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Generative pretraining (the "GPT" in ChatGPT) enables language models to learn from vast amounts of internet text without human supervision. This approach has driven breakthroughs across AI by allowing deep neural networks to learn from…

Neurons and Cognition · Quantitative Biology 2025-09-23 Thomas Serre , Ellie Pavlick

We present ProtoViT, a method for interpretable image classification combining deep learning and case-based reasoning. This method classifies an image by comparing it to a set of learned prototypes, providing explanations of the form ``this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Chiyu Ma , Jon Donnelly , Wenjun Liu , Soroush Vosoughi , Cynthia Rudin , Chaofan Chen

Extracting time-varying latent variables from computational cognitive models is a key step in model-based neural analysis, which aims to understand the neural correlates of cognitive processes. However, existing methods only allow…

Machine Learning · Computer Science 2025-09-01 Ti-Fen Pan , Jing-Jing Li , Bill Thompson , Anne Collins

While deep learning models have demonstrated remarkable success in numerous domains, their black-box nature remains a significant limitation, especially in critical fields such as medical image analysis and inference. Existing…

Machine Learning · Computer Science 2025-05-13 David Zucker

Machine learning is a rapidly evolving field with a wide range of applications, including biological signal analysis, where novel algorithms often improve the state-of-the-art. However, robustness to algorithmic variability - measured by…

Signal Processing · Electrical Eng. & Systems 2024-02-16 Tobias Ettling , Sari Saba-Sadiya , Gemma Roig

The deviation between chronological age and biological age is a well-recognized biomarker associated with cognitive decline and neurodegeneration. Age-related and pathology-driven changes to brain structure are captured by various…

Machine Learning · Computer Science 2022-11-01 Saurabh Sihag , Gonzalo Mateos , Corey McMillan , Alejandro Ribeiro

Brain age estimation from Magnetic Resonance Images (MRI) derives the difference between a subject's biological brain age and their chronological age. This is a potential biomarker for neurodegeneration, e.g. as part of Alzheimer's disease.…

Computer Vision and Pattern Recognition · Computer Science 2020-10-02 Kyriaki-Margarita Bintsi , Vasileios Baltatzis , Arinbjörn Kolbeinsson , Alexander Hammers , Daniel Rueckert

Recurrent Neural Networks (RNNs) have achieved remarkable performance on a range of tasks. A key step to further empowering RNN-based approaches is improving their explainability and interpretability. In this work we present MEME: a model…

Machine Learning · Computer Science 2021-04-15 Dmitry Kazhdan , Botty Dimanov , Mateja Jamnik , Pietro Liò

Explaining deep neural networks is challenging, due to their large size and non-linearity. In this paper, we introduce a concept-based explanation method, in order to explain the prediction for an individual class, as well as contrasting…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Rudolf Herdt , Daniel Otero Baguer

We jointly model longitudinal values of a psychometric test and diagnosis of dementia. The model is based on a continuous-time latent process representing cognitive ability. The link between the latent process and the observations is…

Statistics Theory · Mathematics 2007-06-13 Julien Ganiayre , Daniel Commenges , Luc Letenneur

The use of large pretrained neural networks to create contextualized word embeddings has drastically improved performance on several natural language processing (NLP) tasks. These computationally expensive models have begun to be applied to…

Computers and Society · Computer Science 2019-12-03 Benjamin Clavié , Kobi Gal

Reliable biomedical and clinical retrieval requires more than strong ranking performance: it requires a practical way to find systematic model failures and curate the training evidence needed to correct them. Late-interaction models such as…

Information Retrieval · Computer Science 2026-04-22 François Remy

Brain-Computer Interfaces (BCIs) based on P300 event-related potentials offer promising applications in health, education, and assistive technologies. However, challenges related to inter- and intra-subject variability and the…

Machine Learning · Computer Science 2026-05-12 Christian Oliva , Vinicio Changoluisa , Francisco B Rodríguez , Luis F Lago-Fernández

Since early machine learning models, metrics such as accuracy and precision have been the de facto way to evaluate and compare trained models. However, a single metric number doesn't fully capture the similarities and differences between…

Computer Vision and Pattern Recognition · Computer Science 2022-08-02 Ahmad Mustapha , Wael Khreich , Wes Masri

Recent concept-based interpretable models have succeeded in providing meaningful explanations by pre-defined concept sets. However, the dependency on the pre-defined concepts restricts the application because of the limited number of…

Artificial Intelligence · Computer Science 2025-02-19 Shin'ya Yamaguchi , Kosuke Nishida

We propose a novel approach that integrates machine learning into compartmental disease modeling to predict the progression of COVID-19. Our model is explainable by design as it explicitly shows how different compartments evolve and it uses…

In this paper, we propose DeepTree, a novel method for modeling trees based on learning developmental rules for branching structures instead of manually defining them. We call our deep neural model situated latent because its behavior is…

Machine Learning · Computer Science 2023-05-10 Xiaochen Zhou , Bosheng Li , Bedrich Benes , Songlin Fei , Sören Pirk

Interpretability is a key requirement for the use of machine learning models in high-stakes applications, including medical diagnosis. Explaining black-box models mostly relies on post-hoc methods that do not faithfully reflect the model's…

Artificial Intelligence · Computer Science 2024-06-25 Kerol Djoumessi , Bubacarr Bah , Laura Kühlewein , Philipp Berens , Lisa Koch

While originally designed for image generation, diffusion models have recently shown to provide excellent pretrained feature representations for semantic segmentation. Intrigued by this result, we set out to explore how well…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Rui Gong , Martin Danelljan , Han Sun , Julio Delgado Mangas , Luc Van Gool

How can we find interpretable, domain-appropriate models of natural phenomena given some complex, raw data such as images? Can we use such models to derive scientific insight from the data? In this paper, we propose some methods for…

Machine Learning · Computer Science 2024-02-06 Christopher J. Soelistyo , Alan R. Lowe