English
Related papers

Related papers: Prototype Learning for Explainable Brain Age Predi…

200 papers

Accurate brain age estimation from structural MRI is a valuable biomarker for studying aging and neurodegeneration. Traditional regression and CNN-based methods face limitations such as manual feature engineering, limited receptive fields,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Wasif Jalal , Md Nafiu Rahman , Atif Hasan Rahman , M. Sohel Rahman

Cell counting in biomedical imaging is pivotal for various clinical applications, yet the interpretability of deep learning models in this domain remains a significant challenge. We propose a novel prototype-based method for interpretable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Abdurahman Ali Mohammed , Wallapak Tavanapong , Catherine Fonder , Donald S. Sakaguchi

Brain aging, and more specifically the difference between the chronological and the biological age of a person, may be a promising biomarker for identifying neurodegenerative diseases. For this purpose accurate prediction is important but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Kyriaki-Margarita Bintsi , Vasileios Baltatzis , Alexander Hammers , Daniel Rueckert

Self-explaining deep models are designed to learn the latent concept-based explanations implicitly during training, which eliminates the requirement of any post-hoc explanation generation technique. In this work, we propose one such model…

Machine Learning · Computer Science 2021-12-02 Anirban Sarkar , Deepak Vijaykeerthy , Anindya Sarkar , Vineeth N Balasubramanian

Visual explanation (attention)-guided learning uses not only labels but also explanations to guide model reasoning process. While visual attention-guided learning has shown promising results, it requires a large number of explanation…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Yifei Zhang , Siyi Gu , Bo Pan , Guangji Bai , Meikang Qiu , Xiaofeng Yang , Liang Zhao

Timely and accurate diagnosis of neurodegenerative disorders, such as Alzheimer's disease, is central to disease management. Existing deep learning models require large-scale annotated datasets and often function as "black boxes".…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Duy-Cat Can , Quang-Huy Tang , Huong Ha , Binh T. Nguyen , Oliver Y. Chén

Interpretability and explainability of deep neural networks are challenging due to their scale, complexity, and the agreeable notions on which the explaining process rests. Previous work, in particular, has focused on representing internal…

Computation and Language · Computer Science 2020-11-09 Quan Tran , Nhan Dam , Tuan Lai , Franck Dernoncourt , Trung Le , Nham Le , Dinh Phung

The emergence of explainability methods has enabled a better comprehension of how deep neural networks operate through concepts that are easily understood and implemented by the end user. While most explainability methods have been designed…

Neurons and Cognition · Quantitative Biology 2022-03-17 Fernanda L. Ribeiro , Steffen Bollmann , Ross Cunnington , Alexander M. Puckett

The human brain undergoes rapid development during the third trimester of pregnancy. In this work, we model the neonatal development of the infant brain in this age range. As a basis, we use MR images of preterm- and term-birth neonates…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Florentin Bieder , Paul Friedrich , Hélène Corbaz , Alicia Durrer , Julia Wolleb , Philippe C. Cattin

The paper presents a novel deep learning approach, which extracts latent information from trained Deep Neural Networks (DNNs) and derives concise representations that are analyzed in an effective, unified way for prediction purposes. It is…

Machine Learning · Computer Science 2020-09-22 D. Kollias , N. Bouas , Y. Vlaxos , V. Brillakis , M. Seferis , I. Kollia , L. Sukissian , J. Wingate , S. Kollias

Classifying images with an interpretable decision-making process is a long-standing problem in computer vision. In recent years, Prototypical Part Networks has gained traction as an approach for self-explainable neural networks, due to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Zhijie Zhu , Lei Fan , Maurice Pagnucco , Yang Song

Despite outperforming the human in many tasks, deep neural network models are also criticized for the lack of transparency and interpretability in decision making. The opaqueness results in uncertainty and low confidence when deploying such…

Machine Learning · Computer Science 2017-09-14 Huijun Wu , Chen Wang , Jie Yin , Kai Lu , Liming Zhu

Brain aging is a regional phenomenon, a facet that remains relatively under-explored within the realm of brain age prediction research using machine learning methods. Voxel-level predictions can provide localized brain age estimates that…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Neha Gianchandani , Mahsa Dibaji , Johanna Ospel , Fernando Vega , Mariana Bento , M. Ethan MacDonald , Roberto Souza

Large language models can produce powerful contextual representations that lead to improvements across many NLP tasks. Since these models are typically guided by a sequence of learned self attention mechanisms and may comprise undesired…

Computation and Language · Computer Science 2019-10-14 Benjamin Hoover , Hendrik Strobelt , Sebastian Gehrmann

Large language models (LLMs) have demonstrated impressive performance on natural language tasks, but their decision-making processes remain largely opaque. Existing explanation methods either suffer from limited faithfulness to the model's…

Computation and Language · Computer Science 2025-06-03 Bowen Wei , Mehrdad Fazli , Ziwei Zhu

Prototypical Learning is based on the idea that there is a point (which we call prototype) around which the embeddings of a class are clustered. It has shown promising results in scenarios with little labeled data or to design explainable…

Machine Learning · Computer Science 2024-06-25 Antonio Almudévar , Théo Mariotte , Alfonso Ortega , Marie Tahon , Luis Vicente , Antonio Miguel , Eduardo Lleida

Though deep learning has shown successful performance in classifying the label and severity stage of certain diseases, most of them give few explanations on how to make predictions. Inspired by Koch's Postulates, the foundation in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-02 Yuhao Niu , Lin Gu , Yitian Zhao , Feng Lu

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Automatic and accurate segmentation of brain MR images throughout the human lifespan into tissue and structure is crucial for understanding brain development and diagnosing diseases. However, challenges arise from the intricate variations…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Lin Teng , Zihao Zhao , Jiawei Huang , Zehong Cao , Runqi Meng , Feng Shi , Dinggang Shen