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The brain white matter consists of a set of tracts that connect distinct regions of the brain. Segmentation of these tracts is often needed for clinical and research studies. Diffusion-weighted MRI offers unique contrast to delineate these…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Hamza Kebiri , Ali Gholipour , Meritxell Bach Cuadra , Davood Karimi

It is common in anthropology and paleontology to address questions about extant and extinct species through the quantification of osteological features observable in micro-computed tomographic (micro-CT) scans. In cases where remains were…

Image and Video Processing · Electrical Eng. & Systems 2021-04-23 Amirsaeed Yazdani , Yung-Chen Sun , Nicholas B. Stephens , Timothy Ryan , Vishal Monga

Hodgkin lymphoma is an unusual type of lymphoma, arising from malignant B-cells. Morphological and immunohistochemical features of malignant cells and their distribution differ from other cancer types. Based on systematic tissue image…

Intravital microscopy is an essential tool that reveals behaviours of live cells under conditions close to natural physiological states. So far, although various approaches for imaging cells in vivo have been proposed, most require the use…

Biological Physics · Physics 2016-07-04 Kyoohyun Kim , Kibaek Choe , Inwon Park , Pilhan Kim , YongKeun Park

Cell instance segmentation is a new and challenging task aiming at joint detection and segmentation of every cell in an image. Recently, many instance segmentation methods have applied in this task. Despite their great success, there still…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Menghao Li , Wenquan Feng , Shuchang Lyu , Lijiang Chen , Qi Zhao

State-of-the-art (SOTA) methods for cell instance segmentation are based on deep learning (DL) semantic segmentation approaches, focusing on distinguishing foreground pixels from background pixels. In order to identify cell instances from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Peixian Liang , Yifan Ding , Yizhe Zhang , Jianxu Chen , Hao Zheng , Hongxiao Wang , Yejia Zhang , Guangyu Meng , Tim Weninger , Michael Niemier , X. Sharon Hu , Danny Z Chen

This abstract describes the segmentation system used to participate in the challenge ISIC 2017: Skin Lesion Analysis Towards Melanoma Detection. Several preprocessing techniques have been tested for three color representations (RGB, YCbCr…

Computer Vision and Pattern Recognition · Computer Science 2017-03-16 Juana M. Gutiérrez-Arriola , Marta Gómez-Álvarez , Victor Osma-Ruiz , Nicolás Sáenz-Lechón , Rubén Fraile

Hemorrhaging occurs in surgeries of all types, forcing surgeons to quickly adapt to the visual interference that results from blood rapidly filling the surgical field. Introducing automation into the crucial surgical task of hemostasis…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Albert J. Miao , Shan Lin , Jingpei Lu , Florian Richter , Benjamin Ostrander , Emily K. Funk , Ryan K. Orosco , Michael C. Yip

We present WBCBench 2026, an ISBI challenge and benchmark for automated WBC classification designed to stress-test algorithms under three key difficulties: (i) severe class imbalance across 13 morphologically fine-grained WBC classes, (ii)…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Xin Tian , Xudong Ma , Tianqi Yang , Alin Achim , Bartłomiej W Papież , Phandee Watanaboonyongcharoen , Nantheera Anantrasirichai

The precise categorization of white blood cell (WBC) is crucial for diagnosing blood-related disorders. However, manual analysis in clinical settings is time-consuming, labor-intensive, and prone to errors. Numerous studies have employed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Yuzhuo Chen , Zetong Chen , Yunuo An , Chenyang Lu , Xu Qiao

Many automatic skin lesion diagnosis systems use segmentation as a preprocessing step to diagnose skin conditions because skin lesion shape, border irregularity, and size can influence the likelihood of malignancy. This paper presents,…

Computer Vision and Pattern Recognition · Computer Science 2017-10-04 Bill S. Lin , Kevin Michael , Shivam Kalra , H. R. Tizhoosh

Red blood cell (RBC) deformation is the consequence of several diseases, including sickle cell anemia, which causes recurring episodes of pain and severe pronounced anemia. Monitoring patients with these diseases involves the observation of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Wilkie Delgado-Font , Miriela Escobedo-Nicot , Manuel González-Hidalgo , Silena Herold-Garcia , Antoni Jaume-i-Capó , Arnau Mir

The accurate classification of white blood cells and related blood components is crucial for medical diagnoses. While traditional manual examinations and automated hematology analyzers have been widely used, they are often slow and prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Alexander Kim , Ryan Kim

The locations of different mRNA molecules can be revealed by multiplexed in situ RNA detection. By assigning detected mRNA molecules to individual cells, it is possible to identify many different cell types in parallel. This in turn enables…

Information Theory · Computer Science 2023-12-08 Axel Andersson , Andrea Behanova , Carolina Wählby , Filip Malmberg

This work is about the semantic segmentation of skin lesion boundary and their attributes using Image-to-Image Translation with Conditional Adversarial Nets. Melanoma is a type of skin cancer that can be cured if detected in time.…

Image and Video Processing · Electrical Eng. & Systems 2021-02-02 Cristian Lazo

Wireless Capsule Endoscopy (WCE) is a relatively new technology to record the entire GI trace, in vivo. The large amounts of frames captured during an examination cause difficulties for physicians to review all these frames. The need for…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Omid Haji Maghsoudi

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the…

Quantitative Methods · Quantitative Biology 2020-03-03 Yan Ge , Philipp Rosendahl , Claudio Durán , Nicole Töpfner , Sara Ciucci , Jochen Guck , Carlo Vittorio Cannistraci

Vascular segmentation extracts blood vessels from images and serves as the basis for diagnosing various diseases, like ophthalmic diseases. Ophthalmologists often require high-resolution segmentation results for analysis, which leads to…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Yan Hu , Zhongxi Qiu , Dan Zeng , Li Jiang , Chen Lin , Jiang Liu