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Highly-interconnected societies difficult to model the spread of infectious diseases such as COVID-19. Single-region SIR models fail to account for incoming forces of infection and expanding them to a large number of interacting regions…

Machine Learning · Computer Science 2023-11-06 Adrian Rojas-Campos , Lukas Stelz , Pascal Nieters

In the wake of the 2020 COVID-19 epidemic, much work has been performed on the development of mathematical models for the simulation of the epidemic, and of disease models generally. Most works follow the susceptible-infected-removed (SIR)…

Numerical Analysis · Mathematics 2022-05-18 Nicola Guglielmi , Elisa Iacomini , Alex Viguerie

Epidemiological models are best suitable to model an epidemic if the spread pattern is stationary. To deal with non-stationary patterns and multiple waves of an epidemic, we develop a hybrid model encompassing epidemic modeling, particle…

Machine Learning · Computer Science 2024-02-01 Naresh Kumar , Seba Susan

In this paper, we propose a new real-time differential virus transmission model, which can give more accurate and robust short-term predictions of COVID-19 transmitted infectious disease with benefits of near-term trend projection.…

Populations and Evolution · Quantitative Biology 2020-05-05 Sheldon X. D. Tan , Liang Chen

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

Game theory has been an effective tool in the control of disease spread and in suggesting optimal policies at both individual and area levels. In this paper, we propose a multi-region SEIR model based on stochastic differential game theory,…

Optimization and Control · Mathematics 2021-03-10 Yao Xuan , Robert Balkin , Jiequn Han , Ruimeng Hu , Hector D. Ceniceros

This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of…

Dynamical Systems · Mathematics 2025-11-18 Kristina Kehrer , Martin Weiser , Tim Conrad

We propose an epidemiological model using an adaptive dynamic three compartment (with four states) SIR(D) model. Our approach is similar to non-parametric curve fitting in spirit and automatically adapts to key external factors, such as…

Applications · Statistics 2020-09-14 Madhuchhanda Bhattacharjee , Arup Bose

The COVID-19 pandemic represents the most significant public health disaster since the 1918 influenza pandemic. During pandemics such as COVID-19, timely and reliable spatio-temporal forecasting of epidemic dynamics is crucial. Deep…

Machine Learning · Computer Science 2020-11-25 Lijing Wang , Aniruddha Adiga , Srinivasan Venkatramanan , Jiangzhuo Chen , Bryan Lewis , Madhav Marathe

Analysing and understanding the transmission and evolution of the COVID-19 pandemic is mandatory to be able to design the best social and medical policies, foresee their outcomes and deal with all the subsequent socio-economic effects. We…

Populations and Evolution · Quantitative Biology 2025-07-28 Radu D. Stochiţoiu , Marian Petrica , Traian Rebedea , Ionel Popescu , Marius Leordeanu

In this article, we consider a dynamic epidemiology model for the spread of the COVID-19 infection. Starting from the classical SEIR model, the model is modified so as to better describe characteristic features of the underlying pathogen…

Populations and Evolution · Quantitative Biology 2020-05-22 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

Genetic variations in the COVID-19 virus are one of the main causes of the COVID-19 pandemic outbreak in 2020 and 2021. In this article, we aim to introduce a new type of model, a system coupled with ordinary differential equations (ODEs),…

Analysis of PDEs · Mathematics 2022-03-29 Xiaoqian Gong , Benedetto Piccoli

Whenever countries are threatened by a pandemic, as is the case with the COVID-19 virus, governments should take the right actions to safeguard public health as well as to mitigate the negative effects on the economy. In this regard, there…

Machine Learning · Computer Science 2020-05-18 Luis Miralles-Pechuán , Fernando Jiménez , Hiram Ponce , Lourdes Martínez-Villaseñor

This paper is concerned with nonlinear modeling and analysis of the COVID-19 pandemic currently ravaging the planet. There are two objectives: to arrive at an appropriate model that captures the collected data faithfully, and to use that as…

Populations and Evolution · Quantitative Biology 2020-10-15 C. A. K. Kwuimy , Foad Nazari , Xun Jiao , Pejman Rohani , C. Nataraj

The current global health emergency triggered by the pandemic COVID-19 is one of the greatest challenges mankind face in this generation. Computational simulations have played an important role to predict the development of the current…

Populations and Evolution · Quantitative Biology 2020-06-11 Kok Yew Ng , Meei Mei Gui

SARS-CoV2, which causes coronavirus disease (COVID-19) is continuing to spread globally and has become a pandemic. People have lost their lives due to the virus and the lack of counter measures in place. Given the increasing caseload and…

This paper presents a detailed mathematical investigation into the dynamics of COVID-19 infections through extended Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological models. By…

Populations and Evolution · Quantitative Biology 2025-05-21 Caleb Traxler , Minh Ton , Nameer Ahmed , Sasha Prostota , Annie Cheng

The coronavirus disease 2019 (COVID-19) pandemic radically impacts our lives, while the transmission/infection and recovery dynamics of COVID-19 remain obscure. A time-dependent Susceptible, Exposed, Infectious, and Recovered (SEIR) model…

Populations and Evolution · Quantitative Biology 2020-04-01 Yong Zhang , Xiangnan Yu , HongGuang Sun , Geoffrey R. Tick , Wei Wei , Bin Jin

We propose an SEIR-type meta-population model to simulate and monitor the Covid-19 epidemic evolution. The basic model consists of seven compartments, namely susceptible (S), exposed (E), three infective classes, recovered (R), and deceased…

Populations and Evolution · Quantitative Biology 2020-11-18 Vinicius V. L. Albani , Roberto M. Velho , Jorge P. Zubelli

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

Methodology · Statistics 2022-06-17 Adam Spannaus , Theodore Papamarkou , Samantha Erwin , J. Blair Christian
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