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Explainable ML for molecular toxicity prediction is a promising approach for efficient drug development and chemical safety. A predictive ML model of toxicity can reduce experimental cost and time while mitigating ethical concerns by…

Quantitative Methods · Quantitative Biology 2022-04-15 Bhanushee Sharma , Vijil Chenthamarakshan , Amit Dhurandhar , Shiranee Pereira , James A. Hendler , Jonathan S. Dordick , Payel Das

Meta-learning is a popular approach for learning new tasks with limited data by leveraging the commonalities among different tasks. However, meta-learned models can perform poorly when context data is too limited, or when data is drawn from…

Machine Learning · Computer Science 2026-04-10 Young-Jin Park , Cesar Almecija , Apoorva Sharma , Navid Azizan

The clinical trial process, a critical phase in drug development, is essential for developing new treatments. The primary goal of interventional clinical trials is to evaluate the safety and efficacy of drug-based treatments for specific…

Machine Learning · Computer Science 2024-07-19 Ling Yue , Jonathan Li , Sixue Xing , Md Zabirul Islam , Bolun Xia , Tianfan Fu , Jintai Chen

The Mamba architecture has been widely applied to various low-level vision tasks due to its exceptional adaptability and strong performance. Although the Mamba architecture has been adopted for spectral reconstruction, it still faces the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Yuze Zhang , Lingjie Li , Qiuzhen Lin , Zhong Ming , Fei Yu , Victor C. M. Leung

Scientific applications in fields such as high energy physics, computational fluid dynamics, and climate science generate vast amounts of data at high velocities. This exponential growth in data production is surpassing the advancements in…

Machine Learning · Computer Science 2024-09-10 Xiao Li , Jaemoon Lee , Anand Rangarajan , Sanjay Ranka

Recent advances in protein language models (PLMs) have demonstrated remarkable capabilities in understanding protein sequences. However, the extent to which different model architectures capture antibody-specific biological properties…

Machine Learning · Computer Science 2025-12-11 Mengren , Liu , Yixiang Zhang , Yiming , Zhang

Adapting models pre-trained on large-scale datasets to a variety of downstream tasks is a common strategy in deep learning. Consequently, parameter-efficient fine-tuning methods have emerged as a promising way to adapt pre-trained models to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 Ahmed Agiza , Marina Neseem , Sherief Reda

Low-Rank Adaptation (LoRA) has emerged as an efficient method for fine-tuning large language models (LLMs) and is widely adopted within the open-source community. However, the decentralized dissemination of LoRA adapters through platforms…

Cryptography and Security · Computer Science 2025-12-23 Linzhi Chen , Yang Sun , Hongru Wei , Yuqi Chen

Click-Through Rate (CTR) prediction is a pivotal task in product and content recommendation, where learning effective feature embeddings is of great significance. However, traditional methods typically learn fixed feature representations…

Information Retrieval · Computer Science 2023-09-06 Chen Zhu , Liang Du , Hong Chen , Shuang Zhao , Zixun Sun , Xin Wang , Wenwu Zhu

DFT-based machine-learning potentials (MLPs) are now routinely trained for condensed-phase systems, but surpassing DFT accuracy remains challenging due to the cost or unavailability of periodic reference calculations. Our previous work (PRL…

Chemical Physics · Physics 2025-02-25 Bence Balázs Mészáros , András Szabó , János Daru

Multi-head Latent Attention (MLA), the attention used in DeepSeek-V2/V3, jointly compresses keys and values into a low-rank latent and matches the H100 roofline almost perfectly. Its trained weights, however, expose only one decoding path -…

Machine Learning · Computer Science 2026-05-28 Fanxu Meng

We consider a model-agnostic solution to the problem of Multi-Domain Learning (MDL) for multi-modal applications. Many existing MDL techniques are model-dependent solutions which explicitly require nontrivial architectural changes to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-01 Anthony Sicilia , Xingchen Zhao , Davneet Minhas , Erin O'Connor , Howard Aizenstein , William Klunk , Dana Tudorascu , Seong Jae Hwang

We propose a novel multi-task learning architecture, which allows learning of task-specific feature-level attention. Our design, the Multi-Task Attention Network (MTAN), consists of a single shared network containing a global feature pool,…

Computer Vision and Pattern Recognition · Computer Science 2019-04-08 Shikun Liu , Edward Johns , Andrew J. Davison

We propose a novel distance-based regularization method for deep metric learning called Multi-level Distance Regularization (MDR). MDR explicitly disturbs a learning procedure by regularizing pairwise distances between embedding vectors…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Yonghyun Kim , Wonpyo Park

Modern software systems often have to cope with uncertain operation conditions, such as changing workloads or fluctuating interference in a wireless network. To ensure that these systems meet their goals these uncertainties have to be…

Software Engineering · Computer Science 2023-06-05 Federico Quin , Danny Weyns , Omid Gheibi

Algorithmic bias often arises as a result of differential subgroup validity, in which predictive relationships vary across groups. For example, in toxic language detection, comments targeting different demographic groups can vary markedly…

Machine Learning · Computer Science 2023-03-08 Soumyajit Gupta , Sooyong Lee , Maria De-Arteaga , Matthew Lease

Reinforcement learning (RL) often necessitates a meticulous Markov Decision Process (MDP) design tailored to each task. This work aims to address this challenge by proposing a systematic approach to behavior synthesis and control for…

Robotics · Computer Science 2024-10-18 Jean-Pierre Sleiman , Mayank Mittal , Marco Hutter

Scheduling flexible sources to promote the integration of renewable generation is one fundamental problem for operating active distribution networks (ADNs). However, existing works are usually based on power flow models, which require…

Optimization and Control · Mathematics 2022-08-09 Ge Chen , Hongcai Zhang , Yonghua Song

Benefiting from massive corpora and advanced hardware, large language models (LLMs) exhibit remarkable capabilities in language understanding and generation. However, their performance degrades in scenarios where multiple tasks are…

Computation and Language · Computer Science 2023-10-24 Xiao Wang , Tianze Chen , Qiming Ge , Han Xia , Rong Bao , Rui Zheng , Qi Zhang , Tao Gui , Xuanjing Huang

Deploying real-time spatial perception on edge devices requires efficient multi-task models that leverage complementary task information while minimizing computational overhead. This paper introduces Multi-Mono-Hydra (M2H), a novel…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 U. V. B. L Udugama , George Vosselman , Francesco Nex
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