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We report measurements of the brain activity of subjects engaged in behavioral exchanges with their environments. We observe brain states which are characterized by coordinated oscillation of populations of neurons that are changing rapidly…

Neurons and Cognition · Quantitative Biology 2007-05-23 Walter J. Freeman , Giuseppe Vitiello

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

Building upon our previous work on the Wilson-Cowan equations with distributed delays, we study the dynamic behavior in a system of two coupled Wilson-Cowan pairs. We focus in particular on understanding the mechanisms that govern the…

Dynamical Systems · Mathematics 2023-07-14 Eva Kaslik , Emanuel-Attila Kokovics , Anca Radulescu

We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show…

Adaptation and Self-Organizing Systems · Physics 2020-04-01 Jonathan D. Touboul , Charlotte Piette , Laurent Venance , G. Bard Ermentrout

The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…

Neurons and Cognition · Quantitative Biology 2021-02-03 J. Mendoza-Ruiz , C. E. Alonso-Malaver , M. Valderrama , O. A. Rosso , J. H. Martínez

Collective oscillations and their suppression by external stimulation are analyzed in a large-scale neural network consisting of two interacting populations of excitatory and inhibitory quadratic integrate-and-fire neurons. In the limit of…

Neurons and Cognition · Quantitative Biology 2021-07-14 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

The brain is a non-equilibrium system whose dynamics change in different brain states, such as wakefulness and deep sleep. Thermodynamics provides the tools for revealing these non-equilibrium dynamics. We used violations of the…

Biological Physics · Physics 2023-04-17 Gustavo Deco , Christopher Lynn , Yonatan Sanz Perl , Morten L. Kringelbach

We observe and study a self-organized phenomenon whereby the activity in a network of spiking neurons spontaneously terminates. We consider different types of populations, consisting of bistable model neurons connected electrically by gap…

Disordered Systems and Neural Networks · Physics 2018-11-22 Muhammet Uzuntarla , Joaquin J. Torres , Ali Çalım , Ernest Barreto

Knowing brain connectivity is of great importance both in basic research and for clinical applications. We are proposing a method to infer directed connectivity from zero-lag covariances of neuronal activity recorded at multiple sites. This…

Neurons and Cognition · Quantitative Biology 2018-04-10 Jonathan Schiefer , Alexander Niederbühl , Volker Pernice , Carolin Lennartz , Pierre LeVan , Jürgen Henning , Stefan Rotter

The cortex exhibits self-sustained highly-irregular activity even under resting conditions, whose origin and function need to be fully understood. It is believed that this can be described as an "asynchronous state" stemming from the…

Disordered Systems and Neural Networks · Physics 2019-10-24 Victor Buendía , Pablo Villegas , Serena di Santo , Alessandro Vezzani , Raffaella Burioni , Miguel A. Muñoz

Distributed networks of brain areas interact with one another in a time-varying fashion to enable complex cognitive and sensorimotor functions. Here we use novel network analysis algorithms to test the recruitment and integration of…

Neurons and Cognition · Quantitative Biology 2014-03-25 Danielle S. Bassett , Muzhi Yang , Nicholas F. Wymbs , Scott T. Grafton

The brain's functional connectivity fluctuates over time instead of remaining steady in a stationary mode even during the resting state. This fluctuation establishes the dynamical functional connectivity that transitions in a non-random…

Neurons and Cognition · Quantitative Biology 2022-03-28 Shikuang Deng , Jingwei Li , B. T. Thomas Yeo , Shi Gu

The response of thermodynamic systems perturbed out of an equilibrium steady-state is described by the reciprocal and the fluctuation-dissipation relations. The so-called fluctuation theorems extended the study of fluctuations far beyond…

Statistical Mechanics · Physics 2020-02-21 Matteo Polettini , Massimiliano Esposito

We address the problem of identifying functional interactions among stochastic neurons with variable-length memory from their spiking activity. The neuronal network is modeled by a stochastic system of interacting point processes with…

Applications · Statistics 2025-07-01 Ricardo F. Ferreira , Matheus E. Pacola , Vitor G. Schiavone , Rodrigo F. O. Pena

Many studies have shown that the excitation and inhibition received by cortical neurons remain roughly balanced across many conditions. A key question for understanding the dynamical regime of cortex is the nature of this balancing.…

Neurons and Cognition · Quantitative Biology 2019-08-29 Yashar Ahmadian , Kenneth D. Miller

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

Neurons and Cognition · Quantitative Biology 2014-03-05 Mathieu Galtier , Jonathan Touboul

Among the versatile forms of dynamical patterns of activity exhibited by the brain, oscillations are one of the most salient and extensively studied, yet are still far from being well understood. In this paper, we provide various structural…

Systems and Control · Electrical Eng. & Systems 2021-08-12 Erfan Nozari , Robert Planas , Jorge Cortes

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…

Neurons and Cognition · Quantitative Biology 2022-04-25 Rong Wang , Mianxin Liu , Xinhong Cheng , Ying Wu , Andrea Hildebrandt , Changsong Zhou

In dynamical models of cortical networks, the recurrent connectivity can amplify the input given to the network in two distinct ways. One is induced by the presence of near-critical eigenvalues in the connectivity matrix W, producing large…

Neurons and Cognition · Quantitative Biology 2012-07-31 Guillaume Hennequin , Tim P. Vogels , Wulfram Gerstner