Related papers: Accelerated, physics-inspired inference of skeleta…
Accurate understanding of muscle activation and muscle forces plays an essential role in neuro-rehabilitation and musculoskeletal disorder treatments. Computational musculoskeletal modeling has been widely used as a powerful non-invasive…
Skeletal muscles are living tissues that can undergo large deformations in short periods of time and that can be activated to produce force. In this paper we use the principles of continuum mechanics to propose a dynamic, fully non-linear,…
Computational biomechanical analysis plays a pivotal role in understanding and improving human movements and physical functions. Although physics-based modeling methods can interpret the dynamic interaction between the neural drive to…
In model-based medical image analysis, three features of interest are the shape of structures of interest, their relative pose, and image intensity profiles representative of some physical property. Often, these are modelled separately…
Objective: Soft-tissue sarcoma spreads preferentially along muscle fibers. We explore the utility of deriving muscle fiber orientations from diffusion tensor MRI (DT-MRI) for defining the boundary of the clinical target volume in muscle…
Magnetic resonance imaging (MRI) enables non-invasive, high-resolution analysis of muscle structures. However, automated segmentation remains limited by high computational costs, reliance on large training datasets, and reduced accuracy in…
This study presents an innovative computer vision framework designed to analyze human movements in industrial settings, aiming to enhance biomechanical analysis by integrating seamlessly with existing software. Through a combination of…
Computational models of complex physical systems often rely on simplifying assumptions which inevitably introduce model error, with consequent predictive errors. Given data on model observables, the estimation of parameterized model-error…
Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…
Purpose: From the myofibrils to the whole muscle scale, muscle micro-constituents exhibit passive and active mechanical properties, potentially coupled to electrical, chemical, and thermal properties. Experimental characterization of some…
This work presents a multi-resolution physics-informed recurrent neural network (MR PI-RNN), for simultaneous prediction of musculoskeletal (MSK) motion and parameter identification of the MSK systems. The MSK application was selected as…
Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…
Positron emission tomography (PET) reconstruction is a critical challenge in molecular imaging, often hampered by noise amplification, structural blurring, and detail loss due to sparse sampling and the ill-posed nature of inverse problems.…
The Gaussian Process (GP) assumption is often used in functional data analysis. We propose a method to assess departures from the GP assumption, both in terms of the shape of the distribution and its potential dependence on covariates,…
3D brain MRI studies often examine subtle morphometric differences between cohorts that are hard to detect visually. Given the high cost of MRI acquisition, these studies could greatly benefit from image syntheses, particularly…
In a large-scale medical examination, the UK Biobank study has successfully imaged more than 32,000 volunteer participants with magnetic resonance imaging (MRI). Each scan is linked to extensive metadata, providing a comprehensive medical…
The use of machine learning in Structural Health Monitoring is becoming more common, as many of the inherent tasks (such as regression and classification) in developing condition-based assessment fall naturally into its remit. This chapter…
Magnetic resonance imaging (MRI) is highly susceptible to patient motion due to its relatively long acquisition times and the fact that data are acquired sequentially in k-space. Even small patient movements introduce phase inconsistencies…
Magnetic Resonance Imaging (MRI) is a powerful medical imaging modality, but unfortunately suffers from long scan times which, aside from increasing operational costs, can lead to image artifacts due to patient motion. Motion during the…
Magnetic resonance imaging (MRI) is the gold standard imaging modality for numerous diagnostic tasks, yet its usefulness is tempered due to its high cost and infrastructural requirements. Low-cost very-low-field portable scanners offer new…