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We propose a general strategy for autonomous guidance and insertion of a needle into a retinal blood vessel. The main challenges underpinning this task are the accurate placement of the needle-tip on the target vein and a careful needle…

Robotics · Computer Science 2023-06-21 Ji Woong Kim , Peiyao Zhang , Peter Gehlbach , Iulian Iordachita , Marin Kobilarov

Retinal vein cannulation (RVC) is a minimally invasive microsurgical procedure for treating retinal vein occlusion (RVO), a leading cause of vision impairment. However, the small size and fragility of retinal veins, coupled with the need…

Robotics · Computer Science 2025-07-30 Yi Wang , Peiyao Zhang , Mojtaba Esfandiari , Peter Gehlbach , Iulian I. Iordachita

A potential Retinal Vein Occlusion (RVO) treatment involves Retinal Vein Cannulation (RVC), which requires the surgeon to insert a microneedle into the affected retinal vein and administer a clot-dissolving drug. This procedure presents…

Robotics · Computer Science 2024-12-18 Peiyao Zhang , Peter Gehlbach , Marin Kobilarov , Iulian Iordachita

Important challenges in retinal microsurgery include prolonged operating time, inadequate force feedback, and poor depth perception due to a constrained top-down view of the surgery. The introduction of robot-assisted technology could…

Robotics · Computer Science 2023-12-08 Peiyao Zhang , Ji Woong Kim , Peter Gehlbach , Iulian Iordachita , Marin Kobilarov

Purpose: Central venous catheterization (CVC) is a critical medical procedure for vascular access, hemodynamic monitoring, and life-saving interventions. Its success remains challenging due to the need for continuous ultrasound-guided…

A fundamental challenge in retinal surgery is safely navigating a surgical tool to a desired goal position on the retinal surface while avoiding damage to surrounding tissues, a procedure that typically requires tens-of-microns accuracy. In…

During retinal microsurgery, precise manipulation of the delicate retinal tissue is required for positive surgical outcome. However, accurate manipulation and navigation of surgical tools remain difficult due to a constrained workspace and…

Robotics · Computer Science 2020-11-17 Ji Woong Kim , Peiyao Zhang , Peter Gehlbach , Iulian Iordachita , Marin Kobilarov

Subretinal injection is a critical procedure for delivering therapeutic agents to treat retinal diseases such as age-related macular degeneration (AMD). However, retinal motion caused by physiological factors such as respiration and…

Recent advancements in retinal surgery have paved the way for a modern operating room equipped with a surgical robot, a microscope, and intraoperative optical coherence tomography (iOCT)- a depth sensor widely used in retinal surgery.…

Ultrasound (US)-guided needle insertion is a critical yet challenging procedure due to dynamic imaging conditions and difficulties in needle visualization. Many methods have been proposed for automated needle insertion, but they often rely…

Robotics · Computer Science 2026-04-23 Yuelin Zhang , Qingpeng Ding , Longxiang Tang , Chengyu Fang , Shing Shin Cheng

The use of needles to access sites within organs is fundamental to many interventional medical procedures both for diagnosis and treatment. Safe and accurate navigation of a needle through living tissue to an intra-tissue target is…

In this paper, we present a robotic device for mouse tail vein injection. We propose a mouse holding mechanism to realize vein injection without anesthetizing the mouse, which consists of a tourniquet, vacuum port, and adaptive tail-end…

Robotic platforms provide consistent and precise tool positioning that significantly enhances retinal microsurgery. Integrating such systems with intraoperative optical coherence tomography (iOCT) enables image-guided robotic interventions,…

Billions of vascular access procedures are performed annually worldwide, serving as a crucial first step in various clinical diagnostic and therapeutic procedures. For pediatric or elderly individuals, whose vessels are small in size…

Robotics · Computer Science 2025-04-09 Shuaiqi Jing , Tianliang Yao , Ke Zhang , Di Wu , Qiulin Wang , Zixi Chen , Ke Chen , Peng Qi

In the last decade, various robotic platforms have been introduced that could support delicate retinal surgeries. Concurrently, to provide semantic understanding of the surgical area, recent advances have enabled microscope-integrated…

In the modern medical care, venipuncture is an indispensable procedure for both diagnosis and treatment. In this paper, unlike existing solutions that fully or partially rely on professional assistance, we propose VeniBot -- a compact…

Image and Video Processing · Electrical Eng. & Systems 2021-05-28 Yu Chen , Yuxuan Wang , Bolin Lai , Zijie Chen , Xu Cao , Nanyang Ye , Zhongyuan Ren , Junbo Zhao , Xiao-Yun Zhou , Peng Qi

From diagnosing neovascular diseases to detecting white matter lesions, accurate tiny vessel segmentation in fundus images is critical. Promising results for accurate vessel segmentation have been known. However, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Suraj Mishra , Danny Z. Chen , X. Sharon Hu

Computed Tomography (CT) image guidance enables accurate and safe minimally invasive treatment of diseases, including cancer and chronic pain, with needle-like tools via a percutaneous approach. The physician incrementally inserts and…

Automatic segmentation of retinal blood vessels from fundus images plays an important role in the computer aided diagnosis of retinal diseases. The task of blood vessel segmentation is challenging due to the extreme variations in morphology…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Avijit Dasgupta , Sonam Singh

Exudative (wet) age-related macular degeneration (AMD) is a leading cause of vision loss in older adults, typically treated with intravitreal injections. Emerging therapies, such as subretinal injections of stem cells, gene therapy, small…

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