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The increasing use of microfluidics in industrial, biomedical, and clinical applications requires a more and more precise control of the microfluidic flows and suspended particles or cells. This leads to higher demands in three-dimensional…

Fluid Dynamics · Physics 2020-11-10 Massimiliano Rossi , Rune Barnkob

Photomultiplier tubes (PMTs) are widely used in particle and nuclear physics experiments. The reconstruction of PMT waveforms is a fundamental task in these experiments, where accurate extraction of photoelectron (PE) multiplicities and…

High Energy Physics - Experiment · Physics 2026-05-29 Yiming Xu , Youwen Fan , Siyu Chen , Hongyue Duyang , Teng Li , Yaoguang Wang

Large-area PhotoMultiplier Tubes (PMT) allow to efficiently instrument Liquid Scintillator (LS) neutrino detectors, where large target masses are pivotal to compensate for neutrinos' extremely elusive nature. Depending on the detector light…

Positron emission tomography (PET) imaging is widely used in a number of clinical applications, including cancer and Alzheimer's disease (AD) diagnosis, monitoring of disease development, and treatment effect evaluation. Statistical…

Tissues and Organs · Quantitative Biology 2025-11-07 Akhil Ambekar , Robert Zielinski , Ani Eloyan

In the framework of detector development, Monte Carlo simulations play a key role in the evaluation of the expected performance and the full understanding of the behavior in beam conditions. In particular, a software which simulates the…

Instrumentation and Detectors · Physics 2019-08-21 Lia Lavezzi

PET is a functional imaging method that visualizes metabolic processes. TOF information can be derived from coincident detector signals and incorporated into image reconstruction to enhance the SNR. PET detectors are typically assessed by…

Instrumentation and Detectors · Physics 2025-04-24 Stephan Naunheim , Luis Lopes de Paiva , Vanessa Nadig , Yannick Kuhl , Stefan Gundacker , Florian Mueller , Volkmar Schulz

The large time and length scales and, not least, the vast number of particles involved in industrial-scale simulations inflate the computational costs of the Discrete Element Method (DEM) excessively. Coarse grain models can help to lower…

Computational Physics · Physics 2017-05-11 Daniel Queteschiner , Thomas Lichtenegger , Simon Schneiderbauer , Stefan Pirker

We are designing an all-scintillator Compton gamma imager for use in security investigations and remediation actions involving radioactive threat material. To satisfy requirements for a rugged and portable instrument, we have chosen solid…

Instrumentation and Detectors · Physics 2009-06-28 L. E. Sinclair , D. S. Hanna , A. M. L. MacLeod , P. R. B. Saull

Prompt Gamma Timing (PGT) is a promising technique for in vivo range verification in particle therapy, exploiting the time-of-flight between primary particles and prompt gamma rays emitted by nuclear interactions. PGT distribution is highly…

Symplectic tracking is important in accelerator beam dynamics simulation. So far, to the best of our knowledge, there is no self-consistent symplectic space-charge tracking model available in the accelerator community. In this paper, we…

Accelerator Physics · Physics 2017-02-01 Ji Qiang

Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Shaoyan Pan , Elham Abouei , Junbo Peng , Joshua Qian , Jacob F Wynne , Tonghe Wang , Chih-Wei Chang , Justin Roper , Jonathon A Nye , Hui Mao , Xiaofeng Yang

This paper provides a detailed description of a vertex fitting algorithm designed for precision measurements in low-energy particle physics experiments. An accurate reconstruction of low-momentum trajectories is facilitated by reducing the…

Instrumentation and Detectors · Physics 2024-04-30 Andrea Loreti

Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with DECT leveraging advanced X-ray source and/or detector…

Medical Physics · Physics 2024-08-28 Qiaoxin Li , Ruifeng Chen , Peng Wang , Guotao Quan , Yanfeng Du , Dong Liang , Yinsheng Li

The determination of relative stopping power (RSP) via proton computed tomography (pCT) of a patient is dependent in part on the knowledge of the incoming proton kinetic energies; the uncertainty in these energies is in turn determined by…

Photomultiplier tubes (PMTs) are widely employed in particle and nuclear physics experiments. The accuracy of PMT waveform reconstruction directly impacts the detector's spatial and energy resolution. A key challenge arises when multiple…

High Energy Physics - Experiment · Physics 2026-02-06 Kainan Liu , Jingyu Huang , Guihong Huang , Jianyi Luo

We evaluate the performance of an Omnivision OV5647 CMOS image sensor (5 Mp) for detecting radiation from Sr90 and Cs137 sources. Our experimental setup uses a Raspberry Pi 3 mini-computer for data acquisition, with image processing using…

High Energy Physics - Experiment · Physics 2025-06-18 M. Bonnett Del Alamo , R. Helaconde , C. Soncco , J. Bazo , A. M. Gago

SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…

Medical Physics · Physics 2015-06-16 Xiaolin Zhou , Minkai Yun , Xuexiang Cao , Shuangquan Liu , Lu Wang , Xianchao Huang , Long Wei

Micro pattern gaseous detectors have been widely used in position measurements of particle detection in the last two decades. In this work a novel method of track identification and reconstruction was developed for fast neutron detection by…

Instrumentation and Detectors · Physics 2015-12-16 Yi Zhang , Huiyin Wu , Shengying Zhao , Bitao Hu

We discuss the use of the Discrete Element Method (DEM) to simulate the dynamics of granular systems made up of elements with nontrivial geometries. The DEM simulator is GPU accelerated and can handle elements whose shape is defined as the…

Computational Engineering, Finance, and Science · Computer Science 2023-07-10 Ruochun Zhang , Colin Vanden Heuvel , Alexander Schepelmann , Arno Rogg , Dimitrios Apostolopoulos , Samuel Chandler , Radu Serban , Dan Negrut

Score-based generative models have demonstrated highly promising results for medical image reconstruction tasks in magnetic resonance imaging or computed tomography. However, their application to Positron Emission Tomography (PET) is still…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Imraj RD Singh , Alexander Denker , Riccardo Barbano , Željko Kereta , Bangti Jin , Kris Thielemans , Peter Maass , Simon Arridge