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Sensory neuroprostheses are emerging as a promising technology to restore lost sensory function or augment human capabilities. However, sensations elicited by current devices often appear artificial and distorted. Although current models…

Machine Learning · Computer Science 2022-10-20 Jacob Granley , Lucas Relic , Michael Beyeler

Human-in-the-loop optimization (HILO) is a promising approach for personalizing visual prostheses by iteratively refining stimulus parameters based on user feedback. Previous work demonstrated HILO's efficacy in simulation, but its…

Machine Learning · Computer Science 2025-04-29 Eirini Schoinas , Adyah Rastogi , Anissa Carter , Jacob Granley , Michael Beyeler

Decoding visual stimuli from neural population activity is crucial for understanding the brain and for applications in brain-machine interfaces. However, such biological data is often scarce, particularly in primates or humans, where…

Machine Learning · Computer Science 2025-10-24 Jan Sobotka , Luca Baroni , Ján Antolík

Neural decoding may be formulated as dynamic state estimation (filtering) based on point process observations, a generally intractable problem. Numerical sampling techniques are often practically useful for the decoding of real neural data.…

Neurons and Cognition · Quantitative Biology 2019-01-15 Yuval Harel , Ron Meir , Manfred Opper

Tuning active prostheses for people with amputation is time-consuming and relies on metrics that may not fully reflect user needs. We introduce a human-in-the-loop optimization (HILO) approach that leverages direct user preferences to…

Optimal input settings vary across users due to differences in motor abilities and personal preferences, which are typically addressed by manual tuning or calibration. Although human-in-the-loop optimization has the potential to identify…

Human-Computer Interaction · Computer Science 2025-03-10 Yi-Chi Liao , Paul Streli , Zhipeng Li , Christoph Gebhardt , Christian Holz

The decoding of brain signals recorded via, e.g., an electroencephalogram, using machine learning is key to brain-computer interfaces (BCIs). Stimulation parameters or other experimental settings of the BCI protocol typically are chosen…

Neurons and Cognition · Quantitative Biology 2021-09-14 Jan Sosulski , David Hübner , Aaron Klein , Michael Tangermann

Existing prescriptive compression strategies used in hearing aid fitting are designed based on gain averages from a group of users which are not necessarily optimal for a specific user. Nearly half of hearing aid users prefer settings that…

Audio and Speech Processing · Electrical Eng. & Systems 2020-07-02 Nasim Alamdari , Edward Lobarinas , Nasser Kehtarnavaz

Retinal implants aim to restore functional vision despite photoreceptor degeneration, yet are fundamentally constrained by low resolution electrode arrays and patient-specific perceptual distortions. Most deployed encoders rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Henning Konermann , Yuli Wu , Emil Mededovic , Volkmar Schulz , Peter Walter , Johannes Stegmaier

Experiments that study neural encoding of stimuli at the level of individual neurons typically choose a small set of features present in the world --- contrast and luminance for vision, pitch and intensity for sound --- and assemble a…

Machine Learning · Statistics 2016-11-22 Xin , Chen , Jeffrey M Beck , John M Pearson

Deep brain stimulation (DBS) has the potential to improve the quality of life of people with a variety of neurological diseases. A key challenge in DBS is in the placement of a stimulation electrode in the anatomical location that maximizes…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Camilo Bermudez , William Rodriguez , Yuankai Huo , Allison E. Hainline , Rui Li , Robert Shults , Pierre D. DHaese , Peter E. Konrad , Benoit M. Dawant , Bennett A. Landman

Implantable retinal prostheses offer a promising solution to restore partial vision by circumventing damaged photoreceptor cells in the retina and directly stimulating the remaining functional retinal cells. However, the information…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yuli Wu , Julian Wittmann , Peter Walter , Johannes Stegmaier

Synergies have been adopted in prosthetic limb applications to reduce complexity of design, but typically involve a single synergy setting for a population and ignore individual preference or adaptation capacity. However, personalization of…

Robotics · Computer Science 2020-02-20 Ricardo Garcia-Rosas , Ying Tan , Denny Oetomo , Chris Manzie , Peter Choong

Neuroprosthetic brain-computer interfaces function via an algorithm which decodes neural activity of the user into movements of an end effector, such as a cursor or robotic arm. In practice, the decoder is often learned by updating its…

Machine Learning · Statistics 2016-09-28 Josh Merel , David Carlson , Liam Paninski , John P. Cunningham

The application of closed-loop approaches in systems neuroscience and therapeutic stimulation holds great promise for revolutionizing our understanding of the brain and for developing novel neuromodulation therapies to restore lost…

Signal Processing · Electrical Eng. & Systems 2021-10-12 Bingzhao Zhu , Uisub Shin , Mahsa Shoaran

Realizing high-throughput aberration-corrected Scanning Transmission Electron Microscopy (STEM) exploration of atomic structures requires rapid tuning of multipole probe correctors while compensating for the inevitable drift of the optical…

Machine Learning · Computer Science 2026-01-28 Utkarsh Pratiush , Austin Houston , Richard Liu , Gerd Duscher , Sergei Kalinin

Cortical visual prostheses aim to restore sight by electrically stimulating neurons in early visual cortex (V1). With the emergence of high-density and flexible neural interfaces, electrode placement within three-dimensional cortex has…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Galen Pogoncheff , Alvin Wang , Jacob Granley , Michael Beyeler

Personalization of the amplification function of hearing aids has been shown to be of benefit to hearing aid users in previous studies. Several machine learning-based personalization approaches have been introduced in the literature. This…

Audio and Speech Processing · Electrical Eng. & Systems 2024-06-17 Aoxin Ni , Edward Lobarinas , Nasser Kehtarnavaz

Understanding brain function, constructing computational models and engineering neural prosthetics require assessing two problems, namely encoding and decoding, but their relation remains controversial. For decades, the encoding problem has…

Neurons and Cognition · Quantitative Biology 2017-01-16 Hugo Gabriel Eyherabide

Effective visual brain-machine interfaces (BMI) is based on reliable and stable EEG biomarkers. However, traditional adaptive filter-based approaches may suffer from individual variations in EEG signals, while deep neural network-based…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Junwen Luo , Chengyong Jiang , Qingyuan Chen , Dongqi Han , Yansen Wang , Biao Yan , Dongsheng Li , Jiayi Zhang
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