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Machine learning, particularly graph learning, is gaining increasing recognition for its transformative impact across various fields. One such promising application is in the realm of molecule design and discovery, notably within the…

Machine Learning · Computer Science 2024-01-10 Nianzu Yang , Huaijin Wu , Kaipeng Zeng , Yang Li , Junchi Yan

AI and Machine Learning can offer powerful tools to help in the fight against Covid-19. In this paper we present a study and a concrete tool based on machine learning to predict the prognosis of hospitalised patients with Covid-19. In…

Machine Learning · Computer Science 2020-10-12 Alfonso Emilio Gerevini , Roberto Maroldi , Matteo Olivato , Luca Putelli , Ivan Serina

Quick and accurate medical diagnosis is crucial for the successful treatment of a disease. Using machine learning algorithms, we have built two models to predict a hematologic disease, based on laboratory blood test results. In one…

Machine Learning · Statistics 2020-06-09 Gregor Gunčar , Matjaž Kukar , Mateja Notar , Miran Brvar , Peter Černelč , Manca Notar , Marko Notar

Machine learning has huge potential to revolutionize the field of drug discovery and is attracting increasing attention in recent years. However, lacking domain knowledge (e.g., which tasks to work on), standard benchmarks and data…

In this manuscript we analyze a data set containing information on children with Hodgkin Lymphoma (HL) enrolled on a clinical trial. Treatments received and survival status were collected together with other covariates such as demographics…

Quantitative Methods · Quantitative Biology 2021-03-29 Cédric Beaulac , Jeffrey S. Rosenthal , Qinglin Pei , Debra Friedman , Suzanne Wolden , David Hodgson

Machine Learning is becoming a pivotal aspect of many systems today, offering newfound performance on classification and prediction tasks, but this rapid integration also comes with new unforeseen vulnerabilities. To harden these systems…

Cryptography and Security · Computer Science 2022-02-22 Ahmed Abdou , Ryan Sheatsley , Yohan Beugin , Tyler Shipp , Patrick McDaniel

Reaction prediction remains one of the major challenges for organic chemistry, and is a pre-requisite for efficient synthetic planning. It is desirable to develop algorithms that, like humans, "learn" from being exposed to examples of the…

Chemical Physics · Physics 2017-06-01 Jennifer N. Wei , David Duvenaud , Alán Aspuru-Guzik

Many multi-genic systemic diseases such as neurological disorders, inflammatory diseases, and the majority of cancers do not have effective treatments yet. Reinforcement learning powered systems pharmacology is a potentially effective…

Biomolecules · Quantitative Biology 2022-02-25 Ryan K. Tan , Yang Liu , Lei Xie

Engineering new glass compositions have experienced a sturdy tendency to move forward from (educated) trial-and-error to data- and simulation-driven strategies. In this work, we developed a computer program that combines data-driven…

Materials Science · Physics 2021-03-17 Daniel R. Cassar , Gisele G. dos Santos , Edgar D. Zanotto

Sentiment Analysis is an important algorithm in Natural Language Processing which is used to detect sentiment within some text. In our project, we had chosen to work on analyzing reviews of various drugs which have been reviewed in form of…

Computation and Language · Computer Science 2020-03-27 Sairamvinay Vijayaraghavan , Debraj Basu

This work aims to develop explainable models to predict the interactions between bitter molecules and TAS2Rs via traditional machine-learning and deep-learning methods starting from experimentally validated data. Bitterness is one of the…

Biomolecules · Quantitative Biology 2024-06-24 Francesco Ferri , Marco Cannariato , Lorenzo Pallante , Eric A. Zizzi , Marco A. Deriu

In recent years, numerous machine learning models which attempt to solve polypharmacy side effect identification, drug-drug interaction prediction and combination therapy design tasks have been proposed. Here, we present a unified…

Machine Learning · Computer Science 2021-12-14 Benedek Rozemberczki , Stephen Bonner , Andriy Nikolov , Michael Ughetto , Sebastian Nilsson , Eliseo Papa

Historically, games of all kinds have often been the subject of study in scientific works of Computer Science, including the field of machine learning. By using machine learning techniques and applying them to a game with defined rules or a…

Machine Learning · Computer Science 2018-10-10 Felipe Zilio , Marcelo Prates , Luis Lamb

Procedural content generation in video games has a long history. Existing procedural content generation methods, such as search-based, solver-based, rule-based and grammar-based methods have been applied to various content types such as…

Artificial Intelligence · Computer Science 2020-10-12 Jialin Liu , Sam Snodgrass , Ahmed Khalifa , Sebastian Risi , Georgios N. Yannakakis , Julian Togelius

One of the key challenges to predict odor from molecular structure is unarguably our limited understanding of the odor space and the complexity of the underlying structure-odor relationships. Here, we show that the predictive performance of…

Quantitative Methods · Quantitative Biology 2025-08-14 Akshay Sajan , Stijn Sluis , Reza Haydarlou , Sanne Abeln , Pasquale Lisena , Raphael Troncy , Caro Verbeek , Inger Leemans , Halima Mouhib

In recent decades, traditional drug research and development have been facing challenges such as high cost, long timelines, and high risks. To address these issues, many computational approaches have been suggested for predicting the…

Quantitative Methods · Quantitative Biology 2023-09-13 Chunyan Ao , Zhichao Xiao , Lixin Guan , Liang Yu

Prediction of toxicity levels of chemical compounds is an important issue in Quantitative Structure-Activity Relationship (QSAR) modeling. Although toxicity prediction has achieved significant progress in recent times through deep learning,…

Machine Learning · Computer Science 2019-07-22 Abdul Karim , Jaspreet Singh , Avinash Mishra , Abdollah Dehzangi , M. A. Hakim Newton , Abdul Sattar

Recent times are witnessing rapid development in machine learning algorithm systems, especially in reinforcement learning, natural language processing, computer and robot vision, image processing, speech, and emotional processing and…

This review systematizes the emerging literature for causal inference using deep neural networks under the potential outcomes framework. It provides an intuitive introduction on how deep learning can be used to estimate/predict…

Machine Learning · Computer Science 2023-11-30 Bernard Koch , Tim Sainburg , Pablo Geraldo , Song Jiang , Yizhou Sun , Jacob Gates Foster

We present a perspective on molecular machine learning (ML) in the field of chemical process engineering. Recently, molecular ML has demonstrated great potential in (i) providing highly accurate predictions for properties of pure components…

Chemical Physics · Physics 2025-09-01 Jan G. Rittig , Manuel Dahmen , Martin Grohe , Philippe Schwaller , Alexander Mitsos