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Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular processes by enabling gene expression analysis at the individual cell level. Clustering allows for the identification of cell types and the further…

Machine Learning · Computer Science 2025-06-03 Ziwen Wang

Single-Program-Multiple-Data (SPMD) parallelism has recently been adopted to train large deep neural networks (DNNs). Few studies have explored its applicability on heterogeneous clusters, to fully exploit available resources for large…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-12 Shiwei Zhang , Lansong Diao , Chuan Wu , Zongyan Cao , Siyu Wang , Wei Lin

On June 25th, 2018, Huang et al. published a computational method SAVER on Nature Methods for imputing dropout gene expression levels in single cell RNA sequencing (scRNA-seq) data. Huang et al. performed a set of comprehensive benchmarking…

Applications · Statistics 2019-08-21 Wei Vivian Li , Jingyi Jessica Li

Visualization methods based on the nearest neighbor graph, such as t-SNE or UMAP, are widely used for visualizing high-dimensional data. Yet, these approaches only produce meaningful results if the nearest neighbors themselves are…

Machine Learning · Computer Science 2024-06-06 Jan Niklas Böhm , Philipp Berens , Dmitry Kobak

This paper presents a new, parallel implementation of clustering and demonstrates its utility in greatly speeding up the process of identifying homologous proteins. Clustering is a technique to reduce the number of comparison needed to find…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-29 Stuart Byma , Akash Dhasade , Adrian Altenhoff , Christophe Dessimoz , James R. Larus

The massive quantities of genomic data being made available through gene sequencing techniques are enabling breakthroughs in genomic science in many areas such as medical advances in the diagnosis and treatment of diseases. Analyzing this…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-24 Wayne Joubert , James Nance , Sharlee Climer , Deborah Weighill , Daniel Jacobson

Human placenta is a complex and heterogeneous organ interfacing between the mother and the fetus that supports fetal development. Alterations to placental structural components are associated with various pregnancy complications. To reveal…

Tissues and Organs · Quantitative Biology 2020-08-11 Hui Li , Qianhui Huang , Yu Liu , Lana X Garmire

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

Genomics · Quantitative Biology 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Filip Lux , Petr Matula

Pansharpening is a fundamental issue in remote sensing field. This paper proposes a side information partially guided convolutional sparse coding (SCSC) model for pansharpening. The key idea is to split the low resolution multispectral…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Shuang Xu , Jiangshe Zhang , Kai Sun , Zixiang Zhao , Lu Huang , Junmin Liu , Chunxia Zhang

We propose a novel method, scTree, for single-cell Tree Variational Autoencoders, extending a hierarchical clustering approach to single-cell RNA sequencing data. scTree corrects for batch effects while simultaneously learning a…

Machine Learning · Computer Science 2024-07-11 Moritz Vandenhirtz , Florian Barkmann , Laura Manduchi , Julia E. Vogt , Valentina Boeva

We introduce an improved unsupervised clustering protocol specially suited for large-scale structured data. The protocol follows three steps: a dimensionality reduction of the data, a density estimation over the low dimensional…

Machine Learning · Computer Science 2019-11-05 Joan Garriga , Frederic Bartumeus

Scene Coordinate Regression (SCR) is a visual localization technique that utilizes deep neural networks (DNN) to directly regress 2D-3D correspondences for camera pose estimation. However, current SCR methods often face challenges in…

Robotics · Computer Science 2025-08-26 Kuan Xu , Zeyu Jiang , Haozhi Cao , Shenghai Yuan , Chen Wang , Lihua Xie

Sequence set is a widely-used type of data source in a large variety of fields. A typical example is protein structure prediction, which takes an multiple sequence alignment (MSA) as input and aims to infer structural information from it.…

Biomolecules · Quantitative Biology 2019-06-27 Fusong Ju , Jianwei Zhu , Guozheng Wei , Qi Zhang , Shiwei Sun , Dongbo Bu

In this paper, we develop a method for unsupervised clustering of two-way (matrix) data by combining two recent innovations from different fields: the Sparse Subspace Clustering (SSC) algorithm [10], which groups points coming from a union…

Machine Learning · Computer Science 2015-02-24 Eric Kernfeld , Shuchin Aeron , Misha Kilmer

Cross-camera data association is one of the cornerstones of the multi-camera computer vision field. Although often integrated into detection and tracking tasks through architecture design and loss definition, it is also recognized as an…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Đorđe Nedeljković

Predicting a complete spatially correlated field from sparse observations is a fundamental challenge in spatial statistics and environmental modelling. Classical interpolation methods such as Kriging rely on Gaussian process assumptions and…

Machine Learning · Statistics 2026-05-29 Daniel Tinoco , Raquel Menezes , Carlos Baquero , Alexandra Silva

The dimensionality reduction has been widely introduced to use the high-dimensional data for regression, classification, feature analysis, and visualization. As the one technique of dimensionality reduction, a stochastic neighbor embedding…

Computer Vision and Pattern Recognition · Computer Science 2020-12-03 Motoshi Abe , Junichi Miyao , Takio Kurita

Parallel coordinates plot (PCP) is an excellent tool for multivariate visualization and analysis, but it may fail to reveal inherent structures for datasets with a large number of items. In this paper, we propose a suite of novel…

Graphics · Computer Science 2013-11-05 Xin Zhao , Bo Li

Spectral Clustering is a popular technique to split data points into groups, especially for complex datasets. The algorithms in the Spectral Clustering family typically consist of multiple separate stages (such as similarity matrix…

Machine Learning · Computer Science 2019-11-04 Yifei Wang , Rui Liu , Yong Chen , Hui Zhangs , Zhiwen Ye
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