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Karyotyping is an important procedure to assess the possible existence of chromosomal abnormalities. However, because of the non-rigid nature, chromosomes are usually heavily curved in microscopic images and such deformed shapes hinder the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Sunyi Zheng , Jingxiong Li , Zhongyi Shui , Chenglu Zhu , Yunlong Zhang , Pingyi Chen , Lin Yang

Quantitative imaging methods, such as magnetic resonance fingerprinting (MRF), aim to extract interpretable pathology biomarkers by estimating biophysical tissue parameters from signal evolutions. However, the pattern-matching algorithms or…

The Masked Autoencoder (MAE) has recently demonstrated effectiveness in pre-training Vision Transformers (ViT) for analyzing natural images. By reconstructing complete images from partially masked inputs, the ViT encoder gathers contextual…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Badhan Kumar Das , Gengyan Zhao , Han Liu , Thomas J. Re , Dorin Comaniciu , Eli Gibson , Andreas Maier

This paper shows that masked autoencoders (MAE) are scalable self-supervised learners for computer vision. Our MAE approach is simple: we mask random patches of the input image and reconstruct the missing pixels. It is based on two core…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Kaiming He , Xinlei Chen , Saining Xie , Yanghao Li , Piotr Dollár , Ross Girshick

Natural systems with emergent behaviors often organize along low-dimensional subsets of high-dimensional spaces. For example, despite the tens of thousands of genes in the human genome, the principled study of genomics is fruitful because…

Variational autoencoders are powerful algorithms for identifying dominant latent structure in a single dataset. In many applications, however, we are interested in modeling latent structure and variation that are enriched in a target…

Machine Learning · Computer Science 2019-02-14 Abubakar Abid , James Zou

The cosmic microwave background power spectra are a primary window into the early universe. However, achieving interpretable, likelihood-compatible compression and fast inference under weak model assumptions remains challenging. We propose…

Cosmology and Nongalactic Astrophysics · Physics 2025-11-03 Tian-Yang Sun , Tian-Nuo Li , He Wang , Jing-Fei Zhang , Xin Zhang

Electrocardiogram (ECG) analysis is a fundamental tool for diagnosing cardiovascular conditions, yet anomaly detection in ECG signals remains challenging due to their inherent complexity and variability. We propose Multi-scale Masked…

Machine Learning · Computer Science 2025-02-11 Ya Zhou , Yujie Yang , Jianhuang Gan , Xiangjie Li , Jing Yuan , Wei Zhao

Defining and separating cancer subtypes is essential for facilitating personalized therapy modality and prognosis of patients. The definition of subtypes has been constantly recalibrated as a result of our deepened understanding. During…

Machine Learning · Computer Science 2022-07-21 Zheng Chen , Ziwei Yang , Lingwei Zhu , Guang Shi , Kun Yue , Takashi Matsubara , Shigehiko Kanaya , MD Altaf-Ul-Amin

The use of deep learning to undertake shape analysis of the complexities of the human head holds great promise. However, there have traditionally been a number of barriers to accurate modelling, especially when operating on both a global…

Separating shared and independent features is crucial for multi-phase contrast-enhanced (CE) MRI synthesis. However, existing methods use deep autoencoder generators with low parameter efficiency and lack interpretable training strategies.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Xiaoyan Kui , Qianmu Xiao , Qqinsong Li , Zexin Ji , JIelin Zhang , Beiji Zou

Self-supervised models allow (pre-)training on unlabeled data and therefore have the potential to overcome the need for large annotated cohorts. One leading self-supervised model is the masked autoencoder (MAE) which was developed on…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Daniel M. Lang , Eli Schwartz , Cosmin I. Bercea , Raja Giryes , Julia A. Schnabel

Masked AutoEncoder (MAE) has revolutionized the field of self-supervised learning with its simple yet effective masking and reconstruction strategies. However, despite achieving state-of-the-art performance across various downstream vision…

Computer Vision and Pattern Recognition · Computer Science 2023-12-11 Xiaoyu Yue , Lei Bai , Meng Wei , Jiangmiao Pang , Xihui Liu , Luping Zhou , Wanli Ouyang

A clear need for automatic anomaly detection applied to automotive testing has emerged as more and more attention is paid to the data recorded and manual evaluation by humans reaches its capacity. Such real-world data is massive, diverse,…

Machine Learning · Computer Science 2024-11-22 Lucas Correia , Jan-Christoph Goos , Philipp Klein , Thomas Bäck , Anna V. Kononova

Masked autoencoders (MAEs) are increasingly applied to electronic health records (EHR) for learning general-purpose representations that support diverse clinical tasks. However, existing approaches typically rely on uniform random masking,…

Machine Learning · Computer Science 2025-12-08 Rajna Fani , Rafi Al Attrach , David Restrepo , Yugang Jia , Leo Anthony Celi , Peter Schüffler

Masked Image Modeling (MIM) methods, like Masked Autoencoders (MAE), efficiently learn a rich representation of the input. However, for adapting to downstream tasks, they require a sufficient amount of labeled data since their rich features…

Computer Vision and Pattern Recognition · Computer Science 2023-09-15 Johannes Lehner , Benedikt Alkin , Andreas Fürst , Elisabeth Rumetshofer , Lukas Miklautz , Sepp Hochreiter

Masked Autoencoder (MAE) is a self-supervised approach for representation learning, widely applicable to a variety of downstream tasks in computer vision. In spite of its success, it is still not fully uncovered what and how MAE exactly…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Jeongwoo Shin , Inseo Lee , Junho Lee , Joonseok Lee

Mutational signature analysis has emerged as a powerful method for uncovering the underlying biological processes driving cancer development. However, the signature extraction process, typically performed using non-negative matrix…

Applications · Statistics 2026-02-27 Ida Egendal , Rasmus Froberg Brøndum , Dan J Woodcock , Christopher Yau , Martin Bøgsted

Cryo-electron microscopy (cryo-EM) has revolutionized experimental protein structure determination. Despite advances in high resolution reconstruction, a majority of cryo-EM experiments provide either a single state of the studied…

Masked Autoencoder (MAE) has recently been shown to be effective in pre-training Vision Transformers (ViT) for natural image analysis. By reconstructing full images from partially masked inputs, a ViT encoder aggregates contextual…

Image and Video Processing · Electrical Eng. & Systems 2023-04-24 Lei Zhou , Huidong Liu , Joseph Bae , Junjun He , Dimitris Samaras , Prateek Prasanna
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