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Deep learning models have shown promising performance for cell nucleus segmentation in the field of pathology image analysis. However, training a robust model from multiple domains remains a great challenge for cell nucleus segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Dawei Fan , Yifan Gao , Jiaming Yu , Yanping Chen , Wencheng Li , Chuancong Lin , Kaibin Li , Changcai Yang , Riqing Chen , Lifang Wei

Blood cell classification and counting are vital for the diagnosis of various blood-related diseases, such as anemia, leukemia, and thrombocytopenia. The manual process of blood cell classification and counting is time-consuming, prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Sohag Kumar Mondal , Md. Simul Hasan Talukder , Mohammad Aljaidi , Rejwan Bin Sulaiman , Md Mohiuddin Sarker Tushar , Amjad A Alsuwaylimi

Generally, microscopy image analysis in biology relies on the segmentation of individual nuclei, using a dedicated stained image, to identify individual cells. However stained nuclei have drawbacks like the need for sample preparation, and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Gendarme Mathieu , Lambert Annika M. , El Debs Bachir

Unsupervised cell type identification is crucial for uncovering and characterizing heterogeneous populations in single cell omics studies. Although a range of clustering methods have been developed, most focus exclusively on intrinsic…

Artificial Intelligence · Computer Science 2025-12-12 Liang Peng , Haopeng Liu , Yixuan Ye , Cheng Liu , Wenjun Shen , Si Wu , Hau-San Wong

Deep learning models have revolutionized the field of medical image analysis, due to their outstanding performances. However, they are sensitive to spurious correlations, often taking advantage of dataset bias to improve results for…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Diogo J. Araújo , M. Rita Verdelho , Alceu Bissoto , Jacinto C. Nascimento , Carlos Santiago , Catarina Barata

Counterfactual causal inference faces significant challenges when extended to multi-category, multi-valued treatments, where complex cross-effects between heterogeneous interventions are difficult to model. Existing methodologies remain…

Machine Learning · Computer Science 2025-11-04 Xiaopeng Ke , Yihan Yu , Ruyue Zhang , Zhishuo Zhou , Fangzhou Shi , Chang Men , Zhengdan Zhu

Whole brain segmentation using deep learning (DL) is a very challenging task since the number of anatomical labels is very high compared to the number of available training images. To address this problem, previous DL methods proposed to…

Image and Video Processing · Electrical Eng. & Systems 2019-06-06 Pierrick Coupé , Boris Mansencal , Michaël Clément , Rémi Giraud , Baudouin Denis de Senneville , Vinh-Thong Ta , Vincent Lepetit , José V. Manjon

Semi-supervised techniques have removed the barriers of large scale labelled set by exploiting unlabelled data to improve the performance of a model. In this paper, we propose a semi-supervised deep multi-task classification and…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 R. M. Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot

The spread of deepfakes poses significant security concerns, demanding reliable detection methods. However, diverse generation techniques and class imbalance in datasets create challenges. We propose CAE-Net, a Convolution- and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Anindya Bhattacharjee , Kaidul Islam , Kafi Anan , Ashir Intesher , Abrar Assaeem Fuad , Utsab Saha , Hafiz Imtiaz

In this paper, we study the problem of learning image classification models with label noise. Existing approaches depending on human supervision are generally not scalable as manually identifying correct or incorrect labels is…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Kuang-Huei Lee , Xiaodong He , Lei Zhang , Linjun Yang

Due to morphological similarity at the microscopic level, making an accurate and time-sensitive distinction between blood cells affected by Acute Lymphocytic Leukemia (ALL) and their healthy counterparts calls for the usage of machine…

Computer Vision and Pattern Recognition · Computer Science 2022-07-29 Sai Mattapalli , Rishi Athavale

Automatic cell segmentation is an essential step in the pipeline of computer-aided diagnosis (CAD), such as the detection and grading of breast cancer. Accurate segmentation of cells can not only assist the pathologists to make a more…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Muyi Sun , Zeyi Yao , Guanhong Zhang

In the field of medical imaging, the advent of deep learning, especially the application of convolutional neural networks (CNNs) has revolutionized the analysis and interpretation of medical images. Nevertheless, deep learning methods…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Xin Li , Wenhui Zhu , Peijie Qiu , Oana M. Dumitrascu , Amal Youssef , Yalin Wang

We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach

Lane detection plays a crucial role in autonomous driving by providing vital data to ensure safe navigation. Modern algorithms rely on anchor-based detectors, which are then followed by a label-assignment process to categorize training…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Sapir Kontente , Roy Orfaig , Ben-Zion Bobrovsky

The precise subtype classification of myeloproliferative neoplasms (MPNs) based on multimodal information, which assists clinicians in diagnosis and long-term treatment plans, is of great clinical significance. However, it remains a great…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Yuan Zhang , Yaolei Qi , Xiaoming Qi , Yongyue Wei , Guanyu Yang

Fluorescence Lifetime Imaging (FLI) is a critical molecular imaging modality that provides unique information about the tissue microenvironment, which is invaluable for biomedical applications. FLI operates by acquiring and analyzing photon…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Ismail Erbas , Vikas Pandey , Navid Ibtehaj Nizam , Nanxue Yuan , Amit Verma , Margarida Barosso , Xavier Intes

Medical image segmentation, particularly in multi-domain scenarios, requires precise preservation of anatomical structures across diverse representations. While deep learning has advanced this field, existing models often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Afshin Bozorgpour , Sina Ghorbani Kolahi , Reza Azad , Ilker Hacihaliloglu , Dorit Merhof

Batch effects represent a major confounder in genomic diagnostics. In copy number variant (CNV) detection from NGS, many algorithms compare read depth between test samples and a reference sample, assuming they are process-matched. When this…

Genomics · Quantitative Biology 2026-01-16 Austin Talbot , Yue Ke

Some real-world domains, such as Agriculture and Healthcare, comprise early-stage disease indications whose recording constitutes a rare event, and yet, whose precise detection at that stage is critical. In this type of highly imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Veysel Kocaman , Ofer M. Shir , Thomas Bäck