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Computed ultrasound tomography in echo mode generates maps of tissue speed of sound (SoS) from the shift of echoes when detected under varying steering angles. It solves a linearized inverse problem that requires regularization to…

Medical Physics · Physics 2026-04-23 Parisa Salemi Yolgunlu , Jules Blom , Naiara Korta Martiartu , Michael Jaeger

Speed-of-sound (SoS) is a biomechanical characteristic of tissue, and its imaging can provide a promising biomarker for diagnosis. Reconstructing SoS images from ultrasound acquisitions can be cast as a limited-angle computed-tomography…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Sonia Laguna , Lin Zhang , Can Deniz Bezek , Monika Farkas , Dieter Schweizer , Rahel A. Kubik-Huch , Orcun Goksel

Photoacoustic tomography (PAT) enables non-invasive cross-sectional imaging of biological tissues, but it fails to map the spatial variation of speed-of-sound (SOS) within tissues. While SOS is intimately linked to density and elastic…

Medical Physics · Physics 2024-08-27 Yang Wang , Danni Wang , Liting Zhong , Yi Zhou , Qing Wang , Wufan Chen , Li Qi

Volumetric, multimodal imaging with precise spatial and temporal co-registration can provide valuable and complementary information for diagnosis and monitoring. Considerable research has sought to combine 3D photoacoustic (PA) and…

We describe a technique to reveal speed-of-sound (SoS) variations within an echogenic sample. The technique uses the same receive data as standard pulse-echo imaging based on plane-wave compounding, and can be operated in parallel.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Nikunj Khetan , Timothy Weber , Jerome Mertz

One of the primary sources of suboptimal image quality in ultrasound imaging is phase aberration. It is caused by spatial changes in sound speed over a heterogeneous medium, which disturbs the transmitted waves and prevents coherent…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Mostafa Sharifzadeh , Sobhan Goudarzi , An Tang , Habib Benali , Hassan Rivaz

Speed-of-sound is a biomechanical property for quantitative tissue differentiation, with great potential as a new ultrasound-based image modality. A conventional ultrasound array transducer can be used together with an acoustic mirror, or…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Valery Vishnevskiy , Sergio J Sanabria , Orcun Goksel

Ultrasound imaging systems rely on accurate point spread function (PSF) estimation to support advanced image quality enhancement techniques such as deconvolution and speckle reduction. Phase aberration, caused by sound speed inhomogeneity…

Signal Processing · Electrical Eng. & Systems 2025-02-24 Wei-Hsiang Shen , Yu-An Lin , Meng-Lin Li

One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Anthony DiSpirito , Daiwei Li , Tri Vu , Maomao Chen , Dong Zhang , Jianwen Luo , Roarke Horstmeyer , Junjie Yao

Accurate speed-of-sound (SoS) estimation is crucial for ultrasound image formation, yet conventional systems often rely on an assumed value for imaging. We propose to leverage conventional image analysis techniques and metrics as a novel…

Image and Video Processing · Electrical Eng. & Systems 2026-04-08 Roman Denkin , Orcun Goksel

Quantitative ultrasound, e.g., speed-of-sound (SoS) in tissues, provides information about tissue properties that have diagnostic value. Recent studies showed the possibility of extracting SoS information from pulse-echo ultrasound raw data…

Image and Video Processing · Electrical Eng. & Systems 2022-07-07 Farnaz Khun Jush , Markus Biele , Peter M. Dueppenbecker , Andreas Maier

Photoacoustic (PA) imaging has been widely applied in both preclinical and clinical applications. With a significantly increasing number of data acquisition channels, fast and high-quality image reconstruction for real-time PA imaging is an…

Medical Physics · Physics 2024-08-20 Zijian Gao , Yuting Shen , Daohuai Jiang , Fengyu Liu , Feng Gao , Fei Gao

The quality of the reconstructed photoacoustic image largely depends on the amount of photoacoustic (PA) boundary data available, which in turn is proportional to the number of detectors employed. In case of limited data (owing to less…

Image and Video Processing · Electrical Eng. & Systems 2020-01-20 Navchetan Awasthi , Rohit Pardasani , Sandeep Kumar Kalva , Manojit Pramanik , Phaneendra K. Yalavarthy

Synthetic aperture sonar (SAS) measures a scene from multiple views in order to increase the resolution of reconstructed imagery. Image reconstruction methods for SAS coherently combine measurements to focus acoustic energy onto the scene.…

Image and Video Processing · Electrical Eng. & Systems 2023-06-19 Albert W. Reed , Juhyeon Kim , Thomas Blanford , Adithya Pediredla , Daniel C. Brown , Suren Jayasuriya

Applying standard algorithms to sparse data problems in photoacoustic tomography (PAT) yields low-quality images containing severe under-sampling artifacts. To some extent, these artifacts can be reduced by iterative image reconstruction…

Numerical Analysis · Mathematics 2024-12-20 Stephan Antholzer , Johannes Schwab , Robert Nuster , Markus Haltmeier

Deep-learning-based super-resolution photoacoustic angiography (PAA) is a powerful tool that restores blood vessel images from under-sampled images to facilitate disease diagnosis. Nonetheless, due to the scarcity of training samples, PAA…

Image and Video Processing · Electrical Eng. & Systems 2023-05-03 Yuanzheng Ma , Wangting Zhou , Rui Ma , Sihua Yang , Yansong Tang , Xun Guan

Deep learning has been used to improve photoacoustic (PA) image reconstruction. One major challenge is that errors cannot be quantified to validate predictions when ground truth is unknown. Validation is key to quantitative applications,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Ruibo Shang , Geoffrey P. Luke , Matthew O'Donnell

Synthetic aperture sonar (SAS) requires precise positional and environmental information to produce well-focused output during the image reconstruction step. However, errors in these measurements are commonly present resulting in defocused…

Image and Video Processing · Electrical Eng. & Systems 2021-08-02 Isaac Gerg , Vishal Monga

Photoacoustic imaging (PAI) is an emerging biomedical imaging modality capable of providing both high contrast and high resolution of optical and UltraSound (US) imaging. When a short duration laser pulse illuminates the tissue as a target…

Signal Processing · Electrical Eng. & Systems 2018-01-19 Moein Mozaffarzadeh , Ali Mahloojifar , Mahdi Orooji

This paper presents a numerical study on a fast marching method based back projection reconstruction algorithm for photoacoustic tomography in heterogeneous media. Transcranial imaging is used here as a case study. To correct for the phase…

Medical Physics · Physics 2015-01-21 Tianren Wang , Yun Jing