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Clustering based on vibration responses, such as transmissibility functions (TFs), is promising in structural anomaly detection. However, most existing methods struggle to determine the optimal cluster number, handle high-dimensional…

Machine Learning · Computer Science 2025-10-21 Lin-Feng Mei , Wang-Ji Yan

Polymicrogyria (PMG) is a disorder of cortical organization mainly seen in children, which can be associated with seizures, developmental delay and motor weakness. PMG is typically diagnosed on magnetic resonance imaging (MRI) but some…

Computer Vision and Pattern Recognition · Computer Science 2022-11-24 Lingfeng Zhang , Nishard Abdeen , Jochen Lang

Although machine learning has transformed protein structure prediction of folded protein ground states with remarkable accuracy, intrinsically disordered proteins and regions (IDPs/IDRs) are defined by diverse and dynamical structural…

Biomolecules · Quantitative Biology 2025-04-01 Oufan Zhang , Zi Hao Liu , Julie D Forman-Kay , Teresa Head-Gordon

We propose the Deep Distance Measurement Method (DDMM) to improve retrieval accuracy in unsupervised multivariate time series similarity retrieval. DDMM enables learning of minute differences within states in the entire time series and…

Machine Learning · Computer Science 2026-03-16 Susumu Naito , Kouta Nakata , Yasunori Taguchi

DNA methylation (DNAme) is a critical component of the epigenetic regulatory machinery and aberrations in DNAme patterns occur in many diseases, such as cancer. Mapping and understanding DNAme profiles offers considerable promise for…

A Deep Autoencoder based content retrieval algorithm is proposed for prediction and differentiation of cancer types based on the presence of epigenetic patterns of DNA methylation identified in genetic regions known as CpG islands. The…

Quantitative Methods · Quantitative Biology 2018-10-08 Mohammed Khwaja , Melpomeni Kalofonou , Chris Toumazou

Representation learning focused on disentangling the underlying factors of variation in given data has become an important area of research in machine learning. However, most of the studies in this area have relied on datasets from the…

Machine Learning · Computer Science 2020-07-31 Ashis Pati , Siddharth Gururani , Alexander Lerch

Color Doppler echocardiography is a crucial tool for diagnosing mitral regurgitation (MR). Recent studies have explored intelligent methods for MR diagnosis to minimize user dependence and improve accuracy. However, these approaches often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Zhe Liu , Yuhao Huang , Lian Liu , Chengrui Zhang , Haotian Lin , Tong Han , Zhiyuan Zhu , Yanlin Chen , Yuerui Chen , Dong Ni , Zhongshan Gou , Xin Yang

Particle Marginal Metropolis-Hastings (PMMH) is a general approach to Bayesian inference when the likelihood is intractable, but can be estimated unbiasedly. Our article develops an efficient PMMH method that scales up better to higher…

Computation · Statistics 2023-05-10 David Gunawan , Pratiti Chatterjee , Robert Kohn

A maximally stable extreme region (MSER) analysis based convolutional neural network (CNN) for unified defect detection framework is proposed in this paper. Our proposed framework utilizes the generality and stability of MSER to generate…

Signal Processing · Electrical Eng. & Systems 2020-05-26 Zelin Deng , Xiaolong Yan , Shengjun Zhang , Colleen P. Bailey

EEG recordings contain rich information about neural activity but are subject to artifacts, noise, and superficial differences due to sensors, amplifiers, and filtering. Independent component analysis and automatic labeling of independent…

Machine Learning · Computer Science 2025-12-05 Austin Meek , Carlos H. Mendoza-Cardenas , Austin J. Brockmeier

Many researches demonstrated that the DNA methylation, which occurs in the context of a CpG, has strong correlation with diseases, including cancer. There is a strong interest in analyzing the DNA methylation data to find how to distinguish…

Genomics · Quantitative Biology 2020-01-29 Hong Yu , Zhanyu Ma

The Density Matrix Renormalization Group (DMRG) has become a powerful numerical method that can be applied to low-dimensional strongly correlated fermionic and bosonic systems. It allows for a very precise calculation of static, dynamic and…

Strongly Correlated Electrons · Physics 2008-11-26 Karen Hallberg

We present an implementation of the coherent dedispersion algorithm capable of dedispersing high-time-resolution radio observations to many different dispersion measures (DMs). This approach allows the removal of the dispersive effects of…

Instrumentation and Methods for Astrophysics · Physics 2016-07-05 C. G. Bassa , Z. Pleunis , J. W. T. Hessels

Motivation: Methods are needed to test pre-defined genomic regions such as promoters for differential methylation in genome-wide association studies, where the number of samples is limited and the data have large amounts of measurement…

Genomics · Quantitative Biology 2014-07-25 Duchwan Ryu , Hongyan Xu , Varghese George , Shaoyong Su , Xiaoling Wang , Huidong Shi , Robert H. Podolsky

Epigenetic alterations have an important role in the development of several types of cancer. Epigenetic studies generate a large amount of data, which makes it essential to develop novel models capable of dealing with large-scale data. In…

Machine Learning · Computer Science 2021-02-22 del Amor Rocío , Colomer Adrián , Monteagudo Carlos , Naranjo Valery

Clustering is one of the most widely used procedures in the analysis of microarray data, for example with the goal of discovering cancer subtypes based on observed heterogeneity of genetic marks between different tissues. It is well-known…

Methodology · Statistics 2009-04-21 Heng Lian

The development of cancer is largely driven by the gain or loss of subsets of the genome, promoting uncontrolled growth or disabling defenses against it. Identifying genomic regions whose DNA copy number deviates from the normal is…

Human multimodal emotion recognition (MER) aims to perceive human emotions via language, visual and acoustic modalities. Despite the impressive performance of previous MER approaches, the inherent multimodal heterogeneities still haunt and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-27 Yong Li , Yuanzhi Wang , Zhen Cui

Dataset distillation synthesizes a small dataset such that a model trained on this set approximates the performance of the original dataset. Recent studies on dataset distillation focused primarily on the design of the optimization process,…

Computer Vision and Pattern Recognition · Computer Science 2024-08-30 Shiguang Wang , Zhongyu Zhang , Jian Cheng