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MOTIVATION: Proteins fold into complex structures that are crucial for their biological functions. Experimental determination of protein structures is costly and therefore limited to a small fraction of all known proteins. Hence, different…

Biomolecules · Quantitative Biology 2018-04-18 David Menéndez Hurtado , Karolis Uziela , Arne Elofsson

Parameter inference and uncertainty quantification are important steps when relating mathematical models to real-world observations, and when estimating uncertainty in model predictions. However, methods for doing this can be…

Quantitative Methods · Quantitative Biology 2025-08-27 Michael J. Plank , Matthew J. Simpson

Determinantal Point Processes (DPPs) are a family of probabilistic models that have a repulsive behavior, and lend themselves naturally to many tasks in machine learning where returning a diverse set of objects is important. While there are…

Statistics Theory · Mathematics 2017-03-03 John Urschel , Victor-Emmanuel Brunel , Ankur Moitra , Philippe Rigollet

Foundation models and their checkpoints have significantly advanced deep learning, boosting performance across various applications. However, fine-tuned models often struggle outside their specific domains and exhibit considerable…

Deep learning models have been widely used during the last decade due to their outstanding learning and abstraction capacities. However, one of the main challenges any scientist has to face using deep learning models is to establish the…

Machine Learning · Computer Science 2025-04-22 Luis Balderas , Miguel Lastra , José M. Benítez

While data are the primary fuel for machine learning models, they often suffer from missing values, especially when collected in real-world scenarios. However, many off-the-shelf machine learning models, including artificial neural network…

Statistical models and methods for determinantal point processes (DPPs) seem largely unexplored. We demonstrate that DPPs provide useful models for the description of spatial point pattern datasets where nearby points repel each other. Such…

Statistics Theory · Mathematics 2016-04-28 Frédéric Lavancier , Jesper Møller , Ege Rubak

The paper focuses on Image Compression, explaining efficient approaches based on Frequent Pattern Mining(FPM). The proposed compression mechanism is based on clustering similar pixels in the image and thus using cluster identifiers in image…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Avinash Kadimisetty , C. Oswald , B. Sivalselvan

Existing ML models are known to be highly over-parametrized, and use significantly more resources than required for a given task. Prior work has explored compressing models offline, such as by distilling knowledge from larger models into…

Machine Learning · Computer Science 2022-05-17 Julian Knodt

Weight pruning has been widely acknowledged as a straightforward and effective method to eliminate redundancy in Deep Neural Networks (DNN), thereby achieving acceleration on various platforms. However, most of the pruning techniques are…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Xiaolong Ma , Wei Niu , Tianyun Zhang , Sijia Liu , Sheng Lin , Hongjia Li , Xiang Chen , Jian Tang , Kaisheng Ma , Bin Ren , Yanzhi Wang

Conformal prediction is a non-parametric technique for constructing prediction intervals or sets from arbitrary predictive models under the assumption that the data is exchangeable. It is popular as it comes with theoretical guarantees on…

Machine Learning · Statistics 2025-12-01 Jase Clarkson , Wenkai Xu , Mihai Cucuringu , Yvik Swan , Gesine Reinert

In pattern mining, the main challenge is the exponential explosion of the set of patterns. Typically, to solve this problem, a constraint for pattern selection is introduced. One of the first constraints proposed in pattern mining is…

Artificial Intelligence · Computer Science 2015-06-17 Aleksey Buzmakov , Sergei O. Kuznetsov , Amedeo Napoli

Subset selection for multiple linear regression aims to construct a regression model that minimizes errors by selecting a small number of explanatory variables. Once a model is built, various statistical tests and diagnostics are conducted…

Machine Learning · Statistics 2020-09-04 Seokhyun Chung , Young Woong Park , Taesu Cheong

Self-supervised speech representation learning (SSL) has shown to be effective in various downstream tasks, but SSL models are usually large and slow. Model compression techniques such as pruning aim to reduce the model size and computation…

Computation and Language · Computer Science 2023-03-01 Yifan Peng , Kwangyoun Kim , Felix Wu , Prashant Sridhar , Shinji Watanabe

Model pruning has gained traction as a promising defense strategy against backdoor attacks in deep learning. However, existing pruning-based approaches often fall short in accurately identifying and removing the specific parameters…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Kealan Dunnett , Reza Arablouei , Dimity Miller , Volkan Dedeoglu , Raja Jurdak

Conformal prediction is a framework for uncertainty quantification that constructs prediction sets for previously unseen data, guaranteeing coverage of the true label with a specified probability. However, the efficiency of these prediction…

Machine Learning · Computer Science 2026-01-06 Erfan Hajihashemi , Yanning Shen

Process model quality has been an area of considerable research efforts. In this context, the correctness-by-construction principle of change patterns provides promising perspectives. However, using change patterns for model creation…

Software Engineering · Computer Science 2015-11-13 Barbara Weber , Jakob Pinggera , Victoria Torres , Manfred Reichert

Computational protein-protein interaction (PPI) prediction techniques can contribute greatly in reducing time, cost and false-positive interactions compared to experimental approaches. Sequence is one of the key and primary information of…

Machine Learning · Computer Science 2022-03-29 Soumyadeep Debnath , Ayatullah Faruk Mollah

Predictive parity (PP), also known as sufficiency, is a core definition of algorithmic fairness essentially stating that model outputs must have the same interpretation of expected outcomes regardless of group. Testing and satisfying PP is…

Methodology · Statistics 2023-06-01 Cyrus DiCiccio , Brian Hsu , YinYin Yu , Preetam Nandy , Kinjal Basu

Universal probabilistic programming systems (PPSs) provide a powerful framework for specifying rich probabilistic models. They further attempt to automate the process of drawing inferences from these models, but doing this successfully is…

Machine Learning · Statistics 2020-07-17 Yuan Zhou , Hongseok Yang , Yee Whye Teh , Tom Rainforth