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This study systematically benchmarks several non-fault-tolerant quantum computing algorithms across four distinct optimization problems: max-cut, number partitioning, knapsack, and quantum spin glass. Our benchmark includes noisy…

Quantum Physics · Physics 2024-10-31 Santaro Kikuura , Ryoya Igata , Yuta Shingu , Shohei Watabe

Quantum computing has shown great potential in various quantum chemical applications such as drug discovery, material design, and catalyst optimization. Although significant progress has been made in quantum simulation of simple molecules,…

Quantum Physics · Physics 2023-05-30 Changsu Cao , Jinzhao Sun , Xiao Yuan , Han-Shi Hu , Hung Q. Pham , Dingshun Lv

Discrete combinatorial optimization consists in finding the optimal configuration that minimizes a given discrete objective function. An interpretation of such a function as the energy of a classical system allows us to reduce the…

Quantum Physics · Physics 2015-06-22 Sergio Boixo , Gerardo Ortiz , Rolando Somma

Quantum computing offers a promising route for tackling hard optimization problems by encoding them as Ising models. However, sparse qubit connectivity requires the use of minor-embedding, mapping logical qubits onto chains of physical…

Quantum Physics · Physics 2025-03-12 Thang N. Dinh , Cao P. Cong

In the quantum optimization paradigm, variational quantum algorithms face challenges with hardware-specific and instance-dependent parameter tuning, which can lead to computational inefficiencies. The promising potential of parameter…

Realizing the potential of near-term quantum computers to solve industry-relevant constrained-optimization problems is a promising path to quantum advantage. In this work, we consider the extractive summarization constrained-optimization…

With the advent of novel quantum computing technologies, and the knowledge that such technology might be used to fundamentally change computing applications, a prime opportunity has presented itself to investigate the practical application…

Computational Engineering, Finance, and Science · Computer Science 2024-02-13 Kevin Wils , Boyang Chen

We propose a computational protocol for quantum simulations of Fermionic Hamiltonians on a quantum computer, enabling calculations which were previously not feasible with conventional encoding and ansatses of variational quantum…

Quantum Physics · Physics 2023-03-15 Benchen Huang , Nan Sheng , Marco Govoni , Giulia Galli

Quantum annealing is a promising algorithm for solving combinatorial optimization problems. It searches for the ground state of the Ising model, which corresponds to the optimal solution of a given combinatorial optimization problem. The…

Statistical Mechanics · Physics 2026-02-25 Tomohiro Hattori , Shu Tanaka

AlphaFold has achieved groundbreaking advancements in protein structure prediction, exerting profound influence across biology, medicine, and drug discovery. However, its reliance on multiple sequence alignment (MSA) is inherently…

Quantum Physics · Physics 2025-06-03 Rong Chen , Quan-Xin Mei , Wen-Ding Zhao , Lin Yao , Hao-Xiang Yang , Shun-Yao Zhang , Jiao Chen , Hong-Lin Li

Simulating charge and energy transfer in extended molecular networks requires an effective model to include the environment because it significantly affects the quantum dynamics. A prototypical effect known as Environment-Assisted Quantum…

Quantum Physics · Physics 2022-02-04 Federico Gallina , Matteo Bruschi , Barbara Fresch

Quantum computing promises to revolutionize several scientific and technological domains through fundamentally new ways of processing information. Among its most compelling applications is digital quantum simulation, where quantum computers…

Quantum Physics · Physics 2026-02-05 Laurin E. Fischer

Variational Quantum Algorithms (VQAs) provide a promising framework for tackling complex optimization problems on near-term quantum hardware. Here, we demonstrate that hybrid qubit--qumode quantum devices offer an efficient route to solving…

A circuit consisting of a network of coupled compound Josephson junction rf-SQUID flux qubits has been used to implement an adiabatic quantum optimization algorithm. It is shown that detailed knowledge of the magnitude of the persistent…

Mesoscale and Nanoscale Physics · Physics 2009-03-24 R. Harris , A. J. Berkley , J. Johansson , M. W. Johnson , T. Lanting , P. Bunyk , E. Tolkacheva , E. Ladizinsky , B. Bumble , A. Fung , A. Kaul , A. Kleinsasser , S. Han

Quantum neural networks hold significant promise for numerous applications, particularly as they can be executed on the current generation of quantum hardware. However, due to limited qubits or hardware noise, conducting large-scale…

Quantum technology is maturing to the point where quantum devices, such as quantum communication systems, quantum random number generators and quantum simulators, may be built with capabilities exceeding classical computers. A quantum…

The near-term utility of quantum computers is hindered by hardware constraints in the form of noise. One path to achieving noise resilience in hybrid quantum algorithms is to decrease the required circuit depth -- the number of applied…

Quantum Physics · Physics 2024-04-18 Erika Magnusson , Aaron Fitzpatrick , Stefan Knecht , Martin Rahm , Werner Dobrautz

The classical simulation of quantum algorithms is a crucial tool for circuit development, testing, and validation. Although acceleration using GPUs significantly reduces simulation time, most high-performance simulators rely on…

Optimization problems are ubiquitous in various industrial settings, and multi-knapsack optimization is one recurrent task faced daily by several industries. The advent of quantum computing has opened a new paradigm for computationally…

Large-scale quantum computers have the potential to hold computational capabilities beyond conventional computers for certain problems. However, the physical qubits within a quantum computer are prone to noise and decoherence, which must be…

Quantum Physics · Physics 2024-06-06 Luka Skoric , Dan E. Browne , Kenton M. Barnes , Neil I. Gillespie , Earl T. Campbell