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Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

Interpretable machine learning has exploded as an area of interest over the last decade, sparked by the rise of increasingly large datasets and deep neural networks. Simultaneously, large language models (LLMs) have demonstrated remarkable…

Computation and Language · Computer Science 2024-02-06 Chandan Singh , Jeevana Priya Inala , Michel Galley , Rich Caruana , Jianfeng Gao

Current machine learning models are evaluated through behavioral snapshots, with benchmark accuracies, win rates and outcome-based metrics. Model explanations and evaluations, however, are fundamentally intertwined: understanding why a…

Computers and Society · Computer Science 2026-05-08 Isabelle Lee , Emmy Liu , Cathy Jiao , Brihi Joshi , Dani Yogatama , Fazl Barez , Michael Saxon

The thesis explores the role machine learning methods play in creating intuitive computational models of neural processing. Combined with interpretability techniques, machine learning could replace human modeler and shift the focus of human…

Neurons and Cognition · Quantitative Biology 2020-10-20 Ilya Kuzovkin

With Artificial Intelligence (AI) becoming ubiquitous in every application domain, the need for explanations is paramount to enhance transparency and trust among non-technical users. Despite the potential shown by Explainable AI (XAI) for…

Human-Computer Interaction · Computer Science 2024-02-05 Aditya Bhattacharya

Machine learning models need to provide contrastive explanations, since people often seek to understand why a puzzling prediction occurred instead of some expected outcome. Current contrastive explanations are rudimentary comparisons…

Human-Computer Interaction · Computer Science 2022-03-30 Wencan Zhang , Brian Y. Lim

Artificial intelligence-driven adaptive learning systems are reshaping education through data-driven adaptation of learning experiences. Yet many of these systems lack transparency, offering limited insight into how decisions are made. Most…

Artificial Intelligence · Computer Science 2025-08-04 Maryam Mosleh , Marie Devlin , Ellis Solaiman

The COVID-19 pandemic has forced many people to limit their social activities, which has resulted in a rise in mental illnesses, particularly depression. To diagnose these illnesses with accuracy and speed, and prevent severe outcomes such…

Machine Learning · Computer Science 2023-11-14 Hossein Simchi , Samira Tajik

The unprecedented performance of machine learning models in recent years, particularly Deep Learning and transformer models, has resulted in their application in various domains such as finance, healthcare, and education. However, the…

Human-Computer Interaction · Computer Science 2023-12-20 Milad Rogha

Artificial intelligence (AI) has rapidly developed through advancements in computational power and the growth of massive datasets. However, this progress has also heightened challenges in interpreting the "black-box" nature of AI models. To…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Shilin Sun , Wenbin An , Feng Tian , Fang Nan , Qidong Liu , Jun Liu , Nazaraf Shah , Ping Chen

Deep learning (DL) models have been popular due to their ability to learn directly from the raw data in an end-to-end paradigm, alleviating the concern of a separate error-prone feature extraction phase. Recent DL-based neuroimaging studies…

Machine Learning · Computer Science 2023-07-20 Md. Mahfuzur Rahman , Vince D. Calhoun , Sergey M. Plis

The field explainable artificial intelligence (XAI) has brought about an arsenal of methods to render Machine Learning (ML) predictions more interpretable. But how useful explanations provided by transparent ML methods are for humans…

Human-Computer Interaction · Computer Science 2021-07-06 Felix Biessmann , Dionysius Refiano

As cannabis use has increased in recent years, researchers have come to rely on sophisticated machine learning models to predict cannabis use behavior and its impact on health. However, many artificial intelligence (AI) models lack…

Human-Computer Interaction · Computer Science 2025-03-11 Tongze Zhang , Tammy Chung , Anind Dey , Sang Won Bae

The lack of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. While explainable artificial intelligence (XAI) methods have been proposed, little research has focused on the agreement between…

Machine Learning · Computer Science 2023-11-29 Aida Brankovic , Wenjie Huang , David Cook , Sankalp Khanna , Konstanty Bialkowski

Language Models (LMs) have significantly advanced natural language processing and enabled remarkable progress across diverse domains, yet their black-box nature raises critical concerns about the interpretability of their internal…

Computation and Language · Computer Science 2025-09-29 Avash Palikhe , Zichong Wang , Zhipeng Yin , Rui Guo , Qiang Duan , Jie Yang , Wenbin Zhang

Mechanistic interpretability aims to understand the computational mechanisms underlying neural networks' capabilities in order to accomplish concrete scientific and engineering goals. Progress in this field thus promises to provide greater…

Explainability is becoming an important requirement for organizations that make use of automated decision-making due to regulatory initiatives and a shift in public awareness. Various and significantly different algorithmic methods to…

Machine Learning · Computer Science 2021-07-12 Tom Vermeire , Thibault Laugel , Xavier Renard , David Martens , Marcin Detyniecki

Many ML models are opaque to humans, producing decisions too complex for humans to easily understand. In response, explainable artificial intelligence (XAI) tools that analyze the inner workings of a model have been created. Despite these…

Computers and Society · Computer Science 2021-06-17 Kiana Alikhademi , Brianna Richardson , Emma Drobina , Juan E. Gilbert

Artificial intelligence (AI) is revolutionizing many areas of our lives, leading a new era of technological advancement. Particularly, the transportation sector would benefit from the progress in AI and advance the development of…

Machine Learning · Computer Science 2022-10-19 Yanan Xin , Natasa Tagasovska , Fernando Perez-Cruz , Martin Raubal

The rise of AI conversational agents has broadened opportunities to enhance human capabilities across various domains. As these agents become more prevalent, it is crucial to investigate the impact of different affective abilities on their…

Human-Computer Interaction · Computer Science 2023-10-20 Javier Hernandez , Jina Suh , Judith Amores , Kael Rowan , Gonzalo Ramos , Mary Czerwinski
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