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A polarization-multiplexed, dual-beam setup is proposed to expand the field of view for a swept source optical coherence tomography angiography (OCTA) system. This method used a Wollaston prism to split sample path light into two…

Medical Physics · Physics 2017-10-30 Jianlong Yang , Rahul Chandwani , Rui Zhao , Zhuo Wang , Yali Jia , David Huang , Gangjun Liu

Optical Coherence Tomography (OCT) is an emerging technique in the field of biomedical imaging, with applications in ophthalmology, dermatology, coronary imaging etc. OCT images usually suffer from a granular pattern, called speckle noise,…

Computer Vision and Pattern Recognition · Computer Science 2016-05-25 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Optical coherence tomography (OCT) has seen widespread success as an in vivo clinical diagnostic 3D imaging modality, impacting areas including ophthalmology, cardiology, and gastroenterology. Despite its many advantages, such as high…

The choroid provides oxygen and nourishment to the outer retina thus is related to the pathology of various ocular diseases. Optical coherence tomography (OCT) is advantageous in visualizing and quantifying the choroid in vivo. (1) The…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Huihong Zhang , Jianlong Yang , Kang Zhou , Fei Li , Yan Hu , Yitian Zhao , Ce Zheng , Xiulan Zhang , Jiang Liu

Optical Coherence Tomography (OCT) is an imaging modality that has been widely adopted for visualizing corneal, retinal and limbal tissue structure with micron resolution. It can be used to diagnose pathological conditions of the eye, and…

Image and Video Processing · Electrical Eng. & Systems 2019-05-08 Jiahong Ouyang , Tejas Sudharshan Mathai , Kira Lathrop , John Galeotti

Optical coherence tomography (OCT) is a widely used imaging technique in the micrometer regime, which gained accelerating interest in medical imaging in the last twenty years. In up-to-date OCT literature [5,6] certain simplifying…

Medical Physics · Physics 2024-02-23 Leopold Veselka , Lisa Krainz , Leonidas Mindrinos , Wolfgang Drexler , Peter Elbau

Histopathological analysis is crucial in artery characterization for coronary artery disease (CAD). However, histology requires an invasive and time-consuming process. In this paper, we propose to generate virtual histology staining using…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Xueshen Li , Hongshan Liu , Xiaoyu Song , Brigitta C. Brott , Silvio H. Litovsky , Yu Gan

Optical Coherence Tomography (OCT) is the primary imaging modality for detecting pathological biomarkers associated to retinal diseases such as Age-Related Macular Degeneration. In practice, clinical diagnosis and treatment strategies are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Thomas Kurmann , Pablo Márquez-Neila , Siqing Yu , Marion Munk , Sebastian Wolf , Raphael Sznitman

OCTA is a crucial non-invasive imaging technique for diagnosing and monitoring retinal diseases like diabetic retinopathy, age-related macular degeneration, and glaucoma. Current 2D-based methods for retinal vessel (RV) segmentation offer…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Chuang Liu , Nan Guo

Reliable automated analysis of Optical Coherence Tomography (OCT) imaging is crucial for diagnosing retinal disorders but faces a critical barrier: the need for expensive, labor-intensive expert annotations. Supervised deep learning models…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Tania Haghighi , Sina Gholami , Hamed Tabkhi , Minhaj Nur Alam

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

Medical Physics · Physics 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

Optical Coherence Tomography (OCT) is an emerging medical imaging modality for luminal organ diagnosis. The non-constant rotation speed of optical components in the OCT catheter tip causes rotational distortion in OCT volumetric scanning.…

Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-30 Yijie Zhang , Tairan Liu , Manmohan Singh , Yilin Luo , Yair Rivenson , Kirill V. Larin , Aydogan Ozcan

Optical coherence tomography (OCT) is used for non-invasive diagnosis of diabetic macular edema assessing the retinal layers. In this paper, we propose a new fully convolutional deep architecture, termed ReLayNet, for end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2017-07-10 Abhijit Guha Roy , Sailesh Conjeti , Sri Phani Krishna Karri , Debdoot Sheet , Amin Katouzian , Christian Wachinger , Nassir Navab

Optical coherence tomography (OCT) as retina imaging technology is currently used by ophthalmologist as a non-invasive and non-contact method for diagnosis of agerelated degeneration (AMD) and diabetic macular edema (DME) diseases. Fluid…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Elyas Rashno , Abdolreza Rashno , Sadegh Fadaei

Layer segmentation is important to quantitative analysis of retinal optical coherence tomography (OCT). Recently, deep learning based methods have been developed to automate this task and yield remarkable performance. However, due to the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Hong Liu , Dong Wei , Donghuan Lu , Xiaoying Tang , Liansheng Wang , Yefeng Zheng

Background: Computed Tomography Angiography (CTA) is crucial for cerebrovascular disease diagnosis. Dynamic CTA is a type of imaging that captures temporal information about the We aim to develop and evaluate two segmentation techniques to…

Medical Physics · Physics 2025-02-17 Shrikanth Yadav , Jisoo Kim , Geoffrey Young , Lei Qin

Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and…

Medical Physics · Physics 2019-07-02 Cerine Lal , Hrebesh M Subhash , Sergey Alexandrov , Martin J Leahy

Optical coherence tomography (OCT) is a noninvasive imaging modality which can be used to obtain depth images of the retina. The changing layer thicknesses can thus be quantified by analyzing these OCT images, moreover these changes have…

Computer Vision and Pattern Recognition · Computer Science 2018-03-15 Yufan He , Aaron Carass , Bruno M. Jedynak , Sharon D. Solomon , Shiv Saidha , Peter A. Calabresi , Jerry L. Prince
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