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The performance of image segmentation models has historically been constrained by the high cost of collecting large-scale annotated data. The Segment Anything Model (SAM) alleviates this original problem through a promptable,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Miguel Espinosa , Chenhongyi Yang , Linus Ericsson , Steven McDonagh , Elliot J. Crowley

Topological data analysis (TDA) detects geometric structure in biological data. However, many TDA algorithms are memory intensive and impractical for massive datasets. Here, we introduce a statistical protocol that reduces TDA's memory…

Quantitative Methods · Quantitative Biology 2025-09-05 Andrew J. Stier , Naichen Shi , Raed Al Kontar , Chad Giusti , Marc G. Berman

Promptable foundation models, particularly Segment Anything Model (SAM), have emerged as a promising alternative to the traditional task-specific supervised learning for image segmentation. However, many evaluation studies have found that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Rachana Sathish , Rahul Venkataramani , K S Shriram , Prasad Sudhakar

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

Source-free domain adaptation (SFDA) for segmentation aims at adapting a model trained in the source domain to perform well in the target domain with only the source model and unlabeled target data. Inspired by the recent success of Segment…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Zheang Huai , Hui Tang , Yi Li , Zhuangzhuang Chen , Xiaomeng Li

The Segment Anything Model (SAM) exhibits remarkable versatility and zero-shot learning abilities, owing largely to its extensive training data (SA-1B). Recognizing SAM's dependency on manual guidance given its category-agnostic nature, we…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Xiyu Qi , Yifan Wu , Yongqiang Mao , Wenhui Zhang , Yidan Zhang

Purpose: Accurate tool segmentation is essential in computer-aided procedures. However, this task conveys challenges due to artifacts' presence and the limited training data in medical scenarios. Methods that generalize to unseen data…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Kanyifeechukwu J. Oguine , Roger D. Soberanis-Mukul , Nathan Drenkow , Mathias Unberath

The segment anything model (SAM) was released as a foundation model for image segmentation. The promptable segmentation model was trained by over 1 billion masks on 11M licensed and privacy-respecting images. The model supports zero-shot…

Due to the flexibility of prompting, foundation models have become the dominant force in the domains of natural language processing and image generation. With the recent introduction of the Segment Anything Model (SAM), the prompt-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-08-14 Yichi Zhang , Rushi Jiao

We introduce a very general approach to the analysis of signals from their noisy measurements from the perspective of Topological Data Analysis (TDA). While TDA has emerged as a powerful analytical tool for data with pronounced topological…

Signal Processing · Electrical Eng. & Systems 2025-07-29 Juan Manuel Miramont , Kin Aun Tan , Soumendu Sundar Mukherjee , Rémi Bardenet , Subhroshekhar Ghosh

The Segment Anything Model (SAM) and similar models build a family of promptable foundation models (FMs) for image and video segmentation. The object of interest is identified using prompts, such as bounding boxes or points. With these FMs…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Caroline Magg , Hoel Kervadec , Clara I. Sánchez

Due to the inherent flexibility of prompting, foundation models have emerged as the predominant force in the fields of natural language processing and computer vision. The recent introduction of the Segment Anything Model (SAM) signifies a…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Yichi Zhang , Zhenrong Shen , Rushi Jiao

Recently, the first foundation model developed specifically for image segmentation tasks was developed, termed the "Segment Anything Model" (SAM). SAM can segment objects in input imagery based on cheap input prompts, such as one (or more)…

Computer Vision and Pattern Recognition · Computer Science 2023-11-10 Simiao Ren , Francesco Luzi , Saad Lahrichi , Kaleb Kassaw , Leslie M. Collins , Kyle Bradbury , Jordan M. Malof

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

Topological Data Analysis (TDA) is an emergent field that aims to discover topological information hidden in a dataset. TDA tools have been commonly used to create filters and topological descriptors to improve Machine Learning (ML)…

Machine Learning · Computer Science 2021-02-09 Rolando Kindelan , José Frías , Mauricio Cerda , Nancy Hitschfeld

Cryo-electron microscopy (cryo-EM) remains pivotal in structural biology, yet the task of protein particle picking, integral for 3D protein structure construction, is laden with manual inefficiencies. While recent AI tools such as Topaz and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Fei He , Zhiyuan Yang , Mingyue Gao , Biplab Poudel , Newgin Sam Ebin Sam Dhas , Rajan Gyawali , Ashwin Dhakal , Jianlin Cheng , Dong Xu

Segmentation in medical imaging is a critical component for the diagnosis, monitoring, and treatment of various diseases and medical conditions. Presently, the medical segmentation landscape is dominated by numerous specialized deep…

Segmentation quality assessment (SQA) plays a critical role in the deployment of a medical image based AI system. Users need to be informed/alerted whenever an AI system generates unreliable/incorrect predictions. With the introduction of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Yizhe Zhang , Shuo Wang , Tao Zhou , Qi Dou , Danny Z. Chen

Segmentation is an essential step for remote sensing image processing. This study aims to advance the application of the Segment Anything Model (SAM), an innovative image segmentation model by Meta AI, in the field of remote sensing image…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Lucas Prado Osco , Qiusheng Wu , Eduardo Lopes de Lemos , Wesley Nunes Gonçalves , Ana Paula Marques Ramos , Jonathan Li , José Marcato Junior

Segment Anything (SAM) has recently pushed the boundaries of segmentation by demonstrating zero-shot generalization and flexible prompting after training on over one billion masks. Despite this, its mask prediction accuracy often falls…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Zezhong Fan , Xiaohan Li , Topojoy Biswas , Kaushiki Nag , Kannan Achan