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Cryo-electron microscopy is a revolutionary technique that can provide 3D density maps at near-atomic resolution. However, map validation is still an open issue in the field. Despite several efforts from the community, it is possible to…

Biological Physics · Physics 2019-08-06 Sebastian Ortiz , Luka Stanisic , Boris A Rodriguez , Markus Rampp , Gerhard Hummer , Pilar Cossio

The work seeks to develop an algorithm for image reconstruction by directly inverting the non-linear data model in spectral CT. Using the non-linear data model, we formulate the image-reconstruction problem as a non-convex optimization…

Medical Physics · Physics 2021-02-23 Buxin Chen , Zheng Zhang , Dan Xia , Emil Y. Sidky , Xiaochuan Pan

Model-based methods are widely used for reconstruction in compressed sensing (CS) magnetic resonance imaging (MRI), using regularizers to describe the images of interest. The reconstruction process is equivalent to solving a composite…

Optimization and Control · Mathematics 2024-02-27 Tao Hong , Luis Hernandez-Garcia , Jeffrey A. Fessler

Most existing animal pose and shape estimation approaches reconstruct animal meshes with a parametric SMAL model. This is because the low-dimensional pose and shape parameters of the SMAL model makes it easier for deep networks to learn the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-17 Chen Li , Gim Hee Lee

This paper concerns a class of composite image reconstruction models for impluse noise removal, which is rather general and covers existing convex and nonconvex models proposed for reconstructing images with impluse noise. For this…

Optimization and Control · Mathematics 2024-03-27 Bujin Li , Shaohua Pan , Tieyong Zeng

As a critical modality for structural biology, cryogenic electron microscopy (cryo-EM) facilitates the determination of macromolecular structures at near-atomic resolution. The core computational task in single-particle cryo-EM is to…

Image and Video Processing · Electrical Eng. & Systems 2026-05-04 Suyi Chen , Haibin Ling

Multiple approaches to use deep learning for image restoration have recently been proposed. Training such approaches requires well registered pairs of high and low quality images. While this is easily achievable for many imaging modalities,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Tim-Oliver Buchholz , Mareike Jordan , Gaia Pigino , Florian Jug

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

Purpose: To evaluate a proposed method to reconstruct CT numbers that accurately mimic conventional CT numbers from spectral CT data, as would have been produced by a conventional system without effects of beam hardening. Approach: We…

Medical Physics · Physics 2022-08-10 Fredrik Grönberg , Hans Bornefalk

Sparse-view computed tomography (CT) has been adopted as an important technique for speeding up data acquisition and decreasing radiation dose. However, due to the lack of sufficient projection data, the reconstructed CT images often…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Hong Wang , Minghao Zhou , Dong Wei , Yuexiang Li , Yefeng Zheng

Recently it has been shown that precise dose control and an increase in the overall acquisition speed of atomic resolution scanning transmission electron microscope (STEM) images can be achieved by acquiring only a small fraction of the…

We present a new algorithm, called Multiresolution Regularized Expectation Maximization (MREM), for the reconstruction of gamma-ray intensity maps from COMPTEL data. The algorithm is based on the iterative Richardson-Lucy scheme to which we…

Positron emission tomography (PET) is widely used for clinical diagnosis. As PET suffers from low resolution and high noise, numerous efforts try to incorporate anatomical priors into PET image reconstruction, especially with the…

Medical Physics · Physics 2019-12-17 Nuobei Xie , Kuang Gong , Ning Guo , Zhixin Qin , Zhifang Wu , Huafeng Liu , Quanzheng Li

In the paper, we introduce an unconstrained analysis model based on the $\ell_{1}-\alpha \ell_{2}$ $(0< \alpha \leq1)$ minimization for the signal and image reconstruction. We develop some new technology lemmas for tight frame, and the…

Information Theory · Computer Science 2021-12-30 Peng Li , Huanmin Ge , Pengbo Geng

PET suffers from a low signal-to-noise ratio. Meanwhile, the k-space data acquisition process in MRI is time-consuming by PET-MRI systems. We aim to accelerate MRI and improve PET image quality. This paper proposed a novel joint…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Taofeng Xie , Zhuoxu Cui , Congcong Liu , Chen Luo , Huayu Wang , Yuanzhi Zhang , Xuemei Wang , Yihang Zhou , Qiyu Jin , Guoqing Chen , Dong Liang , Haifeng Wang

We study a machine learning (ML) technique for refining images acquired during in situ observation using liquid-cell transmission electron microscopy (LC-TEM). Our model is constructed using a U-Net architecture and a ResNet encoder. For…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Hiroyasu Katsuno , Yuki Kimura , Tomoya Yamazaki , Ichigaku Takigawa

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Yiran Sun , Osama Mawlawi

This study aims to improve photon counting CT (PCCT) image resolution using denoising diffusion probabilistic models (DDPM). Although DDPMs have shown superior performance when applied to various computer vision tasks, their effectiveness…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Chuang Niu , Christopher Wiedeman , Mengzhou Li , Jonathan S Maltz , Ge Wang

Long axial field-of-view PET scanners offer increased field-of-view and sensitivity compared to traditional PET scanners. However, a significant cost is associated with the densely packed photodetectors required for the extended-coverage…

Image and Video Processing · Electrical Eng. & Systems 2025-11-12 Klara Leffler , Luigi Tommaso Luppino , Samuel Kuttner , Karin Söderkvist , Jan Axelsson

Scanning Electron Microscopy (SEM) is pivotal in revealing intricate micro- and nanoscale features across various research fields. However, obtaining high-resolution SEM images presents challenges, including prolonged scanning durations and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Tom Reclik , Setareh Medghalchi , Philipp Schumacher , Maximilian Wollenweber , Talal Al-Samman , Sandra Korte-Kerzel , Ulrich Kerzel