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Related papers: Post-Selection Inference for the Cox Model with In…

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It is known that the Thresholded Lasso (TL), SCAD or MCP correct intrinsic estimation bias of the Lasso. In this paper we propose an alternative method of improving the Lasso for predictive models with general convex loss functions which…

Statistics Theory · Mathematics 2021-01-26 Piotr Pokarowski , Wojciech Rejchel , Agnieszka Soltys , Michal Frej , Jan Mielniczuk

Background: The development of classification methods for personalized medicine is highly dependent on the identification of predictive genetic markers. In survival analysis it is often necessary to discriminate between influential and…

Methodology · Statistics 2018-02-27 Thomas Welchowski , Verena Zuber , Matthias Schmid

This paper studies the inference of the regression coefficient matrix under multivariate response linear regressions in the presence of hidden variables. A novel procedure for constructing confidence intervals of entries of the coefficient…

Methodology · Statistics 2022-01-21 Xin Bing , Wei Cheng , Huijie Feng , Yang Ning

We give a finite-sample analysis of predictive inference procedures after model selection in regression with random design. The analysis is focused on a statistically challenging scenario where the number of potentially important…

Statistics Theory · Mathematics 2009-08-26 Hannes Leeb

The proportional hazards (PH) model is arguably one of the most popular models used to analyze time to event data arising from clinical trials and longitudinal studies, among many others. In many such studies, the event time of interest is…

We consider varying coefficient Cox models with high-dimensional covariates. We apply the group Lasso method to these models and propose a variable selection procedure. Our procedure copes with variable selection and structure…

Statistics Theory · Mathematics 2016-07-20 Toshio Honda , Ryota Yabe

Thomas' partial likelihood estimator of regression parameters is widely used in the analysis of nested case-control data with Cox's model. This paper proposes a new estimator of the regression parameters, which is consistent and…

Statistics Theory · Mathematics 2007-06-13 Kani Chen

Predicting an individual's risk of experiencing a future clinical outcome is a statistical task with important consequences for both practicing clinicians and public health experts. Modern observational databases such as electronic health…

In multi-center clinical research, privacy regulations often prohibit pooling individual-level records, complicating the analysis of time-to-event data. Current federated survival methods frequently require iterative communication or rely…

Applications · Statistics 2026-03-12 Hyojung Jang , Malcolm Risk , Yaojie Wang , Norrina Bai Allen , Xu Shi , Lili Zhao

We consider inference for M-estimators after model selection using a sparsity-inducing penalty. While existing methods for this task require bespoke inference procedures, we propose a simpler approach, which relies on two insights: (i)…

Methodology · Statistics 2026-01-21 Ronan Perry , Snigdha Panigrahi , Daniela Witten

IMPORTANCE: Feature selection with respect to time-to-event outcomes is one of the fundamental problems in clinical trials and biomarker discovery studies. But it's unclear which statistical methods should be used when sample size is small…

Methodology · Statistics 2022-10-17 Rong Lu

In survival analysis, the lifetime under study is not always observed. In certain applications, for some individuals, the value of the lifetime is only known to be smaller or larger than some random duration. This framework represent an…

Statistics Theory · Mathematics 2020-02-25 Laurent Bordes , Maria Carmen Pardo , Christian Paroissin , Valentin Patilea

We tackle the problem of the estimation of a vector of means from a single vector-valued observation $y$. Whereas previous work reduces the size of the estimates for the largest (absolute) sample elements via shrinkage (like James-Stein) or…

Methodology · Statistics 2015-03-19 Stephen Reid , Jonathan Taylor , Robert Tibshirani

This work addresses the problem of conducting valid inference for additive and linear mixed models after model selection. One possible solution to overcome overconfident inference results after model selection is selective inference, which…

Methodology · Statistics 2020-12-22 David Rügamer , Philipp F. M. Baumann , Sonja Greven

We consider the situation of estimating Cox regression in which some covariates are subject to missing, and there exists additional information (including observed event time, censoring indicator and fully observed covariates) which may be…

Methodology · Statistics 2017-10-16 Chiu-Hsieh Hsu , Mandi Yu

Changepoint detection methods are used in many areas of science and engineering, e.g., in the analysis of copy number variation data, to detect abnormalities in copy numbers along the genome. Despite the broad array of available tools,…

Methodology · Statistics 2018-12-11 Sangwon Hyun , Kevin Lin , Max G'Sell , Ryan J. Tibshirani

We propose the variable selection procedure incorporating prior constraint information into lasso. The proposed procedure combines the sample and prior information, and selects significant variables for responses in a narrower region where…

Methodology · Statistics 2011-02-19 Shurong Zheng , Guodong Song , Ning-Zhong Shi

Maximum approximate Bernstein likelihood estimates of the baseline density function and the regression coefficients in the proportional hazard regression models based on interval-censored event time data are proposed. This results in not…

Methodology · Statistics 2020-12-25 Zhong Guan

Consider the problem of estimating average treatment effects when a large number of covariates are used to adjust for possible confounding through outcome regression and propensity score models. The conventional approach of model building…

Statistics Theory · Mathematics 2018-01-31 Zhiqiang Tan

We study the absolute penalized maximum partial likelihood estimator in sparse, high-dimensional Cox proportional hazards regression models where the number of time-dependent covariates can be larger than the sample size. We establish…

Statistics Theory · Mathematics 2013-06-21 Jian Huang , Tingni Sun , Zhiliang Ying , Yi Yu , Cun-Hui Zhang