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This paper deals with a model of cellular growth called "Epigenetic Tracking", whose key features are: i) distinction bewteen "normal" and "driver" cells; ii) presence in driver cells of an epigenetic memory, that holds the position of the…

Cell Behavior · Quantitative Biology 2009-05-01 Alessandro Fontana

Based on a non-equilibrium mechanism for spatial pattern formation we study how position information can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of cells in a developing…

Molecular Networks · Quantitative Biology 2009-08-26 Thimo Rohlf , Stefan Bornholdt

During developmental processes such as embryogenesis, how a group of cells fold into specific structures, is a central question in biology that defines how living organisms form. Establishing tissue-level morphology critically relies on how…

Soft Condensed Matter · Physics 2024-07-23 Haiqian Yang , Anh Q. Nguyen , Dapeng Bi , Markus J. Buehler , Ming Guo

With the rise of modern deep learning, neural networks have become an essential part of virtually every artificial intelligence system, making it difficult even to imagine different models for intelligent behavior. In contrast, nature…

Robotics · Computer Science 2025-08-26 Alican Mertan , Nick Cheney

Soil is a complex, dynamic material, with physical properties that depend on its biological content. We propose a cellular automaton model for self-organizing soil structure, where soil aggregates and serves as food for microbial species.…

Biological Physics · Physics 2025-10-10 Riz Fernando Noronha , Kim Sneppen , Kunihiko Kaneko

Various metallic structures of complex shape, resembling natural objects such as plants, mushrooms, and seashells, were produced when growing nanowires by means of pulsed current electroplating in porous membranes. These structures occur as…

Materials Science · Physics 2013-08-05 Gennady Strukov , Galina Strukova

Self-organization is the generation of order out of local interactions in non-equilibrium [1]. It is deeply connected to all fields of science from physics, chemistry to biology where functional living structures self-assemble[2] and…

Soft Condensed Matter · Physics 2018-10-24 Utsab Khadka , Viktor Holubec , Haw Yang , Frank Cichos

Evolutionary robotics has aimed to optimize robot control and morphology to produce better and more robust robots. Most previous research only addresses optimization of control, and does this only in simulation. We have developed a…

Robotics · Computer Science 2018-05-09 Tønnes F. Nygaard , Charles P. Martin , Jim Torresen , Kyrre Glette

I propose here a new concept of information based on two relevant aspects of its expression. The first related to the undeniable fact that the expression of information modifies the physical state of its receiver. The second to the…

Populations and Evolution · Quantitative Biology 2007-05-23 Antonio Leon

Mapping conformational heterogeneity of macromolecules presents a formidable challenge to X-ray crystallography and cryo-electron microscopy, which often presume its absence. This has severely limited our knowledge of the conformations…

Biological Physics · Physics 2015-05-14 P. Schwander , R. Fung , G. N. Phillips , A. Ourmazd

This paper argues that self-awareness is a learned behavior that emerges in organisms whose brains have a sufficiently integrated, complex ability for associative learning and memory. Continual sensory input of information related to the…

Neurons and Cognition · Quantitative Biology 2007-06-13 Emmanuel Tannenbaum

As a result of a hundred million years of evolution, living animals have adapted extremely well to their ecological niche. Such adaptation implies species-specific interactions with their immediate environment by processing sensory cues and…

Disordered Systems and Neural Networks · Physics 2022-04-28 Tom Birkoben , Hermann Kohlstedt

In this article, I advance the idea that physics plays a central role in cell differentiation and makes fundamental contributions to morphogenesis, revealing the totipotent nature of the zygote. Totipotency is a persistent mechanical memory…

Biological Physics · Physics 2026-03-20 Jaime Cofre

We study the self-assembly of colloidal microgel particles at a quasi-two-dimensional air-water interface of a drying droplet. Using bright-field microscopy, we demonstrate that increasing particle elasticity drives interfacial organization…

Soft Condensed Matter · Physics 2026-03-10 Vaibhav Raj Singh Parmar , Sayantan Chanda , Rituparno Mandal , Ranjini Bandyopadhyay

Abstract: Bionic learning with fused sensing, memory and processing functions outperforms artificial neural networks running on silicon chips in terms of efficiency and footprint. However, digital hardware implementation of bionic learning…

Emerging Technologies · Computer Science 2022-02-22 Shijie Wang , Xi Chen , Chao Zhao , Yuxin Kong , Baojun Lin , Yongyi Wu , Zhaozhao Bi , Ziyi Xuan , Tao Li , Yuxiang Li , Wei Zhang , En Ma , Zhongrui Wang , Wei Ma

The mechanism by which cells measure the dimension of the organ in which they are embedded, and slow down their growth when the final size is reached, is a long-standing problem of developmental biology. The role of mechanics in this…

Biological Physics · Physics 2023-07-19 Alexander Erlich , Pierre Recho

Beyond conventional organic thin-film transistors, this thesis explores possible paths for the fourth wave of organic electronics. In this context, mixed ionic-electronic conductors and organic electro-chemical transistors (OECTs) are…

Emerging Technologies · Computer Science 2021-11-19 Hans Kleemann

Molecular electronics and other technologies whose components comprise individual molecules have been pursued for half a century because the molecular scale represents the limit of miniaturisation of objects whose structure is tuneable for…

Artificial Intelligence (AI) and Machine Learning (ML) are weaving their way into the fabric of society, where they are playing a crucial role in numerous facets of our lives. As we witness the increased deployment of AI and ML in various…

Emerging Technologies · Computer Science 2022-12-23 Sasitharan Balasubramaniam , Samitha Somathilaka , Sehee Sun , Adrian Ratwatte , Massimiliano Pierobon

Soft electronics are a promising and revolutionary alternative for traditional electronics when safe physical interaction between machines and the human body is required. Among various materials architectures developed for producing soft…

Applied Physics · Physics 2021-04-16 Kaveh Alizadeh