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Magnetic particle imaging (MPI) is an imaging modality exploiting the nonlinear magnetization behavior of (super-)paramagnetic nanoparticles to obtain a space- and often also time-dependent concentration of a tracer consisting of these…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Sören Dittmer , Tobias Kluth , Mads Thorstein Roar Henriksen , Peter Maass

We contribute to the mathematical modeling and analysis of magnetic particle imaging which is a promising new in-vivo imaging modality. Concerning modeling, we develop a structured decomposition of the imaging process and extract its core…

Numerical Analysis · Mathematics 2016-05-27 Thomas März , Andreas Weinmann

Magnetic particle imaging (MPI) is a relatively new imaging modality. The nonlinear magnetization behavior of nanoparticles in an applied magnetic field is employed to reconstruct an image of the concentration of nanoparticles. Finding a…

Applied Physics · Physics 2018-07-04 Tobias Kluth

Magnetic Particle Imaging (MPI) is a promising tracer-based, functional medical imaging technique which measures the non-linear magnetization response of magnetic nanoparticles to a dynamic magnetic field. For image reconstruction, system…

Image and Video Processing · Electrical Eng. & Systems 2021-08-26 Christina Brandt , Christiane Schmidt

We propose a novel unsupervised deep-learning-based algorithm for dynamic magnetic resonance imaging (MRI) reconstruction. Dynamic MRI requires rapid data acquisition for the study of moving organs such as the heart. Existing reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Jaejun Yoo , Kyong Hwan Jin , Harshit Gupta , Jerome Yerly , Matthias Stuber , Michael Unser

In Magnetic Particle Imaging (MPI), it is typically assumed that the studied specimen is stationary during the data acquisition. In practical applications however, the searched-for 3D distribution of the magnetic nanoparticles might show a…

Optimization and Control · Mathematics 2024-01-26 Marius Nitzsche , Bernadette N Hahn

The image reconstruction problem of the tomographic imaging technique magnetic particle imaging (MPI) requires the solution of a linear inverse problem. One prerequisite for this task is that the imaging operator that describes the mapping…

Computational Physics · Physics 2019-07-12 Tobias Kluth , Patryk Szwargulski , Tobias Knopp

Magnetic Particle Imaging (MPI) is a promising tomographic technique for visualizing the spatio-temporal distribution of superparamagnetic nanoparticles, with applications ranging from cancer detection to real-time cardiovascular…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Vladyslav Gapyak , Thomas März , Andreas Weinmann

Magnetic particle imaging (MPI) is a medical imaging modality of recent origin, and it exploits the nonlinear magnetization phenomenon to recover the spatially dependent concentration of the nanoparticles. Currently, image reconstruction in…

Numerical Analysis · Mathematics 2019-04-23 Tobias Kluth , Bangti Jin

The paper surveys variational approaches for image reconstruction in dynamic inverse problems. Emphasis is on methods that rely on parametrised temporal models. These are here encoded as diffeomorphic deformations with time dependent…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Andreas Hauptmann , Ozan Öktem , Carola Schönlieb

Magnetic Particle Imaging (MPI) is a preclinical imaging technique capable of visualizing the spatio-temporal distribution of magnetic nanoparticles. The image reconstruction of this fast and dynamic process relies on efficiently solving an…

Numerical Analysis · Mathematics 2021-09-15 Florian Lieb , Tobias Knopp

Magnetic particle imaging (MPI) is an emerging medical imaging modality which offers a unique combination of high temporal and spatial resolution, sensitivity and biocompatibility. For system-matrix (SM) based image reconstruction in MPI, a…

Software Engineering · Computer Science 2024-01-12 Anselm von Gladiss , Amir Shayan Ahmadian , Jan Jürjens

This paper proposes a novel framework to reconstruct the dynamic magnetic resonance images (DMRI) with motion compensation (MC). Due to the inherent motion effects during DMRI acquisition, reconstruction of DMRI using motion…

Computer Vision and Pattern Recognition · Computer Science 2019-02-15 Ningning Zhao , Daniel O'Connor , Adrian Basarab , Dan Ruan , Peng Hu , Ke Sheng

Magnetic Particle Imaging (MPI) is a novel medical imaging modality. One of the established methods for MPI reconstruction is based on the System Matrix (SM). However, the calibration of the SM is often time-consuming and requires repeated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Xuqing Geng , Lei Su , Zhongwei Bian , Zewen Sun , Jiaxuan Wen , Jie Tian , Yang Du

Dynamic MRI reconstruction from undersampled measurements is a challenging inverse problem that requires preserving both spatial reconstruction quality and temporal consistency across the frames of the cine series. While recent…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Yongliang Sun , Siddhant Gautam , Chaoyan Huang , Nicole Seiberlich , Ismail Alkhouri , Saiprasad Ravishankar

Magnetic particle imaging (MPI) is an imaging method that can visualize magnetic nanoparticles in positive contrast, without radiation exposure. Recently, we proposed an image reconstruction method for projection-based MPI (pMPI), in which…

Medical Physics · Physics 2023-05-01 Kenya Murase

We derive a new 3D model for magnetic particle imaging (MPI) that is able to incorporate realistic magnetic fields in the reconstruction process. In real MPI scanners, the generated magnetic fields have distortions that lead to deformed…

Numerical Analysis · Mathematics 2020-12-30 Gaël Bringout , Wolfgang Erb , Jürgen Frikel

Magnetic resonance imaging (MRI) is highly susceptible to patient motion due to its relatively long acquisition times and the fact that data are acquired sequentially in k-space. Even small patient movements introduce phase inconsistencies…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Antonio Ortiz-Gonzalez , Erich Kobler , Lukas Schletter , Alexander Effland

Magnetic Particle Imaging (MPI) is a highly sensitive imaging method that enables the visualization of magnetic tracer materials with a temporal resolution of more than 46 volumes per second. In MPI the size of the field of view scales with…

Magnetic particle imaging (MPI) is a tracer-based imaging modality that detects superparamagnetic iron oxide nanoparticles in vivo, with applications in cancer cell tracking, lymph node mapping, and cell therapy monitoring. We introduce a…

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