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Related papers: Identifying and Extracting Rare Disease Phenotypes…

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Extracting phenotypes from clinical text has been shown to be useful for a variety of clinical use cases such as identifying patients with rare diseases. However, reasoning with numerical values remains challenging for phenotyping in…

Computation and Language · Computer Science 2022-04-22 Ashwani Tanwar , Jingqing Zhang , Julia Ive , Vibhor Gupta , Yike Guo

Instruction-tuned Large Language Models (LLMs) have exhibited impressive language understanding and the capacity to generate responses that follow specific prompts. However, due to the computational demands associated with training these…

Computation and Language · Computer Science 2024-03-26 Yida Mu , Ben P. Wu , William Thorne , Ambrose Robinson , Nikolaos Aletras , Carolina Scarton , Kalina Bontcheva , Xingyi Song

Recent work has demonstrated substantial gains on many NLP tasks and benchmarks by pre-training on a large corpus of text followed by fine-tuning on a specific task. While typically task-agnostic in architecture, this method still requires…

OpenNotes enables patients to access EHR notes, but medical jargon can hinder comprehension. To improve understanding, we evaluated closed- and open-source LLMs for extracting and prioritizing key medical terms using prompting, fine-tuning,…

Computation and Language · Computer Science 2026-05-08 Won Seok Jang , Sharmin Sultana , Zonghai Yao , Hieu Tran , Zhichao Yang , Sunjae Kwon , Hong Yu

Large Language Models (LLMs) have been gaining increasing attention and demonstrated promising performance across a variety of Software Engineering (SE) tasks, such as Automated Program Repair (APR), code summarization, and code completion.…

Software Engineering · Computer Science 2024-04-18 Quanjun Zhang , Tongke Zhang , Juan Zhai , Chunrong Fang , Bowen Yu , Weisong Sun , Zhenyu Chen

Language models, especially transformer-based ones, have achieved colossal success in NLP. To be precise, studies like BERT for NLU and works like GPT-3 for NLG are very important. If we consider DNA sequences as a text written with an…

Genomics · Quantitative Biology 2026-01-21 Musa Nuri Ihtiyar , Arzucan Ozgur

Recent studies have demonstrated promising performance of ChatGPT and GPT-4 on several medical domain tasks. However, none have assessed its performance using a large-scale real-world electronic health record database, nor have evaluated…

Computation and Language · Computer Science 2023-07-18 Jingqing Zhang , Kai Sun , Akshay Jagadeesh , Mahta Ghahfarokhi , Deepa Gupta , Ashok Gupta , Vibhor Gupta , Yike Guo

Named entity recognition (NER) stands as a fundamental and pivotal task within the realm of Natural Language Processing. Particularly within the domain of Biomedical Method NER, this task presents notable challenges, stemming from the…

Computation and Language · Computer Science 2024-07-01 Chen Tang , Bohao Yang , Kun Zhao , Bo Lv , Chenghao Xiao , Frank Guerin , Chenghua Lin

Large language models (LLMs) can be used as accessible and intelligent chatbots by constructing natural language queries and directly inputting the prompt into the large language model. However, different prompt' constructions often lead to…

Computation and Language · Computer Science 2023-12-14 Jinta Weng , Jiarui Zhang , Yue Hu , Daidong Fa , Xiaofeng Xuand , Heyan Huang

Automatic Speech Recognition (ASR) technology is fundamental in transcribing spoken language into text, with considerable applications in the clinical realm, including streamlining medical transcription and integrating with Electronic…

Computation and Language · Computer Science 2024-03-27 Nima Ebadi , Kellen Morgan , Adrian Tan , Billy Linares , Sheri Osborn , Emma Majors , Jeremy Davis , Anthony Rios

This study is dedicated to exploring the application of prompt learning methods to advance Named Entity Recognition (NER) within the medical domain. In recent years, the emergence of large-scale models has driven significant progress in NER…

Computation and Language · Computer Science 2025-06-04 Jinzhu Yang

Few-shot learning-the ability to train models with access to limited data-has become increasingly popular in the natural language processing (NLP) domain, as large language models such as GPT and T0 have been empirically shown to achieve…

Software Engineering · Computer Science 2023-06-16 Robert Kraig Helmeczi , Mucahit Cevik , Savas Yıldırım

Objective: Fluoropyrimidines are widely prescribed for colorectal and breast cancers, but are associated with toxicities such as hand-foot syndrome and cardiotoxicity. Since toxicity documentation is often embedded in clinical notes, we…

Computation and Language · Computer Science 2025-10-24 Xizhi Wu , Madeline S. Kreider , Philip E. Empey , Chenyu Li , Yanshan Wang

Background: Several studies show that large language models (LLMs) struggle with phenotype-driven gene prioritization for rare diseases. These studies typically use Human Phenotype Ontology (HPO) terms to prompt foundation models like GPT…

Computation and Language · Computer Science 2026-02-19 Zhanliang Wang , Da Wu , Quan Nguyen , Kai Wang

The emergence of generative Large Language Models (LLMs) emphasizes the need for accurate and efficient prompting approaches. LLMs are often applied in Few-Shot Learning (FSL) contexts, where tasks are executed with minimal training data.…

Computation and Language · Computer Science 2024-01-24 David Oniani , Jordan Hilsman , Hang Dong , Fengyi Gao , Shiven Verma , Yanshan Wang

As an effective approach to tune pre-trained language models (PLMs) for specific tasks, prompt-learning has recently attracted much attention from researchers. By using \textit{cloze}-style language prompts to stimulate the versatile…

Computation and Language · Computer Science 2021-08-25 Ning Ding , Yulin Chen , Xu Han , Guangwei Xu , Pengjun Xie , Hai-Tao Zheng , Zhiyuan Liu , Juanzi Li , Hong-Gee Kim

Despite the huge and continuous advances in computational linguistics, the lack of annotated data for Named Entity Recognition (NER) is still a challenging issue, especially in low-resource languages and when domain knowledge is required…

Computation and Language · Computer Science 2021-11-25 Valerio La Gatta , Vincenzo Moscato , Marco Postiglione , Giancarlo Sperlì

In recent years, single cell RNA sequencing has become a widely used technique to study cellular diversity and function. However, accurately annotating cell types from single cell data has been a challenging task, as it requires extensive…

Genomics · Quantitative Biology 2023-04-07 Zehua Zeng , Hongwu Du

Over the last few years, large language models (LLMs) have emerged as the most important breakthroughs in natural language processing (NLP) that fundamentally transform research and developments in the field. ChatGPT represents one of the…

Computation and Language · Computer Science 2023-04-13 Viet Dac Lai , Nghia Trung Ngo , Amir Pouran Ben Veyseh , Hieu Man , Franck Dernoncourt , Trung Bui , Thien Huu Nguyen

ChatGPT has revolutionized many research and industrial fields. ChatGPT has shown great potential in software engineering to boost various traditional tasks such as program repair, code understanding, and code generation. However, whether…

Software Engineering · Computer Science 2023-04-18 Jialun Cao , Meiziniu Li , Ming Wen , Shing-chi Cheung