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Computational materials science and chemistry span vast knowledge domains and fractured software ecosystems. Although large language models (LLMs) have demonstrated research capabilities, scaling monolithic agents to manage the rigor and…

Supervised machine learning approaches have been increasingly used in accelerating electronic structure prediction as surrogates of first-principle computational methods, such as density functional theory (DFT). While numerous quantum…

Chemical Physics · Physics 2024-03-22 Haiyang Yu , Meng Liu , Youzhi Luo , Alex Strasser , Xiaofeng Qian , Xiaoning Qian , Shuiwang Ji

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine…

Quantitative Methods · Quantitative Biology 2015-06-19 Ali Faisal , Jaakko Peltonen , Elisabeth Georgii , Johan Rung , Samuel Kaski

Machine learning interatomic potentials (MLIPs) have become widely used tools in atomistic simulations. For much of the history of this field, the most commonly employed architectures were based on short-ranged atomic energy contributions,…

Chemical Physics · Physics 2026-03-17 William J. Baldwin , Ilyes Batatia , Martin Vondrák , Johannes T. Margraf , Gábor Csányi

Machine learning interatomic potentials (MLIPs) have become a workhorse of modern atomistic simulations, and recently published universal MLIPs, pre-trained on large datasets, have demonstrated remarkable accuracy and generalizability.…

Materials Science · Physics 2024-12-04 Juno Nam , Jiayu Peng , Rafael Gómez-Bombarelli

Cross-domain data integration drives interdisciplinary data reuse and knowledge transfer across domains. However, each discipline maintains its own metadata schemas and domain ontologies, employing distinct conceptual models and application…

The development of machine learning interatomic potentials faces a critical computational bottleneck with the generation and labeling of useful training datasets. We present a novel application of determinantal point processes (DPPs) to the…

Applications · Statistics 2026-03-24 Joanna Zou , Youssef Marzouk

Polymers-macromolecular systems composed of repeating chemical units-constitute the molecular foundation of living organisms, while their synthetic counterparts drive transformative advances across medicine, consumer products, and energy…

Machine-learning interatomic potentials (MLIPs) have greatly extended the reach of atomic-scale simulations, offering the accuracy of first-principles calculations at a fraction of the cost. Leveraging large quantum mechanical databases and…

Background: The secure management of sensitive clinical data, particularly human genomics data, has become a critical requirement in modern biomedical research. Although the necessary software and algorithms are readily available, their use…

Cryptography and Security · Computer Science 2024-01-17 Michael Huttner , Jakob Simeth , Renato Liguori , Fulvia Ferrazzi , Rainer Spang

Every research project necessitates data, often requiring sharing and collaborative review within a team. However, there is a dearth of good open-source data sharing and reviewing services. Existing file-sharing services generally mandate…

Databases · Computer Science 2024-06-27 Lexington Whalen , Homayoun Valafar

Information technology and data science development stimulate transformation in many fields of scientific knowledge. In recent years, a large number of specialized systems for information and knowledge management have been created in…

Materials Science · Physics 2025-10-09 Victor Dudarev , Lars Banko , Alfred Ludwig

Cloud-native databases have become the de-facto choice for mission-critical applications on the cloud due to the need for high availability, resource elasticity, and cost efficiency. Meanwhile, driven by the increasing connectivity between…

Data is a precious resource in today's society, and is generated at an unprecedented and constantly growing pace. The need to store, analyze, and make data promptly available to a multitude of users introduces formidable challenges in…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-06-08 Alessandro Margara , Gianpaolo Cugola , Nicolò Felicioni , Stefano Cilloni

Data management can be a complex challenge in fields such as bioinformatics and health sciences, which continuously generate extensive heterogeneous datasets. In the context of collaborative global health initiatives, secure storage and…

Software Engineering · Computer Science 2026-05-20 Danilo Silva , Monika Moir , Cheryl Baxter , Tulio de Oliveira , Joicymara Xavier , Marcel Dunaiski

Force matching is an established technique to generate effective potentials for molecular dynamics simulations from first-principles data. This method has been implemented in the open source code potfit. Here, we present a review of the…

The availability of large-scale datasets on which to train, benchmark and test algorithms has been central to the rapid development of machine learning as a discipline and its maturity as a research discipline. Despite considerable…

Quantum Physics · Physics 2021-08-17 Elija Perrier , Akram Youssry , Chris Ferrie

Machine learning interatomic potentials (MLIPs) have become powerful tools to extend molecular simulations beyond the limits of quantum methods, offering near-quantum accuracy at much lower computational cost. Yet, developing reliable MLIPs…

Materials Science · Physics 2025-12-30 Adam Lahouari , Jutta Rogal , Mark E. Tuckerman

Publicly available data from open sources (e.g., United States Census Bureau (Census), World Health Organization (WHO), Intergovernmental Panel on Climate Change (IPCC)) are vital resources for policy makers, students and researchers across…

The rapid growth in the number of experimental and predicted protein structures and more complicated protein structures challenge users in computational biology for utilizing the structural information and protein surface property…

Quantitative Methods · Quantitative Biology 2023-08-08 Junkang Wei , Jin Xiao , Siyuan Chen , Licheng Zong , Xin Gao , Yu Li
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