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Computational Cannula Microscopy (CCM) is a high-resolution widefield fluorescence imaging approach deep inside tissue, which is minimally invasive. Rather than using conventional lenses, a surgical cannula acts as a lightpipe for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ruipeng Guo , Zhimeng Pan , Andrew Taibi , Jason Shepherd , Rajesh Menon

Despite the prevalence of tabular datasets, few-shot learning remains under-explored within this domain. Existing few-shot methods are not directly applicable to tabular datasets due to varying column relationships, meanings, and…

Machine Learning · Computer Science 2023-11-17 Max Zhu , Katarzyna Kobalczyk , Andrija Petrovic , Mladen Nikolic , Mihaela van der Schaar , Boris Delibasic , Petro Lio

With the growing technology of photon-counting detectors (PCD), spectral CT is a widely concerned topic which has the potential of material differentiation. However, due to some non-ideal factors such as cross talk and pulse pile-up of the…

Medical Physics · Physics 2020-07-21 Ao Zheng , Hongkai Yang , Li Zhang , Yuxiang Xing

Ultrasound computed tomography (USCT) is an emerging imaging modality for breast imaging that can produce quantitative images that depict the acoustic properties of tissues. Computer-simulation studies, also known as virtual imaging trials,…

Medical Physics · Physics 2022-06-24 Fu Li , Umberto Villa , Seonyeong Park , Mark A. Anastasio

Purpose: Optoacoustic tomography (OAT) is inherently a three-dimensional (3D) inverse problem. However, most studies of OAT image reconstruction still employ two-dimensional (2D) imaging models. One important reason is because 3D image…

Medical Physics · Physics 2013-04-09 Kun Wang , Chao Huang , Yu-Jiun Kao , Cheng-Ying Chou , Alexander A. Oraevsky , Mark A. Anastasio

Optical coherence tomography (OCT) is capable of non-destructively obtaining cross-sectional information of samples with micrometer spatial resolution, which plays an important role in ophthalmology and endovascular medicine. Measuring OCT…

Medical Physics · Physics 2023-11-30 Yang Jianlong , Zhang Haoran , Liu Chang , Gu Chengfu

Depth sectioning in reflection microscopy has predominantly relied on temporal coherence gating. Here we show that volumetric reflection tomography at diffraction-limited resolution can be achieved under monochromatic illumination by…

The photoacoustic tomography (PAT) is a hybrid modality that combines the optics and acoustics to obtain high resolution and high contrast imaging of heterogeneous media. In this work, our objective is to study the inverse problem in the…

Numerical Analysis · Mathematics 2021-05-26 Hongkai Zhao , Yimin Zhong

Computed tomography (CT) provides high spatial resolution visualization of 3D structures for scientific and clinical applications. Traditional analytical/iterative CT reconstruction algorithms require hundreds of angular data samplings, a…

Image and Video Processing · Electrical Eng. & Systems 2024-11-14 Di Xu , Yang Yang , Hengjie Liu , Qihui Lyu , Martina Descovich , Dan Ruan , Ke Sheng

Quantitative photoacoustic computed tomography (qPACT) is an emerging medical imaging modality that carries the promise of high-contrast, fine-resolution imaging of clinically relevant quantities like hemoglobin concentration and…

Medical Physics · Physics 2024-10-15 Evan Scope Crafts , Mark A. Anastasio , Umberto Villa

Three-dimensional (3D) ultrasound provides enhanced visualization of the carotid artery (CA) anatomy and volumetric flow, offering improved accuracy for cardiovascular diagnosis and monitoring. However, fully populated matrix transducers…

Optoacoustic tomography (OAT) is a promising modality for breast cancer diagnosis because tumor angiogenesis and, potentially, hypoxia can be visualized using quantitative OAT (qOAT) techniques. Clinically meaningful inference generally…

Medical Physics · Physics 2025-10-02 Seonyeong Park , Gangwon Jeong , Umberto Villa , Mark A. Anastasio

Photoacoustic tomography (PAT) is a novel and rapidly promising technique in the field of medical imaging, based on the generation of acoustic waves inside an object of interest by stimulating non-ionizing laser pulses. This acoustic wave…

Analysis of PDEs · Mathematics 2022-02-08 Hyungyeong Jung , Sunghwan Moon

Single-shot ptychography is a quantitative phase imaging method wherein overlapping beams of light arranged in a grid pattern simultaneously illuminate a sample, allowing a full ptychographic dataset to be collected in a single shot. It is…

Limited-angle computed tomography (LACT) offers improved temporal resolution and reduced radiation dose for cardiac imaging, but suffers from severe artifacts due to truncated projections. To address the ill-posedness of LACT…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Yu Shi , Shuyi Fan , Changsheng Fang , Shuo Han , Haodong Li , Li Zhou , Bahareh Morovati , Dayang Wang , Hengyong Yu

Photoacoustic imaging (PAI) uniquely combines the advantages of optical contrast with deep tissue penetration capability of acoustic waves, enabling imaging at depths of several centimeters. Conventional photoacoustic imaging methods have…

Applied Physics · Physics 2026-02-24 Xingchi Yan , Siyuan Song , Hanxun Jin

Capturing depth and reflectivity images at low light levels from active illumination of a scene has wide-ranging applications. Conventionally, even with single-photon detectors, hundreds of photon detections are needed at each pixel to…

Applications · Statistics 2026-03-12 Dongeek Shin , Ahmed Kirmani , Vivek K Goyal , Jeffrey H. Shapiro

We introduce a method and a 3D-camera for single-shot 3D shape measurement, with unprecedented features: The 3D-camera does not rely on pattern codification and acquires object surfaces at the theoretical limit of the information…

Optics · Physics 2017-10-11 Florian Willomitzer , Gerd Häusler

Photoacoustic Microscopy (PAM) images integrating the advantages of optical contrast and acoustic resolution have been widely used in brain studies. However, there exists a trade-off between scanning speed and image resolution. Compared…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Kai Pan , Linyang Li , Li Lin , Pujin Cheng , Junyan Lyu , Lei Xi , Xiaoyin Tang

Photoacoustic (PA) waves are strongly distorted and attenuated in skull bone. To study these effects on PA imaging, we designed and 3D-printed tissue-mimicking phantoms of human skull. We present a comparison of results in phantom and ex…

Medical Physics · Physics 2025-02-18 Hannah Linde , Saskia Menzer , Jan Laufer , Thomas Kirchner