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Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

Collective insights from a group of experts have always proven to outperform an individual's best diagnostic for clinical tasks. For the task of medical image segmentation, existing research on AI-based alternatives focuses more on…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Aimon Rahman , Jeya Maria Jose Valanarasu , Ilker Hacihaliloglu , Vishal M Patel

Diffusion models have shown impressive performance for generative modelling of images. In this paper, we present a novel semantic segmentation method based on diffusion models. By modifying the training and sampling scheme, we show that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe Valmaggia , Philippe C. Cattin

Medical image segmentation requires consensus ground truth segmentations to be derived from multiple expert annotations. A novel approach is proposed that obtains consensus segmentations from experts using graph cuts (GC) and semi…

Computer Vision and Pattern Recognition · Computer Science 2018-05-22 Dwarikanath Mahapatra

Medical image segmentation is crucial for accurate clinical diagnoses, yet it faces challenges such as low contrast between lesions and normal tissues, unclear boundaries, and high variability across patients. Deep learning has improved…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Houze Liu , Tong Zhou , Yanlin Xiang , Aoran Shen , Jiacheng Hu , Junliang Du

Variability in medical image segmentation, arising from annotator preferences, expertise, and their choice of tools, has been well documented. While the majority of multi-annotator segmentation approaches focus on modeling…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Kumar Abhishek , Jeremy Kawahara , Ghassan Hamarneh

The work discusses the use of machine learning algorithms for anomaly detection in medical image analysis and how the performance of these algorithms depends on the number of annotators and the quality of labels. To address the issue of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Hieu H. Pham , Khiem H. Le , Tuan V. Tran , Ha Q. Nguyen

Quantifying aleatoric uncertainty in medical image segmentation is critical since it is a reflection of the natural variability observed among expert annotators. A conventional approach is to model the segmentation distribution using the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Phi Van Nguyen , Ngoc Huynh Trinh , Duy Minh Lam Nguyen , Phu Loc Nguyen , Quoc Long Tran

Objective: Accurate probability estimates are essential for the safe deployment of medical image segmentation models in clinical decision-making. However, modern deep segmentation networks are often poorly calibrated, a problem exacerbated…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Meritxell Riera-Marín , Javier García López , Júlia Rodríguez-Comas , Miguel A. González Ballester , Adrian Galdran

Building an accurate computer-aided diagnosis system based on data-driven approaches requires a large amount of high-quality labeled data. In medical imaging analysis, multiple expert annotators often produce subjective estimates about…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Khiem H. Le , Tuan V. Tran , Hieu H. Pham , Hieu T. Nguyen , Tung T. Le , Ha Q. Nguyen

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Rushi Jiao , Yichi Zhang , Le Ding , Rong Cai , Jicong Zhang

Medical image segmentation annotation suffers from inter-rater variability (IRV) due to differences in annotators' expertise and the inherent blurriness of medical images. Standard approaches that simply average expert labels are flawed, as…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Chen Zhong , Yuxuan Yang , Xinyue Zhang , Ruohan Ma , Yong Guo , Gang Li , Jupeng Li

In computer-assisted surgery, automatically recognizing anatomical organs is crucial for understanding the surgical scene and providing intraoperative assistance. While machine learning models can identify such structures, their deployment…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Danush Kumar Venkatesh , Dominik Rivoir , Micha Pfeiffer , Fiona Kolbinger , Stefanie Speidel

In medical image segmentation tasks, diffusion models have shown significant potential. However, mainstream diffusion models suffer from drawbacks such as multiple sampling times and slow prediction results. Recently, consistency models, as…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Kejia Zhang , Lan Zhang , Haiwei Pan , Baolong Yu

Multi-rater annotations commonly occur when medical images are independently annotated by multiple experts (raters). In this paper, we tackle two challenges arisen in multi-rater annotations for medical image segmentation (called ambiguous…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Jinhong Wang , Yi Cheng , Jintai Chen , Hongxia Xu , Danny Chen , Jian Wu

The medical imaging literature has witnessed remarkable progress in high-performing segmentation models based on convolutional neural networks. Despite the new performance highs, the recent advanced segmentation models still require large,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 Nima Tajbakhsh , Laura Jeyaseelan , Qian Li , Jeffrey Chiang , Zhihao Wu , Xiaowei Ding

Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti

Annotation ambiguity due to inherent data uncertainties such as blurred boundaries in medical scans and different observer expertise and preferences has become a major obstacle for training deep-learning based medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yicheng Wu , Xiangde Luo , Zhe Xu , Xiaoqing Guo , Lie Ju , Zongyuan Ge , Wenjun Liao , Jianfei Cai

The robustness of image segmentation has been an important research topic in the past few years as segmentation models have reached production-level accuracy. However, like classification models, segmentation models can be vulnerable to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Othmane Laousy , Alexandre Araujo , Guillaume Chassagnon , Marie-Pierre Revel , Siddharth Garg , Farshad Khorrami , Maria Vakalopoulou

Segmentation is essential for medical image analysis tasks such as intervention planning, therapy guidance, diagnosis, treatment decisions. Deep learning is becoming increasingly prominent for segmentation, where the lack of annotations,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Firat Ozdemir , Zixuan Peng , Christine Tanner , Philipp Fuernstahl , Orcun Goksel
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