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The use of neural networks to directly predict three-dimensional dose distributions for automatic planning is becoming popular. However, the existing methods only use patient anatomy as input and assume consistent beam configuration for all…

The next great leap toward improving treatment of cancer with radiation will require the combined use of online adaptive and magnetic resonance guided radiation therapy techniques with automatic X-ray beam orientation selection.…

Medical Physics · Physics 2019-08-14 Ryan Neph , Yangsibo Huang , Youming Yang , Ke Sheng

We propose the BayesDose-Framework, a Bayesian approach for fast and accurate dose prediction in proton therapy. Our framework is based on a previously published deterministic LSTM model and is trained and evaluated on simulated beamlet…

Medical Physics · Physics 2023-07-04 Luke Voss , Ahmad Neishabouri , Tim Ortkamp , Andrea Mairani , Niklas Wahl

We demonstrate the application of mixture density networks (MDNs) in the context of automated radiation therapy treatment planning. It is shown that an MDN can produce good predictions of dose distributions as well as reflect uncertain…

Medical Physics · Physics 2021-07-06 Viktor Nilsson , Hanna Gruselius , Tianfang Zhang , Geert De Kerf , Michaël Claessens

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

Near infrared diffuse optical tomography (DOT) provides an imaging modality for the oxygenation of tissue. In this paper, we propose a novel machine learning algorithm based on time-domain radiative transfer equation. We use temporal…

Medical Physics · Physics 2020-11-26 Yu-ichi Takamizu , Masayuki Umemura , Hidenobu Yajima , Makito Abe , Yoko Hoshi

Predicting counterfactual distributions in complex dynamical systems is essential for scientific modeling and decision-making in domains such as public health and medicine. However, existing methods often rely on point estimates or purely…

Machine Learning · Computer Science 2025-09-15 Wenhao Mu , Zhi Cao , Mehmed Uludag , Alexander Rodríguez

Radio-frequency dosimetry is an important process in human safety and for compliance of related products. Recently, computational human models generated from medical images have often been used for such assessment, especially to consider…

Machine Learning · Computer Science 2020-04-29 Essam A. Rashed , Yinliang Diao , Akimasa Hirata

Diffusion models have recently achieved great success in the synthesis of high-quality images and videos. However, the existing denoising techniques in diffusion models are commonly based on step-by-step noise predictions, which suffers…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Hancheng Ye , Jiakang Yuan , Renqiu Xia , Xiangchao Yan , Tao Chen , Junchi Yan , Botian Shi , Bo Zhang

Accurately translating medical images between different modalities, such as Computed Tomography (CT) to Magnetic Resonance Imaging (MRI), has numerous downstream clinical and machine learning applications. While several methods have been…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Yuwen Chen , Nicholas Konz , Hanxue Gu , Haoyu Dong , Yaqian Chen , Lin Li , Jisoo Lee , Maciej A. Mazurowski

Score-based diffusion models have shown significant promise in the field of sparse-view CT reconstruction. However, the projection dataset is large and riddled with redundancy. Consequently, applying the diffusion model to unprocessed data…

Image and Video Processing · Electrical Eng. & Systems 2025-05-16 Pengfei Yu , Bin Huang , Minghui Zhang , Weiwen Wu , Shaoyu Wang , Qiegen Liu

Accurate brain tumor diagnosis relies on the assessment of multiple Magnetic Resonance Imaging (MRI) sequences. However, in clinical practice, the acquisition of certain sequences may be affected by factors like motion artifacts or contrast…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Moinak Bhattacharya , Saumya Gupta , Annie Singh , Chao Chen , Gagandeep Singh , Prateek Prasanna

In recent years, Denoising Diffusion Models have demonstrated remarkable success in generating semantically valuable pixel-wise representations for image generative modeling. In this study, we propose a novel end-to-end framework, called…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Zhaohu Xing , Liang Wan , Huazhu Fu , Guang Yang , Lei Zhu

High-precision controllable remote sensing image generation is both meaningful and challenging. Existing diffusion models often produce low-fidelity images due to their inability to adequately capture morphological details, which may affect…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Ziqi Ye , Shuran Ma , Jie Yang , Xiaoyi Yang , Yi Yang , Ziyang Gong , Xue Yang , Haipeng Wang

The Diffusion Probabilistic Model (DPM) has demonstrated remarkable performance across a variety of generative tasks. The inherent randomness in diffusion models helps address issues such as blurring at the edges of medical images and…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Yilong Hu , Shijie Chang , Lihe Zhang , Feng Tian , Weibing Sun , Huchuan Lu

Diffusion model (DM) has achieved SOTA performance by modeling the image synthesis process into a sequential application of a denoising network. However, different from image synthesis, image restoration (IR) has a strong constraint to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-17 Bin Xia , Yulun Zhang , Shiyin Wang , Yitong Wang , Xinglong Wu , Yapeng Tian , Wenming Yang , Luc Van Gool

With the great success of diffusion models (DMs) in generating realistic synthetic vision data, many researchers have investigated their potential in decision-making and control. Most of these works utilized DMs to sample directly from the…

Machine Learning · Computer Science 2026-05-19 Hanye Zhao , Xiaoshen Han , Zhengbang Zhu , Minghuan Liu , Yong Yu , De-Chuan Zhan , Weinan Zhang

Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…

Medical Physics · Physics 2023-12-05 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Modeling the absorbed dose during X-ray imaging is essential for optimizing radiation exposure. Monte Carlo simulations (MCS) are the gold standard for precise 3D dose estimation but require significant computation time. Deep learning…

Medical Physics · Physics 2025-02-14 Maxime Rousselot , Jing Zhang , Didier Benoit , Chi-Hieu Pham , Julien Bert

The scale and quality of a dataset significantly impact the performance of deep models. However, acquiring large-scale annotated datasets is both a costly and time-consuming endeavor. To address this challenge, dataset expansion…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Haowei Zhu , Ling Yang , Jun-Hai Yong , Hongzhi Yin , Jiawei Jiang , Meng Xiao , Wentao Zhang , Bin Wang
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