Despite recent advances in data-independent and deep-learning algorithms, unstained live adherent cell instance segmentation remains a long-standing challenge in cell image processing. Adherent cells' inherent visual characteristics, such…

Computer Vision and Pattern Recognition · Computer Science 2023-01-30 Fei Pan , Yutong Wu , Kangning Cui , Shuxun Chen , Yanfang Li , Yaofang Liu , Adnan Shakoor , Han Zhao , Beijia Lu , Shaohua Zhi , Raymond Chan , Dong Sun

Medical image segmentation plays an important role in clinical decision making, treatment planning, and disease tracking. However, it still faces two major challenges. On the one hand, there is often a ``soft boundary'' between foreground…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Mengqi Lei , Haochen Wu , Xinhua Lv , Xin Wang

Accurate retinal vessel segmentation is a critical prerequisite for quantitative analysis of retinal images and computer-aided diagnosis of vascular diseases such as diabetic retinopathy. However, the elongated morphology, wide scale…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Ruiqi Song , Lei Liu , Ya-Nan Zhang , Chao Wang , Xiaoning Li , Nan Mu

Although the preservation of shape continuity and physiological anatomy is a natural assumption in the segmentation of medical images, it is often neglected by deep learning methods that mostly aim for the statistical modeling of input data…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Yousef Yeganeh , Azade Farshad , Goktug Guevercin , Amr Abu-zer , Rui Xiao , Yongjian Tang , Ehsan Adeli , Nassir Navab

Accurate retinal vessel (RV) segmentation is a crucial step in the quantitative assessment of retinal vasculature, which is needed for the early detection of retinal diseases and other conditions. Numerous studies have been conducted to…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Trung Dang , Huy Hoang Nguyen , Aleksei Tiulpin

In recent years, the use of deep learning is becoming increasingly popular in computer vision. However, the effective training of deep architectures usually relies on huge sets of annotated data. This is critical in the medical field where…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Paolo Andreini , Simone Bonechi , Monica Bianchini , Alessandro Mecocci , Franco Scarselli , Andrea Sodi

Retinal image segmentation plays an important role in automatic disease diagnosis. This task is very challenging because the complex structure and texture information are mixed in a retinal image, and distinguishing the information is…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Shihao Zhang , Huazhu Fu , Yanwu Xu , Yanxia Liu , Mingkui Tan

The analysis of organ vessels is essential for computer-aided diagnosis and surgical planning. But it is not a easy task since the fine-detailed connected regions of organ vessel bring a lot of ambiguity in vessel segmentation and sub-type…

Image and Video Processing · Electrical Eng. & Systems 2021-06-01 Chenxin Li , Wenao Ma , Liyan Sun , Xinghao Ding , Yue Huang , Guisheng Wang , Yizhou Yu

Pathological alterations in the human vascular system underlie many chronic diseases, such as atherosclerosis and aneurysms. However, manually analyzing diagnostic images of the vascular system, such as computed tomographic angiograms…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Alireza Bagheri Rajeoni , Breanna Pederson , Ali Firooz , Hamed Abdollahi , Andrew K. Smith , Daniel G. Clair , Susan M. Lessner , Homayoun Valafar

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging modality for the visualisation of microvasculature in vivo that has encountered broad adoption in retinal research. OCTA potential in the assessment of…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Ylenia Giarratano , Eleonora Bianchi , Calum Gray , Andrew Morris , Tom MacGillivray , Baljean Dhillon , Miguel O. Bernabeu

Many deep learning based methods have been proposed for retinal vessel segmentation, however few of them focus on the connectivity of segmented vessels, which is quite important for a practical computer-aided diagnosis system on retinal…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Rui Xu , Tiantian Liu , Xinchen Ye , Yen-Wei Chen

Experts use retinal images and vessel trees to detect and diagnose various eye, blood circulation, and brain-related diseases. However, manual segmentation of retinal images is a time-consuming process that requires high expertise and is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Alnur Alimanov , Md Baharul Islam

Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

Despite advances in data augmentation and transfer learning, convolutional neural networks (CNNs) difficultly generalise to unseen domains. When segmenting brain scans, CNNs are highly sensitive to changes in resolution and contrast: even…

Image and Video Processing · Electrical Eng. & Systems 2023-03-01 Benjamin Billot , Douglas N. Greve , Oula Puonti , Axel Thielscher , Koen Van Leemput , Bruce Fischl , Adrian V. Dalca , Juan Eugenio Iglesias

Retinal diseases remain among the leading preventable causes of visual impairment worldwide. Automated screening based on fundus image analysis has the potential to expand access to early detection, particularly in underserved populations.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Ali Akram

The performance of diagnostic Computer-Aided Design (CAD) systems for retinal diseases depends on the quality of the retinal images being screened. Thus, many studies have been developed to evaluate and assess the quality of such retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Saif Khalid , Hatem A. Rashwan , Saddam Abdulwahab , Mohamed Abdel-Nasser , Facundo Manuel Quiroga , Domenec Puig

The task of blood vessel segmentation in microscopy images is crucial for many diagnostic and research applications. However, vessels can look vastly different, depending on the transient imaging conditions, and collecting data for…

Image and Video Processing · Electrical Eng. & Systems 2019-08-19 Shir Gur , Lior Wolf , Lior Golgher , Pablo Blinder

Image segmentation is a fundamental and challenging problem in computer vision with applications spanning multiple areas, such as medical imaging, remote sensing, and autonomous vehicles. Recently, convolutional neural networks (CNNs) have…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Ali Hatamizadeh

Image processing techniques provide important assistance to physicians and relieve their workload in different tasks. In particular, identifying objects of interest such as lesions and anatomical structures from the image is a challenging…

Medical Physics · Physics 2020-05-20 Meysam Tavakoli , Mahdieh Nazar