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We investigate the relationship of resting-state fMRI functional connectivity estimated over long periods of time with time-varying functional connectivity estimated over shorter time intervals. We show that using Pearson's correlation to…

Neurons and Cognition · Quantitative Biology 2016-09-08 Richard F. Betzel , Makoto Fukushima , Ye He , Xi-Nian Zuo , Olaf Sporns

Modern neuroimaging technologies, combined with state-of-the-art data processing pipelines, have made it possible to collect longitudinal observations of an individual's brain connectome at different ages. It is of substantial scientific…

Applications · Statistics 2019-08-16 Lu Wang , Zhengwu Zhang

Stroke is one of the leading causes of disability worldwide. The efficacy of recovery is determined by a variety of factors, including patient adherence to rehabilitation programs. One way to increase patient adherence to their…

Human-Computer Interaction · Computer Science 2024-02-20 Alicia Ouskine , Adrian D. C. Chan , Fateme Rajabiyazdi

Stroke poses an immense public health burden and remains among the primary causes of death and disability worldwide. Emergent therapy is often precluded by late or indeterminate times of onset before initial clinical presentation. Rapid,…

Medical Physics · Physics 2021-04-16 Leeor Alon , Seena Dehkharghani

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

Neurons and Cognition · Quantitative Biology 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown

Recent experimental advances are producing an avalanche of data on both neural connectivity and neural activity. To take full advantage of these two emerging datasets we need a framework that links them, revealing how collective neural…

Neurons and Cognition · Quantitative Biology 2020-02-27 Gabriel Koch Ocker , Krešimir Josić , Eric Shea-Brown , Michael A. Buice

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

Modularity plays an important role in brain networks' architecture and influences its dynamics and the ability to integrate and segregate different modules of cerebral regions. Alterations in community structure are associated with several…

Neurons and Cognition · Quantitative Biology 2018-05-14 M. Cinelli , I. Echegoyen , M. Oliveira , S. Orellana , T. Gili

Currently, strokes are the leading cause of adult disability in the United States. Traditional treatment and rehabilitation options such as physical therapy and tissue plasminogen activator are limited in their effectiveness and ability to…

Signal Processing · Electrical Eng. & Systems 2020-08-20 Mohammad-Parsa Hosseini , Cecilia Hemingway , Jerard Madamba , Alexander McKee , Natalie Ploof , Jennifer Schuman , Elliot Voss

Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…

Neurons and Cognition · Quantitative Biology 2010-08-02 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Mariano Sigman

Living neural networks in our brains autonomously self-organize into large, complex architectures during early development to result in an organized and functional organic computational device. A key mechanism that enables the formation of…

Neural and Evolutionary Computing · Computer Science 2020-06-15 Guruprasad Raghavan , Cong Lin , Matt Thomson

Stroke is a leading cause of long-term disability and the second most common cause of death worldwide. Although acute treatments have advanced, recovery remains challenging and limited. Brain-computer interfaces (BCIs) have emerged as a…

Neurons and Cognition · Quantitative Biology 2025-10-10 Aniana Cruz , Marko Kuzmanoski , Gabriel Pires

Although recurrent neural networks (RNNs) trained on cognitive tasks have become a widely used framework for studying neural computation, the internal mechanisms by which RNNs switch between rhythms across multiple frequency bands, and how…

Neurons and Cognition · Quantitative Biology 2026-05-15 Yutaka Yamaguti , Shota Nakamura

Recurrent neural networks (RNNs) trained on compositional tasks can exhibit functional modularity, in which neurons can be clustered by activity similarity and participation in shared computational subtasks. Unlike brains, these RNNs do not…

Neurons and Cognition · Quantitative Biology 2023-10-12 Ziming Liu , Mikail Khona , Ila R. Fiete , Max Tegmark

Learning complex network dynamics is fundamental for understanding, modeling, and controlling real-world complex systems. Though great efforts have been made to predict the future states of nodes on networks, the capability of capturing…

Social and Information Networks · Computer Science 2025-03-04 Ruikun Li , Huandong Wang , Jinghua Piao , Qingmin Liao , Yong Li

A given neural network in the brain is involved in many different tasks. This implies that, when considering a specific task, the network's connectivity contains a component which is related to the task and another component which can be…

Neurons and Cognition · Quantitative Biology 2021-03-17 Friedrich Schuessler , Alexis Dubreuil , Francesca Mastrogiuseppe , Srdjan Ostojic , Omri Barak

Brain network is an important tool for understanding the brain, offering insights for scientific research and clinical diagnosis. Existing models for brain networks typically primarily focus on brain regions or overlook the complexity of…

Neurons and Cognition · Quantitative Biology 2024-05-30 Haoyu Hu , Hongrun Zhang , Chao Li

In many medical applications, interpretable models with high prediction performance are sought. Often, those models are required to handle semi-structured data like tabular and image data. We show how to apply deep transformation models…

Neural circuits comprise multiple interconnected regions, each with complex dynamics. The interplay between local and global activity is thought to underlie computational flexibility, yet the structure of multiregion neural activity and its…

Neurons and Cognition · Quantitative Biology 2025-01-09 David G. Clark , Manuel Beiran

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

Neurons and Cognition · Quantitative Biology 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa
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