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Background: Many mathematical models have now been employed across every area of systems biology. These models increasingly involve large numbers of unknown parameters, have complex structure which can result in substantial evaluation time…

Molecular Networks · Quantitative Biology 2018-01-15 Ian Vernon , Junli Liu , Michael Goldstein , James Rowe , Jen Topping , Keith Lindsey

In this paper, we consider several types of information and methods of combination associated with incomplete probabilistic systems. We discriminate between 'a priori' and evidential information. The former one is a description of the whole…

Artificial Intelligence · Computer Science 2013-03-26 Jose E. Cano , Serafin Moral , Juan F. Verdegay-Lopez

We discuss the use of empirical Bayes for data integration, in the sense of transfer learning. Our main interest is in settings where one wishes to learn structure (e.g. feature selection) and one only has access to incomplete data from…

Methodology · Statistics 2026-02-06 Paul Rognon-Vael , David Rossell

Bayesian methods are useful for statistical inference. However, real-world problems can be challenging using Bayesian methods when the data analyst has only limited prior knowledge. In this paper we consider a class of problems, called…

Methodology · Statistics 2019-11-20 Yixuan Qiu , Lingsong Zhang , Chuanhai Liu

The effect of bias on hypothesis formation is characterized for an automated data-driven projection pursuit neural network to extract and select features for binary classification of data streams. This intelligent exploratory process…

Machine Learning · Computer Science 2022-01-05 John Patterson , Chris Avery , Tyler Grear , Donald J. Jacobs

Decision tree induction systems are being used for knowledge acquisition in noisy domains. This paper develops a subjective Bayesian interpretation of the task tackled by these systems and the heuristic methods they use. It is argued that…

Artificial Intelligence · Computer Science 2013-04-11 Wray L. Buntine

The apparent dichotomy between information-processing and dynamical approaches to complexity science forces researchers to choose between two diverging sets of tools and explanations, creating conflict and often hindering scientific…

Neurons and Cognition · Quantitative Biology 2022-01-26 Pedro A. M. Mediano , Fernando E. Rosas , Juan Carlos Farah , Murray Shanahan , Daniel Bor , Adam B. Barrett

Bayesian Networks (BNs) are an important tool for assisting probabilistic reasoning, but despite being considered transparent models, people have trouble understanding them. Further, current User Interfaces (UIs) still do not clarify the…

Artificial Intelligence · Computer Science 2025-11-24 Erik P. Nyberg , Steven Mascaro , Ingrid Zukerman , Michael Wybrow , Duc-Minh Vo , Ann Nicholson

It has been shown that one can accommodate data (Bayes) and constraints (MaxEnt) in one method, the method of Maximum (relative) Entropy (ME) (Giffin 2007). In this paper we show a complex agent based example of inference with two different…

Methodology · Statistics 2016-09-08 Adom Giffin

Mathematical models are indispensable to the system biology toolkit for studying the structure and behavior of intracellular signaling networks. A common approach to modeling is to develop a system of equations that encode the known biology…

Quantitative Methods · Quantitative Biology 2024-06-18 Nathaniel Linden-Santangeli , Jin Zhang , Boris Kramer , Padmini Rangamani

A wide range of machine learning algorithms iteratively add data to the training sample. Examples include semi-supervised learning, active learning, multi-armed bandits, and Bayesian optimization. We embed this kind of data addition into…

Machine Learning · Statistics 2024-06-25 Julian Rodemann

In ecology we may find scenarios where the same phenomenon (species occurrence, species abundance, etc.) is observed using two different types of samplers. For instance, species data can be collected from scientific sampling with a…

Conformal prediction has emerged as a cutting-edge methodology in statistics and machine learning, providing prediction intervals with finite-sample frequentist coverage guarantees. Yet, its interplay with Bayesian statistics, often…

Methodology · Statistics 2026-03-27 Nina Deliu , Brunero Liseo

In statistics, there are a variety of methods for performing model selection that all stem from slightly different paradigms of statistical inference. The reasons for choosing one particular method over another seem to be based entirely on…

Statistics Theory · Mathematics 2019-01-29 Danica M. Ommen , Christopher P. Saunders

We propose a model-based lifelong reinforcement-learning approach that estimates a hierarchical Bayesian posterior distilling the common structure shared across different tasks. The learned posterior combined with a sample-based Bayesian…

Machine Learning · Computer Science 2022-10-24 Haotian Fu , Shangqun Yu , Michael Littman , George Konidaris

We present a framework for bridging the gap between sensor attack detection and recovery in cyber-physical systems. The proposed framework models modern-day, complex perception pipelines as bipartite graphs, which combined with anomaly…

Machine Learning · Computer Science 2026-04-14 Axel Andersson , György Dán

We introduce semiparametric Bayesian networks that combine parametric and nonparametric conditional probability distributions. Their aim is to incorporate the advantages of both components: the bounded complexity of parametric models and…

Machine Learning · Computer Science 2021-09-08 David Atienza , Concha Bielza , Pedro Larrañaga

Active inference is a state-of-the-art framework in neuroscience that offers a unified theory of brain function. It is also proposed as a framework for planning in AI. Unfortunately, the complex mathematics required to create new models --…

Machine Learning · Computer Science 2021-05-11 Théophile Champion , Marek Grześ , Howard Bowman

Empirical Bayes is a versatile approach to `learn from a lot' in two ways: first, from a large number of variables and second, from a potentially large amount of prior information, e.g. stored in public repositories. We review applications…

Methodology · Statistics 2018-03-19 Mark A. van de Wiel , Dennis E. te Beest , Magnus Münch

Ecological Momentary Assessments (EMA) capture real-time thoughts and behaviors in natural settings, producing rich longitudinal data for statistical and physiological analyses. However, the robustness of these analyses can be compromised…

Methodology · Statistics 2023-11-21 Yiheng Wei , Donald Hedeker